메뉴 건너뛰기




Volumn 41, Issue 7, 2009, Pages 478-486

Transcriptional activation of insulin-like growth factor binding protein 6 by 17β-estradiol in SaOS-2 cells

Author keywords

Estrogen; Insulin like growth factor binding protein 6; Osteoblasts; Receptors, estrogen; Transcription, genetic

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; ESTRADIOL; ESTROGEN RECEPTOR; MESSENGER RNA; SOMATOMEDIN BINDING PROTEIN 6;

EID: 68049115753     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2009.41.7.053     Document Type: Article
Times cited : (11)

References (48)
  • 2
    • 0028089998 scopus 로고
    • Recombinant human insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced differentiation of L6A1 myoblasts
    • DOI 10.1210/en.135.5.2168
    • Bach LA, Hsieh S, Brown AL, Rechler MM. Recombinant human insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced differentiation of L6A1 myoblasts. Endocrinology 1994;135:2168-2176 (Pubitemid 24363916)
    • (1994) Endocrinology , vol.135 , Issue.5 , pp. 2168-2176
    • Bach, L.A.1    Hsieh, S.2    Brown, A.L.3    Rechler, M.M.4
  • 4
    • 2042503711 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-6 transgenic mice: Postnatal growth, brain development, and reproduction abnormalities
    • DOI 10.1210/en.2003-1196
    • Bienvenu G, Seurin D, Grellier P, Froment P, Baudrimont M, Monget P, Le Bouc Y, Babajko S. Insulin-like growth factor binding protein-6 transgenic mice: postnatal growth, brain development, and reproduction abnormalities. Endocrinology 2004;145:2412-2420 (Pubitemid 38535070)
    • (2004) Endocrinology , vol.145 , Issue.5 , pp. 2412-2420
    • Bienvenu, G.1    Seurin, D.2    Grellier, P.3    Froment, P.4    Baudrimont, M.5    Monget, P.6    Le Bouc, Y.7    Babajko, S.8
  • 5
    • 0031765505 scopus 로고    scopus 로고
    • Estrogen receptor-α is developmentally regulated during osteoblast differentiation and contributes to selective responsiveness of gene expression
    • Bodine PV, Henderson RA, Green J, Aronow M, Owen T, Stein GS, Lian JB, Komm BS.Estrogen receptor-alpha is developmentally regulated during osteoblast differentiation and contributes to selective responsiveness of gene expression. Endocrinology 1998;139:2048-2057 (Pubitemid 28513868)
    • (1998) Endocrinology , vol.139 , Issue.4 , pp. 2048-2057
    • Bodine, P.V.N.1    Henderson, R.A.2    Green, J.3    Aronow, M.4    Owen, T.5    Stein, G.S.6    Lian, J.B.7    Komm, B.S.8
  • 6
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • May 7
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976 May 7;72:248-254
    • (1976) Anal Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 7
    • 0347717953 scopus 로고    scopus 로고
    • Resistance to different antiestrogens is caused by different multi-factorial changes and is associated with reduced expression of IGF receptor Iα
    • DOI 10.1677/erc.0.0100579
    • Brockdorff BL, Heiberg I, Lykkesfeldt AE. Resistance to different antiestrogens is caused by different multi-factorial changes and is associated with reduced expression of IGF receptor Ialpha. Endocr Relat Cancer 2003;10:579-590 (Pubitemid 38094892)
    • (2003) Endocrine-Related Cancer , vol.10 , Issue.4 , pp. 579-590
    • Brockdorff, B.L.1    Heiberg, I.2    Lykkesfeldt, A.E.3
  • 8
    • 0023801293 scopus 로고
    • Regional sex differences in cell nuclear estrogen-binding capacity in the rat hypothalamus and preoptic area
