P-glycoprotein modulation modifies ivermectin pharmacokinetics and its efficacy against resistant nematodes in lambs

Journal of Veterinary Pharmacology and Therapeutics

Volumn 32, Issue SUPPL. 1, 2009, Pages 74-

  Lifschitz, A ^a,b   Entrocasso, C ^c   Alvarez, L ^a,b   Lloberas, M ^c   Ballent, M ^a,b   Manazza, J ^c   Virkel, G ^a,b   Borda, B ^c   Lanusse, C ^a,b  

^a UNIVERSIDAD NACIONAL DEL CENTRO DE LA PROVINCIA DE BUENOS AIRES   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^c Estación Experimental INTA Balcarce   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

IVERMECTIN; LOPERAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTHELMINTIC ACTIVITY; BLOOD SAMPLING; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; FECES ANALYSIS; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LAMB; NEMATODE; NEMATODIASIS; NONHUMAN; PARASITOLOGY; PRIORITY JOURNAL; TRICHOSTRONGYLUS COLUBRIFORMIS;

NEMATODA; OVIS ARIES;

EID: 68149131046     PISSN: 01407783     EISSN: 13652885     Source Type: Journal    
DOI: 10.1111/j.1365-2885.2009.01090.x     Document Type: Conference Paper

References (6)

1. Lin, 2003, Adv Drug Deliv Rev, 55, 53-81
2. Laffont, et al., 2002, Drug Metab Dispos, 30, 626-630
3. Ballent, et al., 2006, Drug Metab Dispos, 34, 457-463
4. Lifschitz, et al., 2002, J Vet Pharmacol Ther, 25, 111-120
5. Lifschitz, et al., 2004, J Pharm Pharmacol, 56, 61-67
6. Prichard, Roulet, 2007, Parasitology, 134, 1123-1132