Introduction of the AAL-toxin polyketide synthase gene ALT1 into FUM1-disrupted Fusarium verticillioides produces metabolites with the fumonisin methylation pattern

Journal of Natural Products

Volumn 72, Issue 7, 2009, Pages 1328-1330

  Li, Yaoyao ^a,b   Shen, Yuemao ^b   Zhu, Xiangcheng ^a,c   Du, Liangcheng ^a  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^b XIAMEN UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FUMONISIN; POLYKETIDE SYNTHASE;

ALT1 GENE; ARTICLE; ENZYME ACTIVITY; FUM1 GENE; FUNGAL GENE; FUSARIUM; FUSARIUM VERTICILLIOIDES; NONHUMAN; STEREOCHEMISTRY;

FUMONISINS; FUSARIUM; GENETIC ENGINEERING; METHYLTRANSFERASES; MOLECULAR STRUCTURE; MYCOTOXINS; POLYKETIDE SYNTHASES; STEREOISOMERISM;

FUSARIUM; GIBBERELLA MONILIFORMIS;

EID: 68049102280     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np900193j     Document Type: Article

References (19)

1. Marasas, W. F.; Riley, R. T.; Hendricks, K. A.; Stevens, V. L.; Sadler, T. W.; Gelineau-van Waes, J.; Missmer, S. A.; Cabrera, J.; Torres, O.; Gelderblom, W. C.; Allegood, J.; Martinez, C.; Maddox, J.; Miller, J. D.; Starr, L.; Sullards, M. C.; Roman, A. V.; Voss, K. A.; Wang, E.; Merrill, A. H., Jr. J. Nutr. 2004, 134, 711-716.
2. Nelson, P. E.; Desjardins, A. E.; Plattner, R. D. Annu. Rev. Phytopathol. 1993, 31, 233-252.
3. Gilchrist, D. G.; Grogan, R. G. Phytopathology 1976, 66, 165-171.
4. Bottini, A. T.; Gilchrist, D. G. Tetrahedron Lett. 1981, 22, 2719-2722.
5. Bottini, A. T.; Bowen, J. R.; Gilchrist, D. G. Tetrahedron Lett. 1981, 22, 2723-2726.
6. Brandwagt, B. F.; Mesbah, L. A.; Takken, F. L.; Laurent, P. L.; Kneppers, T. J.; Hille, J.; Nijkamp, H. J. Proc. Natl. Acad. Sci. U.S.A 2000, 97, 4961-4966.
7. Merrill, A. H., Jr.; van Echten, G.; Wang, E.; Sandhoff, K. J. Biol. Chem. 1993, 268, 27299-27306.
8. Riley, R. T.; Wang, E.; Schroeder, J. J.; Smith, E. R.; Plattner, R. D.; Abbas, H.; Yoo, H. S.; Merrill, A. H., Jr. Nat. Toxins 1996, 4, 3-15.
9. Du, L.; Zhu, X.; Gerber, R.; Huffman, J.; Lou, L.; Jorgenson, J.; Yu, F.; Zaleta-Rivera, K.; Wang, Q. J. Ind. Microbiol. Biotechnol. 2008, 35, 455-464.
10. Plattner, R. D.; Shackelford, D. D. Mycopathologia 1992, 117, 17-22.
11. Blackwell, B. A.; Edwards, O. E.; Fruchier, A.; ApSimon, J. W.; Miller, J. D. Adv. Exp. Med. Biol. 1996, 392, 75-91.
12. Branham, B. E.; Plattner, R. D. Mycopathologia 1993, 124, 99-104.
13. Caldas, E. D.; Sadilkova, K.; Ward, B. L.; Jones, A. D.; Winter, C. K.; Gilchrist, D. G. J. Agric. Food Chem. 1998, 46, 4734-4743.
14. Bojja, R. S.; Cerny, R. L.; Proctor, R. H.; Du, L. J. Agric. Food Chem. 2004, 52, 2855-2860.
15. Cox, R. J. Org. Biomol. Chem. 2007, 5, 2010-2026.
16. Proctor, R. H.; Desjardins, A. E.; Plattner, R. D.; Hohn, T. M. Fungal Genet. Biol. 1999, 27, 100-112.
17. Zhu, X.; Vogeler, C.; Du, L. J. Nat. Prod. 2008, 71, 957-960.
18. Gerber, R.; Lou, L.; Du, L. J. Am. Chem. Soc. 2009, 131, 3148-3149.
19. Plattner, D. R.; Weisleder, D.; Shackelford, D. D.; Peterson, R.; Powell, R. G. Mycopathologia 1992, 117, 23-28.