The effects of racemic albuterol versus levalbuterol in very low birth weight infants

Pediatric Pulmonology

Volumn 44, Issue 8, 2009, Pages 778-783

  Mhanna, Maroun J ^a,b   Patel, Jigisha S ^a   Patel, Swati ^a   Cohn, Robert ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b NONE   (United States)

Author keywords

Blood pressure; Heart rate; Infants; Levalbuterol; Premature; Racemic albuterol; Very low birth weight

Indexed keywords

DOBUTAMINE; DOPAMINE; FUROSEMIDE; HYDROCHLOROTHIAZIDE; IPRATROPIUM BROMIDE; LEVALBUTEROL; SALBUTAMOL; STEROID; XANTHINE DERIVATIVE;

ARTICLE; BREATHING RATE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HEART RATE; HEMODYNAMIC PARAMETERS; HUMAN; HYPERGLYCEMIA; HYPOKALEMIA; INFANT; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; MEDICAL RECORD; OXYGEN SATURATION; PRIORITY JOURNAL; RACEMIZATION; VERY LOW BIRTH WEIGHT;

ADRENERGIC BETA-AGONISTS; ALBUTEROL; BLOOD GLUCOSE; BRONCHODILATOR AGENTS; FEMALE; HEMODYNAMICS; HUMANS; INFANT, NEWBORN; INFANT, VERY LOW BIRTH WEIGHT; IPRATROPIUM; MALE; OXIMETRY; POTASSIUM;

EID: 68049101893     PISSN: 87556863     EISSN: 10990496     Source Type: Journal    
DOI: 10.1002/ppul.21056     Document Type: Article

References (30)

