Characterization of whole blood gene expression profiles as a sequel to globin mRNA reduction in patients with sickle cell disease

PLoS ONE

Volumn 4, Issue 8, 2009, Pages

  Raghavachari, Nalini ^a   Xu, Xiuli ^a   Munson, Peter J ^b   Gladwin, Mark T ^c  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLOBIN; ANTIOXIDANT; BETA GLOBIN; BIOLOGICAL MARKER; CHEMOKINE; COMPLEMENTARY RNA; CYTOKINE; GLOBIN; MESSENGER RNA; OXIDOREDUCTASE; PAIRED BOX TRANSCRIPTION FACTOR; RNA; STRUCTURAL PROTEIN;

ADULT; APOPTOSIS; ARTICLE; BIOTINYLATION; BLOOD ANALYSIS; BLOOD CLOTTING; CELL CYCLE REGULATION; CELLULAR STRESS RESPONSE; CLINICAL ARTICLE; COMPARATIVE GENE MAPPING; CONTROLLED STUDY; DEPLETION; ENZYME ACTIVITY; ERYTHROCYTE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REDUCTION; RNA STABILITY; RNA TRANSCRIPTION; SEQUENCE HOMOLOGY; SICKLE CELL ANEMIA; SIGNAL TRANSDUCTION; TOTAL QUALITY MANAGEMENT; TRANSCRIPTOMICS; UPREGULATION; BLOOD; DNA MICROARRAY; GENETICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANEMIA, SICKLE CELL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION PROFILING; GLOBINS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 68149116257     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006484     Document Type: Article

References (13)

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