Stability and liquid-liquid phase separation in mixed saturated lipid bilayers

Biophysical Journal

Volumn 96, Issue 10, 2009, Pages 3977-3986

  Longo, Gabriel S ^a,b   Schick, M ^c   Szleifer, I ^d  

^a SISSA   (Italy)

^b ABDUS SALAM INTERNATIONAL CENTRE FOR THEORETICAL PHYSICS   (Italy)

^c UNIVERSITY OF WASHINGTON   (United States)

^d Northwestern University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL MEMBRANE; HYDROPHOBICITY; LIPID BILAYER; METHODOLOGY; PARTITION COEFFICIENT; PHASE SEPARATION; PROTEIN STABILITY; CHEMICAL STRUCTURE; CHEMISTRY; ISOLATION AND PURIFICATION; SURFACE TENSION; TEMPERATURE;

PHOSPHATIDYLCHOLINE;

HYDROPHOBICITY; LIPID BILAYERS; MODELS, MOLECULAR; PHOSPHATIDYLCHOLINES; SURFACE TENSION; TEMPERATURE;

EID: 68049133060     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2009.02.043     Document Type: Article

References (49)

1. Mukherjee, S., and F. R. Maxfield. 2004. Membrane domains. Annu. Rev. Cell Dev. Biol. 20:839-866.
2. Shimshick, E. J., and H. M. McConnell. 1973. Lateral phase separation in phospholipid membranes. Biochemistry. 12:2351-2360.
3. Lentz, B. R., D. A. Barrow, and M. Hoechli. 1980. Cholesterol- phosphatidylcholine interactions in multilamellar vesicles. Biochemistry. 19:1943-1954.
4. Vist, M., and J. Davis. 1990. Phase equilibria of cholesterol/ dipalmitoylphosphatidylcholine mixtures: deuterium nuclear magnetic resonance and differential scanning calorimetry. Biochemistry. 29:451-464.
5. McMullen, T., and R. McElhaney. 1995. New aspects of the interaction of cholesterol with dipalmitoylphosphatidylcholine bilayers as revealed by high-sensitivity differential scanning calorimetry. Biochim. Biophys. Acta. 1234:90-98.
6. Loura, L., A. Fedorov, and M. Prieto. 2001. Fluid-fluid membrane microheterogeneity: a fluorescence resonance energy transfer study. Biophys. J. 80:776-788.
7. Dietrich, C., L. A. Bagatolli, Z. N. Volovyk, N. L. Thompson, M. Levi, et al. 2001. Lipid rafts reconstituted in model membranes. Biophys. J. 80:1417-1428.
8. Veatch, S. L., and S. L. Keller. 2002. Organization in lipid membranes containing cholesterol. Phys. Rev. Lett. 89:268101.
9. Veatch, S. L., and S. L. Keller. 2005. Seeing spots: complex phase behavior in simple membranes. Biochim. Biophys. Acta. 1746:172-185.
10. Edidin, M. 2003. The state of lipid rafts: from model membranes to cells. Annu. Rev. Biophys. Biomol. Struct. 32:257-283.
11. Munro, S. 2003. Lipid rafts: elusive of illusive? Cell. 115:377-388.
12. Simons, K., and W. Vaz. 2004. Model systems, lipid rafts, and cell membranes. Annu. Rev. Biophys. Biomol. Struct. 33:269-295.
13. McMullen, T., R. N. Lewis, and R. McElhaney. 2004. Cholesterolphospholipid interactions, the liquid-ordered phase and lipid rafts in model and biological membranes. Curr. Op. Coll. Int. Sci. 8:459-468.
14. Wu, S. H. W., and H. M. McConnell. 1975. Phase separations in phospholipid membranes. Biochemistry. 14:847-859.
15. Mabrey, S., and J. M. Sturtevant. 1976. Investigation of phase transitions of lipid mixtures by high sensitivity differential scanning calorimetry. Proc. Natl. Acad. Sci. USA. 73:3862-3866.
16. Knoll, W., K. Ibel, and E. Sackmann. 1981. Small-angle neutron scattering study of lipid phase diagrams by the contrast variation method. Biochemistry. 20:6379-6383.
17. Leidy, C., T. Kaasgaard, J. H. Crowe, O. G. Mouritsen, and K. Jorgensen. 2002. Ripples and the formation of anisotropic lipid domains: imaging two-component double bilayers by atomic force microscopy. Biophys. J. 83:2625-2633.
18. Kraft, M. L., P. K. Weber, M. L. Longo, I. D. Hutcheon, and S. G. Boxer. 2006. Phase separation of lipid membranes analyzed with high-resolution secondary ion mass spectrometry. Science. 313:1948-1951.
19. Lin, W. C., C. D. Blanchette, T. V. Ratto, and M. L. Longo. 2006. Lipid asymmetry in DLPC/DSPC-supported lipid bilayers: a combined AFM and fluorescence microscopy study. Biophys. J. 90:228-237.
20. Melchior, D. L. 1986. Lipid domains in fluid membranes: a quick-freeze differential scanning calorimetry study. Science. 234:1577-1580.
21. Lentz, B. R., Y. Barenholz, and T. E. Thompson. 1976. Fluorescence depolarization studies of phase transitions and fluidity in phospholipid bilayers. 2. Two-component phosphatidylcholine liposomes. Biochemistry. 15:4529-4537.
