Effects of phytoestrogen daidzein and estradiol on steroidogenesis and expression of estrogen receptors in porcine luteinized granulosa cells from large follicles

Journal of Physiology and Pharmacology

Volumn 60, Issue 2, 2009, Pages 95-105

  Nynca, A ^a   Jablonska, O ^a   Slomczynska, M ^b   Petroff, B K ^c   Ciereszko, Renata E ^a  

^a UNIVERSITY OF WARMIA AND MAZURY IN OLSZTYN   (Poland)

^b JAGIELLONIAN UNIVERSITY   (Poland)

^c UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

Daidzein; ER expression; ER expression; Estradiol; Gonadotropins; Granulosa cells; Phytoestrogens; Progesterone; Steroidogenesis

Indexed keywords

DAIDZEIN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GONADOTROPIN; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; EXPERIMENTAL PIG; FEMALE; GRANULOSA CELL; INFERTILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PROGESTERONE RELEASE; PROTEIN EXPRESSION; SOYBEAN; STEROIDOGENESIS; UPREGULATION;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; GENE EXPRESSION; ISOFLAVONES; LUTEAL CELLS; OVARIAN FOLLICLE; PHYTOESTROGENS; PROGESTERONE; RECEPTORS, ESTROGEN; RNA, MESSENGER; SWINE;

