Severe allergic reaction with anaphylaxis to G-CSF (lenograstim) in a healthy donor

Bone Marrow Transplantation

Volumn 44, Issue 2, 2009, Pages 129-130

  Tulpule, S ^a   Shaw, B E ^a,b   Makoni, P ^a   Little, A M ^a   Madrigal, J A ^a   Goldman, J M ^a,c  

^a ROYAL FREE HOSPITAL   (United Kingdom)

^b ROYAL MARSDEN HOSPITAL   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ANTIHISTAMINIC AGENT; CHLORPHENIRAMINE; HYDROCORTISONE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ADULT; ANAPHYLAXIS; ARTICLE; BRADYCARDIA; BRONCHOSPASM; CASE REPORT; CHEST TIGHTNESS; CLINICAL FEATURE; DIZZINESS; DRUG RESPONSE; DYSPNEA; EYE DISEASE; EYE PUFFINESS; EYE REDNESS; HUMAN; HYPOTENSION; MALE; PRIORITY JOURNAL; TACHYCARDIA; TREATMENT RESPONSE;

ADULT; ANAPHYLAXIS; GRANULOCYTE COLONY-STIMULATING FACTOR; HEALTH; HUMANS; LIVING DONORS; MALE; RECOMBINANT PROTEINS; REFERENCE VALUES;

EID: 68149120540     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/bmt.2008.438     Document Type: Article

References (5)

1. Tigue CC, McKoy JM, Evens AM, Trifilio SM, Tallman MS, Bennett CL. Granulocyte-colony stimulating factor administration to healthy individuals and persons with with chronic neutropenia or cancer: An overview of safety considerations from the Research on Adverse Drug events and Reports project. 2007; 40: 185-192.
2. Cavallaro AM, Lilleby K, Majolino I, Storb R, Appelbaum FR, Rowley SD et al. Three to sixyear follow-up of normal donors who received recombinant human granulocyte colony stimulating factor. Bone Marrow Transplant 2000; 25: 85-89.
3. Khoury H, Adkins D, Brown R, Vij R, Westervelt P, Trinkaus K et al. Adverse side-effects associated with G-CSF in patients with chronic myeloid leukaemia undergoing allogeneic peripheral blood stem cell transplantation. Bone Marrow Transplant 2000; 25: 1197-1201.
4. Batel-Copel L, Mommeja-Marin H, Oudard S, Chavenet L, Pujade-Lauraine E, Coupier J et al. Anaphylactic reaction after first Filgrastim (granulocyte-colony stimulating factor) injection. Eur J Cancer 1995; 31A: 2428.
5. Jaiyesimi I, Giralt SS, Wood J. Subcutaneous granulocyte colony stimulating factor and acute anaphylaxis. N Engl Ji Med 1991; 325: 587.