Network architecture of signaling from uncoupled helicase-polymerase to cell cycle checkpoints and trans-lesion DNA synthesis

Cell Cycle

Volumn 8, Issue 14, 2009, Pages 2281-2299

  Kohn, Kurt W ^a,b   Aladjem, Mirit I ^a   Weinstein, John N ^a   Pommier, Yves ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

ATR; Checkpoints; Claspin; DNA damage; Helicase polymerase uncoupling; Molecular interaction maps; Replication stress; RPA; Signaling network; Trans lesion synthesis

Indexed keywords

ATR PROTEIN; CHECKPOINT KINASE 1; CLASPIN; CYCLIN DEPENDENT KINASE 2; DNA; DNA POLYMERASE; HELICASE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL FUNCTION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CYTOARCHITECTURE; DNA BINDING; DNA DAMAGE; DNA REPLICATION; DNA SYNTHESIS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; GENE SEGREGATION; HUMAN; MOLECULAR INTERACTION; NONHUMAN; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; STRESS; TIGHT JUNCTION;

EID: 68049104164     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.14.9102     Document Type: Article

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