    • Brown TJ, Hochberg RB, Zielinski JE, MacLusky NJ. Regional sex differences in cell nuclear estrogen-binding capacity in the rat hypothalamus and preoptic area. Endocrinology 1988;123:1761-1770
    • (1988) Endocrinology , vol.123 , pp. 1761-1770
    • Brown, T.J.1    Hochberg, R.B.2    Zielinski, J.E.3    MacLusky, N.J.4
  • 9
    • 33746218695 scopus 로고    scopus 로고
    • Differentiation and growth inhibition mediated via the RXR:PPARγ heterodimer in colon cancer
    • DOI 10.1016/j.canlet.2005.09.010, PII S0304383505008591
    • Cesario RM, Stone J, Yen WC, Bissonnette RP, Lamph WW. Differentiation and growth inhibition mediated via the RXR:PPARgamma heterodimer in colon cancer. Cancer Lett 2006;240:225-233 (Pubitemid 44093823)
    • (2006) Cancer Letters , vol.240 , Issue.2 , pp. 225-233
    • Cesario, R.M.1    Stone, J.2    Yen, W.-C.3    Bissonnette, R.P.4    Lamph, W.W.5
  • 10
    • 0034121694 scopus 로고    scopus 로고
    • Assessment of estrogenicity by using the delayed implanting rat model and examples
    • Cummings AM, Laws SC.Assessment of estrogenicity by using the delayed implanting rat model and examples. Reprod Toxicol 2000;14:111-117
    • (2000) Reprod Toxicol , vol.14 , pp. 111-117
    • Cummings, A.M.1    Laws, S.C.2
  • 11
    • 0035911739 scopus 로고    scopus 로고
    • Structure and characterization of the human insulin-like growth factor binding protein (IGFBP)-6 promoter: Identification of a functional retinoid response element
    • DOI 10.1016/S0167-4781(01)00192-0, PII S0167478101001920
    • Dailly YP, Zhou Y, Linkhart TA, Baylink DJ, Strong DD. Structure and characterization of the human insulin-like growth factor binding protein (IGFBP)-6 promoter: identification of a functional retinoid response element. Biochim Biophys Acta 2001;1518:145-151 (Pubitemid 32232287)
    • (2001) Biochimica et Biophysica Acta - Gene Structure and Expression , vol.1518 , Issue.1-2 , pp. 145-151
    • Dailly, Y.P.1    Zhou, Y.2    Linkhart, T.A.3    Baylink, D.J.4    Strong, D.D.5
  • 12
    • 3042640661 scopus 로고    scopus 로고
    • Effect of an insulin-like growth factor binding protein fusion protein on thymidine incorporation in neuroblastoma and rhabdomyosarcoma cell lines
    • DOI 10.1210/en.2003-1667
    • Dake BL, Boes M, Bach LA, Bar RS. Effect of an insulin-like growth factor binding protein fusion protein on thymidine incorporation in neuroblastoma and rhabdomyosarcoma cell lines. Endocrinology 2004;145:3369-3374 (Pubitemid 38830009)
    • (2004) Endocrinology , vol.145 , Issue.7 , pp. 3369-3374
    • Dake, B.L.1    Boes, M.2    Bach, L.A.3    Bar, R.S.4
  • 14
    • 0023913120 scopus 로고
    • The steroid and thyroid hormone receptor superfamily
    • Evans RM. The steroid and thyroid hormone receptor superfamily. Science 1988;240:889-895
    • (1988) Science , vol.240 , pp. 889-895
    • Evans, R.M.1
  • 15
    • 34547946223 scopus 로고    scopus 로고
    • Promotion of cancer cell migration: An insulin-like growth factor (IGF)-independent action of IGF-binding protein-6
    • DOI 10.1074/jbc.M703066200
    • Fu P, Thompson JA, Bach LA. Promotion of cancer cell migration: an insulin-like growth factor (IGF)-independent action of IGF-binding protein-6. J Biol Chem 2007;282:22298-22306 (Pubitemid 47267353)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.31 , pp. 22298-22306
