Tigecycline for the treatment of multidrug-resistant Klebsiella pneumoniae meningitis

Infectious Diseases in Clinical Practice

Volumn 17, Issue 1, 2009, Pages 66-68

  Dandache, Patricia ^a   Nicolau, David P ^b   Sakoulas, George ^a  

^a WESTCHESTER MEDICAL CENTER   (United States)

^b HARTFORD HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZTREONAM; COLISTIN; MEROPENEM; METRONIDAZOLE; RIFAMPICIN; TETRACYCLINE; TIGECYCLINE; VANCOMYCIN;

ADULT; ARTICLE; BACTERIUM CULTURE; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; DRUG PENETRATION; DRUG SENSITIVITY; GRAM STAINING; HUMAN; KLEBSIELLA PNEUMONIAE; LABORATORY TEST; MALE; MENINGITIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MINIMUM INHIBITORY CONCENTRATION;

EID: 68049114675     PISSN: 10569103     EISSN: None     Source Type: Journal    
DOI: 10.1097/IPC.0b013e318181fa38     Document Type: Article

References (8)

1. Jones ME, Draghi DC, Karlowsky JA, et al. Prevalence of antimicrobial resistance in bacteria isolated from central nervous system specimens as reported by U.S. hospital laboratories from 2000 to 2002. Ann Clin Microbiol Antimicrob. 2004;3(3):1-9.
2. Durand ML, Calderwood SB, Weber DJ, et al. Acute bacterial meningitis in adults. A review of 493 episodes. N Engl J Med. 1993;328(1):21-28.
3. Lu CH, Chang WN, Chuang YC, et al. Gram-negative bacillary meningitis in adult post-neurosurgical patients. Surg Neurol. 1999;52(5):438-443; discussion 443-444.
4. Li C, Sutherland CA, Nightingale CH, et al. Quantitation of tigecycline, a novel glycylcycline by liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2004;811(2):225-229.
5. Bradford PA, Weaver-Sands DT, Petersen PJ. In vitro activity of tigecycline against isolates from patients enrolled in phase 3 clinical trials for complicated skin and skin structure infections and complicated intra-abdominal infections. Clin Infect Dis. 2005;41(suppl 5):S315-S332.
6. Rodvold KA, Gotfried MH, Cwik M, et al. Serum, tissue and body fluid concentrations of tigecycline after a single 100 mg dose. J Antimicrob Chemother. 2006;58(6):1221-1229.
7. Ong CT, Babalola CP, Nightingale CH, et al. Penetration, intracellular accumulation, and efflux of tigecycline in human polymorphonuclear neutrophils (PMNs). J Antimicrob Chemother. 2005;56:498-501.
8. Slover CM, Rodvold KA, Danziger LH. Tigecycline: a novel broad-spectrum antimicrobial. Ann Pharmacother. 2007;41(6):965-972. Epub May 22, 2007.