Expression of transgenic PPP1CC2 in the testis of Ppp1cc-null mice rescues spermatid viability and spermiation but does not restore normal sperm tail ultrastructure, sperm motility, or fertility

Biology of Reproduction

Volumn 81, Issue 2, 2009, Pages 343-352

  Soler, David C ^a,c   Kadunganattil, Suraj ^a   Ramdas, Shandilya ^a   Myers, Kimberly ^a   Roca, Joaquim ^c   Slaughter, Theresa ^b   Pilder, Stephen H ^b   Vijayaraghavan, Srinivasan ^a  

^a KENT STATE UNIVERSITY   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

Author keywords

Sperm; Spermatid; Spermatogenesis; Testis

Indexed keywords

ISOENZYME; PHOSPHOPROTEIN PHOSPHATASE 1;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ULTRASTRUCTURE; CELL VIABILITY; CONTROLLED STUDY; FEMALE; GENE; GENE DELETION; GENE EXPRESSION REGULATION; HISTOLOGY; MALE; MALE FERTILITY; MEIOSIS; MOUSE; NONHUMAN; PPP1CC GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPERMATID; SPERMATOGENESIS; SPERMATOZOON MOTILITY; SPERMATOZOON TAIL; TRANSGENE; TRANSMISSION ELECTRON MICROSCOPY;

MUS;

ANIMALS; APOPTOSIS; CELL SURVIVAL; EMBRYO IMPLANTATION; EPIDIDYMIS; FEMALE; FERTILITY; GENE EXPRESSION; MALE; MICE; MICE, TRANSGENIC; ORGAN SPECIFICITY; PROMOTER REGIONS, GENETIC; PROTEIN ISOFORMS; PROTEIN PHOSPHATASE 1; RATS; RNA, MESSENGER; SPERM HEAD; SPERM MOTILITY; SPERM TAIL; SPERMATIDS; SPERMATOGENESIS; SPERMATOZOA; TESTIS; TRANSGENES;

EID: 68049143420     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.109.076398     Document Type: Article

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