    • Fu, P.1    Thompson, J.A.2    Bach, L.A.3
  • 16
    • 0141706853 scopus 로고    scopus 로고
    • Urokinase Type Plasminogen Activator Receptor Is Involved in Insulin-Like Growth Factor-Induced Migration of Rhabdomyosarcoma Cells in Vitro
    • DOI 10.1002/jcp.10352
    • Gallicchio MA, Kaun C, Wojta J, Binder B, Bach LA. Urokinase type plasminogen activator receptor is involved in insulin-like growth factor-induced migration of rhabdomyosarcoma cells in vitro. J Cell Physiol 2003;197:131-138 (Pubitemid 37486235)
    • (2003) Journal of Cellular Physiology , vol.197 , Issue.1 , pp. 131-138
    • Gallicchio, M.A.1    Kaun, C.2    Wojta, J.3    Binder, B.4    Bach, L.A.5
  • 18
    • 0023797380 scopus 로고
    • Nuclear receptors enhance our understanding of transcription regulation
    • DOI 10.1016/0168-9525(88)90108-4
    • Green S, Chambon P.Nuclear receptors enhance our understanding of transcription regulation. Trends Genet 1988;4:309-314 (Pubitemid 18270497)
    • (1988) Trends in Genetics , vol.4 , Issue.11 , pp. 309-314
    • Green, S.1    Chambon, P.2
  • 19
    • 0032522834 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor-binding protein 6 complementary DNA alters neuroblastoma cell growth
    • Grellier P, De Galle B, Babajko S. Expression of insulin-like growth factor-binding protein 6 complementary DNA alters neuroblastoma cell growth. Cancer Res 1998;58:1670-1676 (Pubitemid 28215091)
    • (1998) Cancer Research , vol.58 , Issue.8 , pp. 1670-1676
    • Grellier, P.1    De Galle, B.2    Babajko, S.3
  • 20
    • 0348142223 scopus 로고    scopus 로고
    • Antiestrogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the gene expression of insulin-like growth factors family in osteoblast cells
    • Guo L, Zhao YY, Dong LY, Ding Q, Sun KL, Ji SJ, Wang LZ. Antiestrogenic effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the gene expression of insulin-like growth factors family in osteoblast cells.Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2003;20:490-494
    • (2003) Zhonghua Yi Xue Yi Chuan Xue Za Zhi , vol.20 , pp. 490-494
    • Guo, L.1    Zhao, Y.Y.2    Dong, L.Y.3    Ding, Q.4    Sun, K.L.5    Ji, S.J.6    Wang, L.Z.7
  • 23
    • 2542557724 scopus 로고    scopus 로고
    • Breast cancer: When proteomics challenges biological complexity
    • Hondermarck H. Breast cancer: when proteomics challenges biological complexity. Mol Cell Proteomics 2003;2:281-291
    • (2003) Mol Cell Proteomics , vol.2 , pp. 281-291
    • Hondermarck, H.1
  • 24
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: Biological actions
    • Jones JI, Clemmons DR. Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 1995;16:3-34
    • (1995) Endocr Rev , vol.16 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 25
    • 45049086100 scopus 로고    scopus 로고
    • Estrogen and the selective estrogen receptor modulator (SERM) protection against cell death in estrogen receptor alpha and beta expressing U2OS cells
    • Kallio A, Guo T, Lamminen E, Seppänen J, Kangas L, Vään̈nen HK, Ḧrk̈nen P. Estrogen and the selective estrogen receptor modulator (SERM) protection against cell death in estrogen receptor alpha and beta expressing U2OS cells. Mol Cell Endocrinol 2008;289:38-48
    • (2008) Mol Cell Endocrinol , vol.289 , pp. 38-48
    • Kallio, A.1    Guo, T.2    Lamminen, E.3    Seppänen, J.4    Kangas, L.5    Vään̈nen, H.K.6    Ḧrk̈nen, P.7
  • 26
