CD47 regulates collagen I-induced cyclooxygenase-2 expression and intestinal epithelial cell migration

PLoS ONE

Volumn 4, Issue 7, 2009, Pages

  Broom, Oliver Jay ^a   Zhang, Yuan ^a   Oldenborg, Per Arne ^b   Massoumi, Ramin ^a   Sjölander, Anita ^a  

^a LUND UNIVERSITY   (Sweden)

^b UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2 INTEGRIN; CD47 ANTIGEN; COLLAGEN TYPE 1; CYCLOOXYGENASE 2; F ACTIN; G PROTEIN COUPLED RECEPTOR; PERTUSSIS TOXIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ARTICLE; CELL ADHESION; CELL MIGRATION; CELL STRUCTURE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; BIOSYNTHESIS; CELL CULTURE; CELL MOTION; CYTOLOGY; ENZYME INDUCTION; IMMUNOLOGY; IMMUNOPRECIPITATION; INTESTINE MUCOSA; PHYSIOLOGY; WESTERN BLOTTING;

ANTIGENS, CD47; BLOTTING, WESTERN; CELL MOVEMENT; CELLS, CULTURED; COLLAGEN TYPE I; CYCLOOXYGENASE 2; ENZYME INDUCTION; HUMANS; IMMUNOPRECIPITATION; INTESTINAL MUCOSA;

EID: 68149138463     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006371     Document Type: Article

References (37)