22. Bagatolli, L. A., and E. Gratton. 2000. Two photon fluorescence microscopy of coexisting lipid domains in giant unilamellar vesicles of binary phospholipid mixtures. Biophys. J. 78:290-305.
23. Knoll, W., G. Schmidt, and E. Sackmann. 1983. Critical demixing in fluid bilayers of phospholipid mixtures. A neutron diffraction study. J. Chem. Phys. 79:3439-3442.
24. Jorgensen, K., M. M. Sperotto, O. G. Mouritsen, J. H. Ipsen, and M. J. Zuckermann. 1993. Phase equilibria and local structure in binary lipid bilayers. Biochim. Biophys. Acta. 1152:135-145.
25. Risbo, J., M. M. Sperotto, and O. G. Mouritsen. 1995. Theory of phase equilibria and critical mixing points in binary lipid layers. J. Chem. Phys. 103:3643-3656.
26. Mouritsen, O. G., and M. Bloom. 1984. Mattress model of lipid-protein interactions in membranes. Biophys. J. 46:141-153.
27. Lehtonen, J. Y. A., J. M. Holopainen, and K. J. Kinnunen. 1996. Evidence for the formation of microdomains in liquid crystalline large unilamellar vesicles caused by hydrophobic mismatch of the constituent phospholipids. Biophys. J. 70:1753-1760.
28. Hashimoto, T., K. Yamasaki, and H. Hasegawa. 1993. Ordered structure in blends of block copolymers. 1. Miscibility criterion for lamellar block copolymers. Macromolecules. 26:2895-2904.
29. Matsen, M. 1995. Immiscibility of large and small symmetric diblock copolymers. J. Chem. Phys. 103:3268-3271.
30. Ben-Shaul, A., I. Szleifer, and W. Gelbart. 1985. Chain organization and thermodynamics in micelles and bilayers. I. Theory. J. Chem. Phys. 83:3597-3611.
31. Szleifer, I., A. Ben-Shaul, and W. Gelbart. 1985. Chain organization and thermodynamics in micelles and bilayers. II. Model calculations. J. Chem. Phys. 83:3612-3620.
32. Fattal, D. R., and A. Ben-Shaul. 1994. Mean-field calculations of chain packing and conformational statistics in lipid bilayers: comparison with experiments and molecular dynamics studies. Biophys. J. 67:983-995.
33. Elliot, R., K. Katsov, M. Schick, and I. Szleifer. 2005. Phase separation of saturated and mono-unsaturated lipids as determined from a microscopic model. J. Chem. Phys. 122:044904.
34. Seelig, J., and W. Niederberger. 1974. Two pictures of a lipid bilayer. A comparison between deuterium label and spin-label experiments. Biochemistry. 13:1585-1588.
35. 13C nuclear Overhauser effect study. J. Phys. Chem. 88:1655-1662.
36. Jönsson, B., O. Edholm, and O. Teleman. 1986. Molecular dynamics simulations of a sodium octanoate micelle in aqueous solution. J. Chem. Phys. 85:2259-2271.
37. Woods, M. C., J. M. Haile, and J. P. O'Connell. 1986. Internal structure of a model micelle via computer simulation. 2. Spherically confined aggregates with mobile heads groups. J. Phys. Chem. 90:1875-1885.
38. Szleifer, I., A. Ben-Shaul, and W. Gelbart. 1987. Statistical thermodynamics of molecular organization in mixed micelles and bilayers. J. Chem. Phys. 86:7094-7109.
39. Nagle, J. F., and S. Tristam-Nagle. 2000. Structure of lipid bilayers. Biochim. Biophys. Acta. 1469:159-195.
40. Flory, P. J. 1969. Statistical Mechanics of Chain Molecules. Wiley-Interscience, New York.
41. Israelachvili, J. 1991. Intermolecular and Surface Forces, 2nd Ed. Academic Press, New York.
42. Longo, G. S., D. H. Thompson, and I. Szleifer. 2007. Stability and phase separation in mixed monopolar lipid/bolalipid layers. Biophys. J. 93:2609-2621.
43. deGennes, P.-G. 1980. Conformation of polymers attached to an interface. Macromolecules. 13:1069-1075.
44. Honerkamp-Smith, A. R., P. Cicuta, M. D. Collins, S. Veatch, M. den Nijs, et al. 2008. Line tensions, correlation lengths, and critical exponents in lipid membranes near critical points. Biophys. J. 95:236-246.
45. Veatch, S., P. Cicuta, P. Sengupta, A. Honerkamp-Smith, D. Holowka, et al. 2008. Critical fluctuations in plasma membrane vesicles. ACS Chem. Biol. 3:287-293.
46. Dewa, T., Y. Miyake, F. Kézdy, and S. Regen. 2000. Types of lipid clustering in phospholipid membranes as classified by nearest-neighbor recognition analysis. Langmuir. 16:3735-3739.
47. Hancock, J. 2006. Lipid rafts: contentious only from simplistic standpoints. Nat. Rev. Mol. Cell Biol. 7:456-462.
48. Schick, M. 1990. Liquids at Interfaces. Elsevier Science, Amsterdam, The Netherlands.
49. Lifshitz, E. M., and L. P. Pitaevskii. 1980. Statistical Physics., 3rd Ed. Pergamon Press, Oxford, UK.