    • 0036132226 scopus 로고    scopus 로고
    • Inhibition of Caco-2 cell proliferation by all-trans retinoic acid: Role of insulin-like growth factor binding protein-6.J
    • Kim EJ, Kang YH, Schaffer BS, Bach LA, MacDonald RG, Park JH. Inhibition of Caco-2 cell proliferation by all-trans retinoic acid: role of insulin-like growth factor binding protein-6.J Cell Physiol 2002;190:92-100
    • (2002) Cell Physiol , vol.190 , pp. 92-100
    • Kim, E.J.1    Kang, Y.H.2    Schaffer, B.S.3    Bach, L.A.4    MacDonald, R.G.5    Park, J.H.6
  • 28
    • 0030822421 scopus 로고    scopus 로고
    • Dimerizing the estrogen receptor DNA binding domain enhances binding to estrogen response elements
    • DOI 10.1074/jbc.272.44.27949
    • Kuntz MA, Shapiro DJ. Dimerizing the estrogen receptor DNA binding domain enhances binding to estrogen response elements. J Biol Chem 1997;272:27949-27956 (Pubitemid 27473600)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.44 , pp. 27949-27956
    • Kuntz, M.A.1    Shapiro, D.J.2
  • 29
    • 8444220819 scopus 로고    scopus 로고
    • Interactions between estrogen and mechanical strain effects on U2OS human osteosarcoma cells are not influenced by estrogen receptor type
    • DOI 10.1016/j.bone.2004.07.005, PII S875632820400300X
    • Lima F, Vico L, Lafage-Proust MH, van der Saag P, Alexandre C, Thomas T. Interactions between estrogen and mechanical strain effects on U2OS human osteosarcoma cells are not influenced by estrogen receptor type. Bone 2004;35:1127-1135 (Pubitemid 39487359)
    • (2004) Bone , vol.35 , Issue.5 , pp. 1127-1135
    • Lima, F.1    Vico, L.2    Lafage-Proust, M.-H.3    Van Der Saag, P.4    Alexandre, C.5    Thomas, T.6
  • 30
    • 0037418329 scopus 로고    scopus 로고
    • Estrogen is a critical determinant that specifies the duration of the window of uterine receptivity for implantation
    • Ma WG, Song H, Das SK, Paria BC, Dey SK.Estrogen is a critical determinant that specifies the duration of the window of uterine receptivity for implantation.Proc Natl Acad Sci U S A 2003;100:2963-2968
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2963-2968
    • Ma, W.G.1    Song, H.2    Das, S.K.3    Paria, B.C.4    Dey, S.K.5
  • 31
    • 0028804592 scopus 로고
    • Insulin-like growth factor-binding protein-3 production by MCF-7 breast cancer cells: Stimulation by retinoic acid and cyclic adenosine monophosphate and differential effects of estradiol
    • Martin JL, Coverley JA, Pattison ST, Baxter RC. Insulin-like growth factor-binding protein-3 production by MCF-7 breast cancer cells: stimulation by retinoic acid and cyclic adenosine monophosphate and differential effects of estradiol. Endocrinology 1995;136:1219-1226
    • (1995) Endocrinology , vol.136 , pp. 1219-1226
    • Martin, J.L.1    Coverley, J.A.2    Pattison, S.T.3    Baxter, R.C.4
  • 32
    • 0035047831 scopus 로고    scopus 로고
    • Insulin-like growth factor binding proteins in femoral and vertebral bone marrow stromal cells: Expression and regulation by thyroid hormone and dexamethasone
    • Department of Orthopedics and Physical Rehabilitation
    • Milne M, Quail JM, Rosen CJ, Baran DT.Insulin-like growth factor binding proteins in femoral and vertebral bone marrow stromal cells: expression and regulation by thyroid hormone and dexamethasone.Department of Orthopedics and Physical Rehabilitation. J Cell Biochem 2001;81:229-240