EID: 68049107244     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Ciereszko R, Nynca A, Kraszewska O. Phytoestrogen action on the ovary. In The Novel Concepts in Ovarian Endocrinology. A. Gonzalez Bulnes (ed.). Transworld Research Network, Kerala, India, 2007, pp. 303-327.
2. Pocar P, Brevini TAL, Gandolfi F. Environmental influences on ovarian follicle function. In The Novel Concepts in Ovarian Endocrinology. A. Gonzalez (ed.) Bulnes. Transworld Research Network, Kerala, India, 2007, pp. 269-302.
3. Lethaby AE, Brown J, Marjoribanks J, Kronenberg F, Roberts H, Eden J. Phytoestrogens for vasomotor menopausal symptoms. Cochrane Database Syst Rev 2007; 4: Art. No.: CD001395.DOI: 10.1002/14651858.CD001395.pub3.
4. Moutsatsou P. The spectrum of phytoestrogens in nature: our knowledge is expanding. Hormones 2007; 6: 173-193.
5. Szkudelska K, Nogowski L. Genistein - a dietary compound inducing hormonal and metabolic changes. J Steroid Biochem Mol Biol 2007; 105: 37-45. (Pubitemid 47211954)
6. Lu LJW, Anderson KE, Grady JJ, Kohen F, Nagamani M. Decreased ovarian hormones during a soya diet: implications for breast cancer prevention. Cancer Res 2000; 60: 4112-4121. (Pubitemid 30636593)
7. Lu LJW, Anderson KE, Grady JJ, Nagamani M. Effects of soya consumption for one month on steroid hormones in premenopausal women: implications for breast cancer risk reduction. Cancer Epidemiol Biomarkers Prev 1996; 5: 63-70. (Pubitemid 126664211)
8. Wu Z, Yang Y, Chen Y, Xia G, Zhang R. Effects of subcutaneous administration of daidzein on blastocyst implantation in rats. Food Chem Toxicol 2005; 43: 167-172. (Pubitemid 39575744)
9. Parvizi N. Effects of an estrogenic and a non-estrogenic xenobiotic on LH-secretion and reproductive performance in the pig and in the rat. Reprod Domest Anim 1998; 33: 209-211. (Pubitemid 128531359)
10. Tiemann U, Schneider F, Vanselow J, Tomek W. In vitro exposure of porcine granulosa cells to the phytoestrogens genistein and daidzein: Effects on the biosynthesis of reproductive steroid hormones. Reprod Toxicol 2007; 24: 317-325. (Pubitemid 350016767)
11. Mense SM, Hei TK, Ganju RK, Bhat HK. Phytoestrogens and breast cancer prevention: possible mechanisms of action. Environ Health Perspect 2008; 116: 426-433. (Pubitemid 351864298)
12. Nynca A, Kraszewska O, Slomczynska M, Ciereszko R. Phytoestrogens. II. Molecular mechanism of action in female reproductive tract. (in Polish) Adv Cell Biol 2007; 34: 207-222.
13. Ren MQ, Kuhn G, Wegner J, Nurnberg G, Chen J, Ender K. Feeding daidzein to late pregnant sows influences the estrogen receptor beta and type 1 insulin-like growth factor receptor mRNA expression in newborn piglets. J Endocrinol 2001; 170: 129-135. (Pubitemid 32677574)
14. Morito K, Hirose T, Kinjo J et al. Interaction of phytoestrogens with estrogen receptors α and β. Biol Pharm Bull 2001; 24: 351-356.
15. Jefferson WN, Couse JF, Padilla-Banks E, Korach KS, Newbold RR. Neonatal exposure to genistein induces estrogen receptor (ER) α expression and multioocyte follicles in the maturing mouse ovary: evidence for ER β- mediated and nonestrogenic actions. Biol Reprod 2002; 67: 1285-1296.
16. Takashima-Sasaki K, Komiyama M, Adachi T et al. Effect of exposure to high isoflavone-containing diets on prenatal and postnatal offspring mice. Biosci Biotechnol Biochem 2006; 70: 2874-2882. (Pubitemid 46021544)
17. Yuan J-P, Wang J-H, Liu X. Metabolism of dietary soy isoflavones to equol by human intestinal microflora - implications for health. Mol Nutr Food Res 2007; 51: 765-781. (Pubitemid 47173687)
18. Kraszewska O, Nynca A, Kaminska B, Ciereszko R. Phytoestrogens. I. Occurrence, metabolism and biological effects in females. (in Polish) Adv Cell Biol 2007; 34: 189-205.
19. Nynca A, Ciereszko RE. Effect of genistein on steroidogenic response of granulosa cell populations from porcine preovulatory follicles. Reprod Biol 2006; 6: 31-50.
20. Stoklosowa S, Gregoraszczuk E, Channing CP. Estrogen and progesterone secretion by isolated cultured porcine thecal and granulosa cells. Biol Reprod 1982; 26: 943-952.
21. Bannerman DD, Tupper JC, Ricketts WA, Bennet CF, Winn RK, Harlan JM. A constitutive cytoprotective pathway protects endothelial cells from lipopolysaccharide-induced apoptosis. J Biol Chem 2001; 276: 14924-14932. (Pubitemid 37373373)
22. Ciereszko R, Opalka M, Kaminska B, Wojtczak M, Okrasa S, Dusza L. Luteotrophic action of prolactin during the early luteal phase in pigs: the involvement of protein kinases and phosphatases. Reprod Biol 2001; 1: 63-83.
23. Ciereszko R, Petroff BK, Ottobre AC, Guan Z, Stokes BT, Ottobre JS. Assesment of the mechanism by which prolactin stimulates progesterone production by early corpora lutea of pigs. J Endocrinol 1998; 159: 201-209. (Pubitemid 28520171)
24. Szafranska B, Ziecik A, Okrasa S. Primary antisera against selected steroids or proteins and secondary antisera against γ-globulins - an available tool for studies of reproductive processes. Reprod Biol 2002; 2: 187-204.
25. Wong H, Anderson WD, Cheng T, Riabowol KT. Monitoring mRNA expression by polymerase chain reaction: the "primer - dropping" method. Anal Biochem 1994; 223: 251-258.
26. Ciereszko R, Opalka M, Kaminska B, Gorska T, Dusza L. Prolactin signaling in porcine theca cells: involvement of porcine kinases and phosphatases. Reprod Fertil Dev 2003; 15: 27-35. (Pubitemid 36833583)
