Susceptibility for ischemic stroke in Korean population is associated with polymorphisms of the Fcγ receptor IIA

Blood Coagulation and Fibrinolysis

Volumn 20, Issue 5, 2009, Pages 353-357

  Kim, Yang Seok ^a   Yoo, Jin Ho ^b   Lee, Byung Cheol ^a  

^a Kyung Hee University   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

Fc receptors IIA; Ischemic stroke; Polymorphism

Indexed keywords

DNA; FC RECEPTOR IIA;

ADULT; ARTICLE; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA SEQUENCE; FEMALE; GENE INTERACTION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOME; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; BRAIN ISCHEMIA; COMORBIDITY; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; INFLAMMATION; KOREA; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, IGG; RISK FACTORS;

EID: 68149114495     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/MBC.0b013e32832a86fe     Document Type: Article

References (19)

1. Geng YJ, Wu Q, Muszynski M, HanssonGK, Libby P. Apoptosis ofvascular smooth muscle cells induced by in vitro stimulation with interferon-gamma, tumor necrosis factor-alpha, and interleukin-1 beta. Arterioscler Thromb Vasc Biol 1996; 16:19-27.
2. Ravetch JV. Fc receptors: rubor redux. Cell 1994; 78:553-560.
3. Sylvestre DL, Ravetch JV. Fc receptors initiate the Arthus reaction: redefining the inflammatory cascade. Science 1994; 265:1095-1098.
4. Pfeiffer JR, Howes PS, Waters MA, Hynes ML, Schnurr PP, Demidenko E, et al. Levels of expression of Fcgamma receptor IIA (CD32) are decreased on peripheral blood monocytes in patients with severe atherosclerosis. Atherosclerosis 2001; 155:211-218.
5. Rothe G, Gabriel H, Kovacs E, Klucken J, Stohr J, Kindermann W, et al. Peripheral blood mononuclear phagocyte subpopulations as cellular markers in hypercholesterolemia. Arterioscler Thromb Vasc Biol 1996; 16:1437-1447.
6. van der Meer IM, Witteman JC, Hofman A, Kluft C, de Maat MP. Genetic variation in Fcgamma receptor IIa protects against advanced peripheral atherosclerosis. The Rotterdam Study. Thromb Haemost 2004; 92:1273-1276.
7. Morgan AW, Robinson JI, Barrett JH, Martin J, Walker A, Babbage SJ, et al. Association of FCGR2A and FCGR2A-FCGR3A haplotypes with susceptibility to giant cell arteritis. Arthritis Res Ther 2006; 8:R109.
8. Harley JB, Alarcon-Riquelme ME, Criswell LA, Jacob CO, Kimberly RP, Moser KL, et al. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 2008; 40:204-210.
9. Wang SS, Cerhan JR, Hartge P, Davis S, Cozen W, Severson RK, et al. Common genetic variants in proinflammatory and other immunoregulatory genes and risk for non-Hodgkin lymphoma. Cancer Res 2006; 66:9771-9780.
10. Zhang W, Gordon M, Schultheis AM, Yang DY, Nagashima F, Azuma M, et al. FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab. J Clin Oncol 2007; 25:3712-3718.
11. SinhaS, Mishra SK, Sharma S, Patibandla PK, Mallick PK, Sharma SK,et al. Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population. Malar J 2008; 7:13.
12. Ozturk C, Aksu G, Berdeli A, Kutukculer N. Fc gamma RIIa, IIIa and IIIb polymorphisms in Turkish children susceptible to recurrent infectious diseases. Clin Exp Med 2006; 6:27-32.
13. Excoffier L, Slatkin M. Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol 1995; 12:921-927.
14. Salmon JE, Pricop L. Human receptors for immunoglobulin G: key elements in the pathogenesis of rheumatic disease. Arthritis Rheum 2001; 44:739-750.
15. Takai T. Roles of Fc receptors in autoimmunity. Nat Rev Immunol 2002; 2:580-592.
16. Komine-Kobayashi M, Chou N, Mochizuki H, Nakao A, Mizuno Y, Urabe T. Dual role of Fcgamma receptor in transient focal cerebral ischemia in mice. Stroke 2004; 35:958-963.
17. Ratcliffe NR, Kennedy SM, Morganelli PM. Immunocytochemical detection of Fcgamma receptors in human atherosclerotic lesions. Immunol Lett 2001; 77:169-174.
18. van de Winkel JG, Anderson CL. Biology of human immunoglobulin G Fc receptors. J Leukoc Biol 1991; 49:511-524.
19. Huang Y, Fleming AJ, Wu S, Virella G, Lopes-Virella MF. Fc-gamma receptor cross-linking by immune complexes induces matrix metalloproteinase-1 in U937 cells via mitogen-activated protein kinase. Arterioscler Thromb Vasc Biol 2000; 20:2533-2538.