1. Ristimaki A (2004) Cyclooxygenase 2: from inflammation to carcinogenesis. Novartis Found Symp 256: 215-221, 221-226, 259-269.
2. DuBois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, et al. (1998) Cyclooxygenase in biology and disease. FASEB J 12: 1063-1073.
3. Williams CS, Shattuck-Brandt RL, DuBois RN (1999) The role of COX-2 in intestinal cancer. Expert Opin Investig Drugs 8: 1-12.
4. Ekbom A, Helmick C, Zack M, Adami HO (1990) Ulcerative colitis and colorectal cancer. A population-based study. N Engl J Med 323: 1228-1233.
5. Itzkowitz SH, Yio X (2004) Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation. Am J Physiol 287: G7-17.
6. Singer II DW, Kawka S, Schloemann T, Tessner T, Riehl WF, Stenson (1998) Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease. Gastroenterology 115: 297-306.
7. Konturek PC, Kania J, Burnat G, Hahn EG, Konturek SJ (2005) Prostaglandins as mediators of COX-2 derived carcinogenesis in gastrointestinal tract. J Physiol Pharmacol 56 (5): 57-73.
8. Wendum D, Masliah J, Trugnan G, Flejou JF (2004) Cyclooxygenase-2 and its role in colorectal cancer development. Virchows Arch 445: 327-333.
9. Hynes RO, Lively JC, McCarty JH, Taverna D, Francis SE, Hodivala-Dilke K, Xiao Q (2002) The diverse roles of integrins and their ligands in angiogenesis. Cold Spring Harb Symp Quant Biol 67: 143-153.
10. Broom OJ, Massoumi R, Sjölander A (2006) Alpha2beta1 integrin signalling enhances cyclooxygenase-2 expression in intestinal epithelial cells. J Cell Physiol 209: 950-958.
11. Brabletz T, Spaderna S, Kolb J, Hlubek F, Faller G, et al. (2004) Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression. Cancer Res 64: 6973-6977.
12. Kokubo T, Uchida H, Choi E T (2007) Integrin alpha(v)beta(3) as a target in the prevention of neointimal hyperplasia. J Vasc Surg 45: A33-38.
13. Honoré S, Kovacic H, Pichard V, Briand C, Rognoni JB (2003) Alpha2beta1-integrin signaling by itself controls G1/S transition in a human adenocarcinoma cell line (Caco-2): implication of NADPH oxidase-dependent production of ROS. Exp Cell Res 285: 59-71.
14. Eisinger DA, Ammer H (2008) Delta-opioid receptors activate ERK/MAP kinase via integrin-stimulated receptor tyrosine kinases. Cell Signal 20: 2324-2331.
15. Hartmann TN, Grabovsky V, Pasvolsky R, Shulman Z, Buss EC, et al. (2008) A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells. J Leukocyte Biol 84: 1130-1140.
16. Juliano RL (2002) Signal transduction by cell adhesion receptors and the cytoskeleton: functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members. Annu Rev Pharmacol Toxicol 42: 283-323.
17. Lindberg FP, Gresham HD, Schwarz E, Brown EJ (1993) Molecular cloning of integrin-associated protein: an immunoglobulin family member with multiple membrane-spanning domains implicated in alpha v beta 3-dependent ligand binding. J Cell Biol 123: 485-496.
18. Campbell IG, Freemont PS, Foulkes W, Trowsdale J (1992) An ovarian tumor marker with homology to vaccinia virus contains an IgV-like region and multiple transmembrane domains. Cancer Res 52: 5416-5420.
19. Reinhold MI, Lindberg FP, Plas D, Reynolds S, Peters MG, Brown EJ (1995) In vivo expression of alternatively spliced forms of integrin-associated protein (CD47). J Cell Sci 108: 3419-3425.
20. Wang XQ, Lindberg FP, Frazier WA (1999I) protein stimulates alpha2beta1-dependent chemotaxis via Gi-mediated inhibition of adenylate cyclase and extracellular-regulated kinases. J Cell Biol 147: 389-400.
21. Wang XQ, Frazier WA (1998) The thrombospondin receptor CD47 (IAP) modulates and associates with alpha2 beta1 integrin in vascular smooth muscle cells. Mol Biol Cell 9: 865-874.
22. Green JM, Zhelesnyak A, Chung J, Lindberg FP, Sarfati M, et al. (1999) Role of cholesterol in formation and function of a signaling complex involving alphavbeta3, integrin-associated protein (CD47), and heterotrimeric G proteins. J Cell Biol 146: 673-682.
23. Chung J, Wang XQ, Lindberg FP, Frazier WA (1999) Thrombospondin-1 acts via IAP/CD47 to synergize with collagen in alpha2beta1-mediated platelet activation. Blood 94: 642-648.
24. 4 induces phosphatidylinositol 3-kinase and Rac-dependent migration of intestinal epithelial cells. J Biol Chem 280: 13538-13544.
25. 2 and upregulation of alpha2beta1-integrin. Exp Cell Res 289: 342-351.
26. Ishikawa-Sekigami T, Kaneko Y, Saito Y, Murata Y, Okazawa H, et al. (2006) Enhanced phagocytosis of CD47-deficient red blood cells by splenic macrophages requires SHPS-1. Biochem Biophys Res Commun 343: 1197-1200.
27. Henle G, Deinhardt F (1957) The establishment of strains of human cells in tissue culture. J Immunol 79: 54-59.
28. Gilchrist A, Vanhauwe JF, Li A, Thomas TO, Voyno-Yasenetskaya T, Hamm HEG (2001) alpha minigenes expressing C-terminal peptides serve as specific inhibitors of thrombin-mediated endothelial activation. J Biol Chem 276: 25672-25679.
29. Brown EJ, Frazier WA (2001) Integrin-associated protein (CD47) and its ligands. Trends Cell Biol 11: 130-135.
30. Larsen M, Artym VV, Green JA, Yamada KM (2006) The matrix reorganized: extracellular matrix remodeling and integrin signaling. Curr Opin Cell Biol 18: 463-471.
31. Friedl P, Weigelin B (2008) Interstitial leukocyte migration and immune function. Nature immunology 9: 960-969.
32. Frazier WA, Gao AG, Dimitry J, Chung J, Brown EJ, et al. (1999) The thrombospondin receptor integrin-associated protein (CD47) functionally couples to heterotrimeric Gi. J Biol Chem 274: 8554-8560.
33. Shinohara M, Ohyama N, Murata Y, Okazawa H, Ohnishi H, et al. (2006) CD47 regulation of epithelial cell spreading and migration, and its signal transduction. Cancer Sci 97: 889-895.
34. Friedl P (2004) Prespecification and plasticity: shifting mechanisms of cell migration. Curr Opin Cell Biol 16: 14-23.
35. Friedl P, Brocker EB (2004) Reconstructing leukocyte migration in 3D extracellular matrix by time-lapse videomicroscopy and computer-assisted tracking. Methods Mol Biol 239: 77-90.
36. Sahai E, Garcia-Medina R, Pouyssegur J, Vial E (2007) Smurf1 regulates tumor cell plasticity and motility through degradation of RhoA leading to localized inhibition of contractility. J Cell Biol 176: 35-42.
37. Carragher NO, Walker SM, Scott Carragher LA, Harris F, Sawyer TK, et al. (2006) Calpain 2 and Src dependence distinguishes mesenchymal and amoeboid modes of tumour cell invasion: a link to integrin function. Oncogene 25: 5726-5740.