Intramolecular formal [4 + 2] cycloaddition of nitriles with amides triggered by TMSOTf/Et3N: Highly efficient construction of pyrrolo[1,2-a]-pyrimidin-4(6H)-ones

Journal of Organic Chemistry

Volumn 74, Issue 15, 2009, Pages 5699-5702

  Liu, Feng ^a   Li, Chaozhong ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

[4 + 2] CYCLOADDITION; ACRYLAMIDES; CHEMICAL EQUATIONS; EFFICIENT CONSTRUCTION; HIGH YIELD; KETOAMIDES;

CHEMICAL REACTIONS; CYANIDES; ORGANIC COMPOUNDS;

AMIDES;

2 METHYL 2,3 DIHYDROPYRIMIDO[2,1 A]ISOINDOL 4(6H) ONE; 2,3 DIMETHYLPYRIMIDO[2,1 A]ISOINDOL 4(6H) ONE; AMIDE; ISOINDOLE DERIVATIVE; NITRILE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLOADDITION; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; TEMPERATURE MEASUREMENT;

AMIDES; CYCLIZATION; ETHYLAMINES; MESYLATES; MOLECULAR STRUCTURE; NITRILES; PYRIMIDINONES; PYRROLES; STEREOISOMERISM; TRIMETHYLSILYL COMPOUNDS;

EID: 68049112531     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo900907h     Document Type: Article

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