Detection of Hepatitis B Virus (HBV) DNA at femtomolar concentrations using a silica nanoparticle-enhanced microcantilever sensor

Biosensors and Bioelectronics

Volumn 25, Issue 1, 2009, Pages 130-135

  Cha, Byung Hak ^a,d   Lee, Sang Myung ^a,b   Park, Jae Chan ^c   Hwang, Kyo Seon ^a   Kim, Sang Kyung ^a   Lee, Yoon Sik ^b   Ju, Byeong Kwon ^d   Kim, Tae Song ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Seoul National University   (South Korea)

^c BioCore Institute of Biotechnology   (South Korea)

^d Korea University   (South Korea)

Author keywords

Dynamic microcantilever; HBV DNA; Sandwich assay; Sensitivity enhancement; Silica nanoparticles

Indexed keywords

DETECTION PROBES; DNA ASSAYS; DNA DETECTION; DNA HYBRIDIZATION; EFFICIENT DETECTION; FEMTOMOLAR CONCENTRATION; HBV DNA; HEPATITIS B VIRUS; MASS LOADINGS; MICRO CANTILEVER SENSORS; MICRO-CANTILEVERS; MICROCANTILEVER BIOSENSORS; NANOPARTICLE CONCENTRATIONS; PCR PRODUCTS; RESONANT FREQUENCIES; RESONANT FREQUENCY SHIFT; SANDWICH ASSAY; SENSITIVITY ENHANCEMENT; SIGNAL AMPLIFICATIONS; SIGNAL ENHANCEMENT; SILICA NANOPARTICLES; SPRING CONSTANTS;

AMPLIFICATION; ATOMIC FORCE MICROSCOPY; BIOSENSORS; COMPOSITE MICROMECHANICS; COMPUTER VIRUSES; DNA; FREQUENCY SHIFT KEYING; GENES; NATURAL FREQUENCIES; NUCLEIC ACIDS; PROBES; SIGNAL DETECTION; SIGNAL PROCESSING; SILICA; TARGETS;

NANOPARTICLES;

NANOPARTICLE; NUCLEOTIDE; SILICON DIOXIDE; VIRUS DNA;

ARTICLE; BIOSENSOR; CONJUGATION; DNA DETERMINATION; DNA HYBRIDIZATION; DNA PROBE; HEPATITIS B VIRUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; POLYMERASE CHAIN REACTION;

BIOSENSING TECHNIQUES; DNA, BACTERIAL; EQUIPMENT DESIGN; HEPATITIS B VIRUS; NANOPARTICLES; SENSITIVITY AND SPECIFICITY; SILICON DIOXIDE; SURFACE PROPERTIES;

HEPATITIS B VIRUS;

EID: 68049121836     PISSN: 09565663     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bios.2009.06.015     Document Type: Article

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