    • (2001) J Cell Biochem , vol.81 , pp. 229-240
    • Milne, M.1    Quail, J.M.2    Rosen, C.J.3    Baran, D.T.4
  • 33
    • 0029934522 scopus 로고    scopus 로고
    • Estrogen receptor affinity and location of consensus and imperfect estrogen response elements influence transcription activation of simplified promoters
    • DOI 10.1210/me.10.6.694
    • Nardulli AM, Romine LE, Carpo C, Greene GL, Rainish B. Estrogen receptor affinity and location of consensus and imperfect estrogen response elements influence transcription activation of simplified promoters. Mol Endocrinol 1996;10:694-704 (Pubitemid 26176277)
    • (1996) Molecular Endocrinology , vol.10 , Issue.6 , pp. 694-704
    • Nardulli, A.M.1    Romine, L.E.2    Carpo, C.3    Greene, G.L.4    Rainish, B.5
  • 34
    • 1942521206 scopus 로고    scopus 로고
    • 17β-estradiol induces nuclear translocation of CrkL at the window of embryo implantation
    • DOI 10.1016/j.bbrc.2004.04.005, PII S0006291X04007107
    • Nautiyal J, Kumar PG, Laloraya M. 17Beta-estradiol induces nuclear translocation of CrkL at the window of embryo implantation. Biochem Biophys Res Commun 2004;318:103-112 (Pubitemid 38526251)
    • (2004) Biochemical and Biophysical Research Communications , vol.318 , Issue.1 , pp. 103-112
    • Nautiyal, J.1    Kumar, P.G.2    Laloraya, M.3
  • 35
    • 0029803854 scopus 로고    scopus 로고
    • Synthesis and characterization of insulin-like growth factor-binding protein (IGFBP)-7: Recombinant human mac25 protein specifically binds IGF-I and -II
    • DOI 10.1074/jbc.271.48.30322
    • Oh Y, Nagalla SR, Yamanaka Y, Kim HS, Wilson E, Rosenfeld RG. Synthesis and characterization of insulin-like growth factor-binding protein (IGFBP)-7. Recombinant human mac25 protein specifically binds IGF-I and -II. J Biol Chem 1996;271:30322-30325 (Pubitemid 26404030)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.48 , pp. 30322-30325
    • Oh, Y.1    Nagalla, S.R.2    Yamanaka, Y.3    Kim, H.-S.4    Wilson, E.5    Rosenfeld, R.G.6
  • 38
    • 0034457886 scopus 로고    scopus 로고
    • Differential regulation of insulin-like growth factor-binding protein-3 protease activity in MCF-7 breast cancer cells by estrogen and transforming growth factor-β1
    • DOI 10.1210/en.141.9.3104
    • Salahifar H, Baxter RC, Martin JL. Differential regulation of insulin-like growth factor-binding protein-3 protease activity in MCF-7 breast cancer cells by estrogen and transforming growth factor-beta1. Endocrinology 2000;141:3104-3110 (Pubitemid 32268997)
    • (2000) Endocrinology , vol.141 , Issue.9 , pp. 3104-3110
    • Salahifar, H.1    Baxter, R.C.2    Martin, J.L.3
  • 39
    • 0033527351 scopus 로고    scopus 로고
    • Mitogenic and antiapoptotic effects of insulin-like growth factor binding protein-6 in the human osteoblastic osteosarcoma cell line Saos-2/B-10
    • DOI 10.1006/bbrc.1999.1451
    • Schmid C, Keller C, Gosteli-Peter M, Zapf J. Mitogenic and antiapoptotic effects of insulin-like growth factor binding protein-6 in the human osteoblastic osteosarcoma cell line Saos-2/B-10. Biochem Biophys Res Commun 1999;263:786-789 (Pubitemid 29490705)
    • (1999) Biochemical and Biophysical Research Communications , vol.263 , Issue.3 , pp. 786-789
    • Schmid, C.1    Keller, C.2    Gosteli-Peter, M.3    Zapf, J.4
  • 40
    • 0036790887 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-6 inhibits neuroblastoma cell proliferation and tumour development