1. Wilkie RA, Bryan MH. Effect of bronchodilators on airway resistance in ventilator-dependent neonates with chronic lung disease. J Pediatr 1987;111:278-282.
2. Cabal LA, Larrazabal C, Ramanathan R, Durand M, Lewis D, Siassi B, Hodgman J. Effects of metaproterenol on pulmonary mechanics, oxygenation and ventilation in infants with chronic lung disease. J Pediatr 1987;110:116-119. (Pubitemid 17211896)
3. Kirpalani H, Koren G, Schmidt B, Tan Y, Santos R, Solden S. Respiratory response and pharmacokinetics of intravenous salbutamol in infants with bronchopulmonary dysplasia. Crit Care Med 1990;18:1374-1377.
4. Gappa M, Gartner M, Poets CF, Von der Hardt H. Effects of salbutamol delivery from a metered dose inhaler versus jet nebuliser on dynamic lung mechanics in very preterm infants with chronic lung disease. Pediatr Pulmonol 1997;23:442-448. (Pubitemid 27287501)
5. Fok TF, Lam K, Ng PC, So HK, Cheung KL, Wong W, So HK. Randomised crossover trial of salbutamol aerosol delivered by metered dose inhaler, jet nebuliser and ultrasonic nebuliser in chronic lung disease. Arch Dis Child 1998;79:F100-F104. (Pubitemid 28419168)
6. Rotschild A, Solimano A, Puterman M, Smyth J, Sharma A, Albersheim S. Increased compliance in response to salbutamol in premature infants with developing bronchopulmonary dysplasia. J Pediatr 1989;115:984-991. (Pubitemid 20007089)
7. Kao LC, Durand DJ, Nickerson BG. Effects of inhaled metaproterenol on the pulmonary mechanics of infants with bronchopulmonary dysplasia. Pediatr Pulmonol 1989;6:74-80.
8. Pfenninger J, Aebi C. Respiratory response to salbutamol (albuterol) in ventilator-dependent infants with chronic lung disease: pressurized aerosol delivery versus intravenous injection. Intensive Care Med 1993;19:251-255. (Pubitemid 23265996)
9. Denjean A, Paris-Llado J, Zupan V, Debillon T, Kieffer F, Magny JF, Desfrères L, Llanas B, Guimaraes H, Moriette G, Voyer M, Dehan M, Breart G. Inhaled salbutamol and beclomethasone for preventing broncho-pulmonary dysplasia: a randomised doubleblind study. Eur J Pediatr 1998;157:926-931.
10. Ng GY, da S, Ohlsson A. Bronchodilators for the prevention and treatment of chronic lung disease in preterm infants. Cochrane Database Syst Rev 2001;3:CD003214.
11. Gomez-Del Rio M, Gerhardt T, Hehre D, Feller R, Bancalari E. Effect of a beta-agonist nebulization on lung function in neonates with increased pulmonary resistance. Pediatr Pulmonol 1986;2: 287-291.
12. Denjean A, Guimaraes H, Migdal M, Miramand JL, Dehan M, Gaultier C. Dose-related bronchodilator response to aerosolized salbutamol (albuterol) in ventilator-dependent premature infants. J Pediatr 1992;120:974-979.
13. Lee H, Arnon S, Silverman M. Bronchodilator aerosol administered by metered dose inhaler and spacer in subacute neonatal respiratory distress syndrome. Arch Dis Child 1994;70:218-222. (Pubitemid 24183510)
14. Sivakumar D, Bosque E, Goldman SL. Bronchodilator delivered by metered dose inhaler and spacer improves respiratory system compliance more than nebulizer-delivered bronchodilator in ventilated premature infants. Pediatr Pulmonol 1999;27:208-212. (Pubitemid 29157624)
15. Brudno DS, Parker DH, Slaton G. Response of pulmonary mechanics to terbutaline in patients with bronchopulmonary dysplasia. Am J Med Sci 1989;297:166-168. (Pubitemid 19076947)
16. Fayon M, Tayara N, Germain C, Choukroun ML, De La Roque ED, Chêne G, Breilh D, Marthan R, Demarquez JL. Efficacy and tolerance of high-dose inhaled ipratropium bromide vs. terbutaline in intubated premature human neonates. Neonatology 2007; 91:167-173. (Pubitemid 46481041)
17. Milgrom H, Skoner DP, Bensch G, Kim KT, Claus R, Baumgartner RA. Levalbuterol Pediatric Study Group, Low-dose levalbuterol in children with asthma: safety and efficacy in comparison with placebo and racemic albuterol. J Allergy Clin Immunol 2001;108:938-945. (Pubitemid 33151546)
18. Mhanna MJ, Koester JF, Cohn RC. Effect of (R,R)-formoterol and (R,R/S,S)-formoterol on airway relaxation and contraction in an experimental rat model. Current therapeutic research. Clin Exp 2007;68:249-261.
19. Nelson HS, Bensch G, Pleskow WW, DiSantostefano R, DeGraw S, Reasner DS, Rollins TE, Rubin PD. Improved bronchodilation with levalbuterol compared with racemic albuterol in patients with asthma. J Allergy Clin Immunol 1998;102:943-952. (Pubitemid 29018311)
20. Nowak R, Emerman C, Hanrahan JP, Parsey MV, Hanania NA, Claus R, Schaefer K, Baumgartner RI, Xopenex Acute Severe Asthma Study Group. A comparison of levalbuterol with racemic albuterol in the treatment of acute severe asthma exacerbations in adults. Am J Emerg Med 2006; 24:259-267. (Pubitemid 44316800)
21. Berger WE, Ames DE, Harrison D. A patient satisfaction survey comparing levalbuterol with racemic albuterol in children. Allergy Asthma Proc 2004;25:437-444.
22. Carl JC, Myers TR, Kirchner HL, et al. Comparison of racemic albuterol and levalbuterol for treatment of acute asthma. J Pediatr 2003;143:731-736. (Pubitemid 37510640)
23. Milgrom H, Skoner DP, Bensch G, et al. Low-dose levalbuterol in children with asthma: safety and efficacy in comparison with placebo and racemic albuterol. J Allergy Clin Immunol 2001;108: 938-945. (Pubitemid 33151546)
24. Schreck DM, Babin S. Comparison of racemic albuterol and levalbuterol in the treatment of acute asthma in the ED. Am J Emerg Med 2005;23:842-847. (Pubitemid 41618011)
25. Ralston ME, Euwema MS, Knecht KR, et al. Comparison of levalbuterol and racemic albuterol combined with ipratropium bromide in acute pediatric asthma: a randomized controlled trial. J Emerg Med 2005;29:29-35.
26. Kumar P, Walker JK, Hurt KM, Bennett KM, Grosshans N, Fotis MA. Medication use in the neonatal intensive care unit: current patterns and off-label use of parenteral medications. J Pediatr 2008;152:412-415. (Pubitemid 351231890)
27. Hardasmalani MD, DeBari V, Bithoney WG, et al. Levalbuterol versus racemic albuterol in the treatment of acute exacerbation of asthma in children. Pediatr Emerg Care 2005;21:415-419. (Pubitemid 41061549)
28. Qureshi F, Zaritsky A, Welch C, et al. Clinical efficacy of racemic albuterol versus levalbuterol for the treatment of acute pediatric asthma. Ann Emerg Med 2005;46:29-36. (Pubitemid 40916893)
29. Thompson M, Wise S, Rodeberg H. A preliminary comparison of levalbuterol and albuterol in prehospital care. J Emerg Med 2004; 26:271-277. (Pubitemid 38340824)
30. Schumacher W, Mirkin BL, Sheppard JR. Biological maturation and beta-adrenergic effectors: development of beta-adrenergic receptors in rabbit heart. Mol Cell Biochem 1984;58:173-181.