An improved synthesis of pyridine-thiazole cores of thiopeptide antibiotics

Journal of Organic Chemistry

Volumn 74, Issue 15, 2009, Pages 5750-5753

  Aulakh, Virender S ^a   Ciufolini, Marco A ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

THIOPEPTIDE ANTIBIOTICS;

ANTIBIOTICS;

PYRIDINE;

ANTIBIOTIC AGENT; PYRIDINE DERIVATIVE; THIAZOLE DERIVATIVE; THIOPEPTIDE ANTIBIOTIC DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DECARBOXYLATION; DRUG STRUCTURE; DRUG SYNTHESIS; OXIDATION;

ANTI-BACTERIAL AGENTS; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PEPTIDES; PYRIDINES; STEREOISOMERISM; THIAZOLES;

EID: 68049109443     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo900950x     Document Type: Article

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27. This known compound was made as detailed in the Supporting Information.
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34. Conduct of the reaction in EtOH again failed to produce pyridines.
35. Experimental protocols are provided as Supporting Information.
36. Details of the HPLC analysis are provided as Supporting Information.