    • Seurin D, Lassarre C, Bienvenu G, Babajko S. Insulin-like growth factor binding protein-6 inhibits neuroblastoma cell proliferation and tumour development. Eur J Cancer 2002;38:2058-2065
    • (2002) Eur J Cancer , vol.38 , pp. 2058-2065
    • Seurin, D.1    Lassarre, C.2    Bienvenu, G.3    Babajko, S.4
  • 41
    • 0025232316 scopus 로고
    • Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: An in situ hybridization study
    • Simerly RB, Chang C, Muramatsu M, Swanson LW. Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study. J Comp Neurol 1990;294:76-95 (Pubitemid 20104631)
    • (1990) Journal of Comparative Neurology , vol.294 , Issue.1 , pp. 76-95
    • Simerly, R.B.1    Chang, C.2    Muramatsu, M.3    Swanson, L.W.4
  • 43
    • 0033305457 scopus 로고    scopus 로고
    • The actions and interactions of sex steroids and growth factors/cytokines on the skeleton
    • Spelsberg TC, Subramaniam M, Riggs BL, Khosla S.The actions and interactions of sex steroids and growth factors/cytokines on the skeleton.Mol Endocrinol 1999;13:819-828
    • (1999) Mol Endocrinol , vol.13 , pp. 819-828
    • Spelsberg, T.C.1    Subramaniam, M.2    Riggs, B.L.3    Khosla, S.4
  • 44
    • 50249097189 scopus 로고    scopus 로고
    • Potential involvement of the interaction between insulin-like growth factor binding protein (IGFBP)-6 and LIM mineralization protein (LMP)-1 in regulating osteoblast differentiation
    • Strohbach C, Kleinman S, Linkhart T, Amaar Y, Chen ST, Mohan S, Strong D. Potential involvement of the interaction between insulin-like growth factor binding protein (IGFBP)-6 and LIM mineralization protein (LMP)-1 in regulating osteoblast differentiation. J Cell Biochem 2008;104:1890-1905
    • (2008) J Cell Biochem , vol.104 , pp. 1890-1905
    • Strohbach, C.1    Kleinman, S.2    Linkhart, T.3    Amaar, Y.4    Chen, S.T.5    Mohan, S.6    Strong, D.7
  • 45
    • 0017581408 scopus 로고
    • The heart: A target organ for estradiol
    • Stumpf WE, Sar M, Aumüller G.The heart: a target organ for estradiol. Science 1977;196:319-321
    • (1977) Science , vol.196 , pp. 319-321
    • Stumpf, W.E.1    Sar, M.2    Aumüller, G.3
  • 47
    • 0034618387 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells
    • Sueoka N, Lee HY, Wiehle S, Cristiano RJ, Fang B, Ji L, Roth JA, Hong WK, Cohen P, Kurie JM. Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells. Oncogene 2000;19:4432-4436 (Pubitemid 30744373)
    • (2000) Oncogene , vol.19 , Issue.38 , pp. 4432-4436
    • Sueoka, N.1    Lee, H.-Y.2    Wiehle, S.3    Cristiano, R.J.4    Fang, B.5    Ji, L.6    Roth, J.A.7    Hong, W.K.8    Cohen, P.9    Kurie, J.M.10
  • 48
    • 0035736013 scopus 로고    scopus 로고
    • Inhibition of human osteoblast marker gene expression by retinoids is mediated in part by insulin-like growth factor binding protein-6
    • DOI 10.1054/ghir.2001.0249
    • Yan T, Wergedal J, Zhou Y, Mohan S, Baylink DJ, Strong DD. Inhibition of human osteoblast marker gene expression by retinoids is mediated in part by insulin-like growth factor binding protein-6. Growth Horm IGF Res 2001;11:368-377 (Pubitemid 34428880)
    • (2001) Growth Hormone and IGF Research , vol.11 , Issue.6 , pp. 368-377
    • Yan, T.1    Wergedal, J.2    Zhou, Y.3    Mohan, S.4    Baylink, D.J.5    Strong, D.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.