27. Gregoraszczuk EL, Slomczynska M, Stoklosowa S. Effect of genistein, tyrphostin and herbimycin on prolactin-stimulated progesterone production by porcine theca and luteal cells. J Physiol Pharmacol 1999; 50: 477-484. (Pubitemid 29473107)
28. Whitehead SA, Cross JE, Burden C, Lacey M. Acute and chronic effects of genistein and lavendustin A on steroid synthesis in luteinized human granulosa cells. Hum Reprod 2002; 17: 589-594. (Pubitemid 34232425)
29. Piotrowska KK, Woclawek-Potocka I, Bah MM et al. Phytoestrogens and their metabolites inhibit the sensitivity of the bovine corpus luteum to luteotropic factors. J Reprod Dev 2006; 52: 33-41.
30. Veldhuis JD, Azimi P, Garmey J, Juchter D. Bipotential actions of estrogen on progesterone biosynthesis by ovarian cells. II Realtion of estradiol's stimulatory actions to cholesterol and progestin metabolism in cultured swine granulosa cells. Endocrinology 1985; 117: 1076-1083. (Pubitemid 15020033)
31. Gangrade BK, Davis JS, May JV. Anovel mechanism for the induction of aromatase in ovarian cells in vitro: role of transforming growth factor alpha-induced protein tyrosine kinase. Endocrinology 1991; 129: 2790-2792.
32. Legault S, Bailey JL, Fortier MA, Rouillier P, Guilbault LA. Intracellular regulation of estradiol-17β and progesterone production by cultured bovine granulosa cells. Mol Reprod Dev 1999; 54: 371-378. (Pubitemid 29519866)
33. Myllymaki S, Havisto T, Vainio M, Toppari J, Paranko J. In vitro effects of diethylstilbestrol, genistein, 4-ter-butylphenol, and 4-tert-octyphenol on steroidogenic activity of isolated immature rat ovarian cells. Toxicol Appl Pharmacol 2005; 204: 69-80. (Pubitemid 40392481)
34. Rice S, Mason HD, Whitehead SA. Phytoestrogens and their low dose combinations inhibit mRNA expression and activity of aromatase in human granulosa-luteal cells. J Steroid Biochem Mol Biol 2006; 101: 216-225. (Pubitemid 44592638)
35. Whitehead SA, Lacey M. Phytoestrogens inhibit aromatase but not 17β-hydroxysteroid dehydrogenaze (HSD) type 1 in human granulosa-luteal cells: evidence for FSH induction of 17β-HSD. Hum Reprod 2003; 18: 487-494. (Pubitemid 36329312)
36. Younglai EV, Holloway AC, Lim GE, Foster WG. Synergistic effects between FSH and 1,1-dichloro-2,2-bis(P-chlorophenyl) ethylene (P,P'-DDE) on human granulosa cell aromatase activity. Hum Reprod 2004; 19(5): 1089-1093.
37. Wojtowicz AK, Kajta M, Gregoraszczuk EL. DDT- and DDE-induced disruption of ovarian steroidogenesis in prepubertal porcine ovarian follicles: a possible interaction with the main steroidogenic enzymes and estrogen receptor β. J Physiol Pharmacol 2007; 58(4): 873-885.
38. Makarevich A, Sirotkin A, Taradajnik T, Chrenek P. Effects of genistein and lavendustin on reproductive processes in domestic animals in vitro. J Steroid Biochem Mol Biol 1997; 63: 329-337. (Pubitemid 28137171)
39. Almstrup K, Fernandez MF, Petersen JH, Olea N, Skakkebaek NE, Leffers H. Dual effects of phytoestrogens result in U-shaped dose-response curves. Environ Health Perspect 2002; 110: 743-748. (Pubitemid 34905170)
40. Slomczynska M, Wozniak J. Differential distribution of estrogen receptor-β and estrogen receptor-α in the porcine ovary. Exp Clin Endocrinol Diabetes 2001; 109: 128-244. (Pubitemid 32577692)
41. Pelletier G, Labrie C, Labrie F. Localization of oestrogen receptor α, oestrogen receptor β and androgen receptors in the rat reproductive organs. J Endocrinol 2000; 165: 359-370. (Pubitemid 30341085)
42. Pepe GJ, Billiar RB, Leavitt MG, Zachos NC, Gustafsson JA, Albrecht ED. Expression of estrogen receptors α and β in the baboon fetal ovary. Biol Reprod 2002; 66: 1054-1060.
43. Taylor AH, Al-Azzawi F. Immunolocalisation of estrogen receptor beta in human tissues. J Mol Endocrinol 2000; 24: 145-155. (Pubitemid 30117668)
44. Bao B, Kumar N, Karp RM, Garverick HA, Sundaram K. Estrogen receptor-β expression in relation to the expression of luteinizing hormone receptor and cytochrome P450 enzymes in rat ovarian follicles. Biol Reprod 2000; 63: 1747-1755. (Pubitemid 30954186)
45. Schams D, Berisha B. Steroids as local regulators of ovarian activity in domestic animals. Dom Anim Endocrinol 2002; 23: 53-65. (Pubitemid 34894575)
46. Ptak, A, Ludewig G, Gregoraszczuk EL. A low halogenated biphenyl (PCB3) increases CYP1A1 expression and activity via estrogen receptors β in the porcine ovary. J Physiol Pharmacol 2008; 59: 577-588.
47. Couse JF, Yates MM, Rodriguez KF, Johnson JA, Poirier D, Korach KS. The intraovarian actions of estrogen receptor-a (ERα) are necessary to repress the formation of morphological and functional Leydig-like cells in the female gonad. Endocrinology 2006; 147: 3666-3678. (Pubitemid 44079371)
48. Schomberg DW, Couse JF, Mukherjee A et al. Targeted disruption of the estrogen receptor-a gene in female mice: characterization of ovarian responses and phenotype in the adult. Endocrinology 1999; 140: 2733-2744. (Pubitemid 32245153)
49. Sharma SC, Clemens JW, Pisarska MD, Richards JS. Expression and function of estrogen receptor subtypes in granulosa cells: regulation by estradiol and forskolin. Endocrinology 1999; 140: 4320-4334.
50. Yang P, Kriatchko A, Roy SK. Expression of ER-α and ER- β in the hamster ovary: differential regulation by gonadotropins and ovarian steroid hormones. Endocrinology 2002; 143: 2385-2398. (Pubitemid 34521585)
51. Katzenellenbogen BS, Katzenellenbogen JA. Estrogen receptor transcription and transactivation. Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer. Breast Cancer Res 2000; 2: 335-344.