Cerebroprotective effect of Glycyrrhiza glabra Linn. root extract on hypoxic rats

Bangladesh Journal of Pharmacology

Volumn 4, Issue 1, 2009, Pages 60-64

  Muralidharan, P ^a   Balamurugan, G ^a   Babu, Venu ^a  

^a C L BAID METHA COLLEGE OF PHARMACY   (India)

Author keywords

Cerebroprotective; Glycyrrhiza glabra; Hypoxic; Rat

Indexed keywords

ACETYLCHOLINESTERASE; ALCOHOL; CATALASE; DOPAMINE; GLUTAMIC ACID; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLYCYRRHIZA GLABRA EXTRACT; SODIUM NITRITE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN HYPOXIA; BRAIN LEVEL; BRAIN PROTECTION; CONTROLLED STUDY; DRUG RESPONSE; ENZYME ACTIVITY; MOUSE; NONHUMAN; PLANT ROOT;

EID: 68049097213     PISSN: 1991007X     EISSN: None     Source Type: Journal    
DOI: 10.3329/bjp.v4i1.1052     Document Type: Article

References (26)

1. Aebi H. Catalase In: Methods in enzymatic analysis, Bergmeyer HU (ed), Vol 3. New York, Academic Press, 1983, pp 276-86.
2. Ales H, Norbert Z, Karel S. Changes in diffusion parameters energy related metabolites and glutamate in the rat cortex after transient hypoxia. Neurosci lett. 2006; 404: 137-42. http://dx.doi.org/10.1016/ j.neulet.2006.05.028
3. Ambawade, Kasture KD, Kasturi VS. Anxiolytic activity of Glycyrrhiza glabra Linn. J Nat Remedies. 2001; 2: 130-34.
4. Anonymous. The wealth of India- Raw material, Vol X, (Sp-W), New Delhi, India, Publication and Information Directorate, 1995, p 281.
5. Bernt E, Bergmeyer HU. L-glutamate UV assay with glutamate dehydrogenase and NAD. In: Methods of enzymatic analysis. 2nd ed. New York, Academic Press, 1965, pp 1704-08.
6. Dinesh D, Milind P, Kulkarni SK. Memory enhancing activity of Glycyrrhiza glabra in mice. J Ethnopharmacol. 2004; 91: 361-65. http://dx.doi.org/10.1016/j.jep.2004.01.016
7. Dobler RE, Anderson BM. Simultaneous inactivation of the catalytic activities of yeast glutathione reductase by N-alkyl melimides. Biochem Biophys Acta. 1981; 70: 659.
8. Ecobichon DJ. The basis of toxicology testing. 2nd ed. New York, CRC Press, 1997, pp 43-60.
9. Ellman GL, Courtney KD, Anders U, Feather Stone RM. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol. 1961; 7: 88-95. http://dx.doi.org/10.1016/ 0006-2952(61)90145-9
10. Hirneth H, Classen HG. Inhibition of nitrate-induced increase of plasma nitrite and ethemoglobin in rats by simultaneous feeding of ascorbic acid or tocopherol. Arzneimittelforschung. 1984; 34: 988-91.
11. Holingan S, Jain KL. Effect of glucose concentration on redox status in rat primary cortical neurons under hypoxia. Neurosci Lett. 2006; 410: 57-61. http://dx.doi.org/10.1016/j.neulet.2006.09.066
12. Khare CP (ed). Indian medicinal plants. 1 ed, Berlin, Heidelberg, Springer - Verlag, 2007, pp 289-90.
13. Kokate CK, Purohit AP, Gokhale SB. Analytical pharmacognosy In: Textbook of pharmacognosy. 29th ed. Pune, Nirali Prakasan, 2004, pp 108-09.
14. Lawrence RA, Burk RF. Glutathione peroxidase activity in selenium deficient rat liver. Biochem Biophys Res Comm. 1976; 71: 952-58. http://dx.doi.org/10.1016/0006-291X(76)90747-6
15. Luck H. In: Methods of enzymatic analysis. 2nd ed. New York, Academic Press, 1965, pp 885-90.
16. Marklund S, Marklund G. Involvement of superoxide anion radical in auto-oxidation of pyrogallol and a convenient assay of superoxide dismutase. Eur J Biochem. 1974; 47: 469-74. http://dx.doi.org/10.1111/ j.1432-1033.1974.tb03714.x
17. Morris R. Developments of a water maze procedure for studying spatial learning in the rat. J Neurosci Methods 1984; 11: 47-60. http://dx.doi.org/10.1016/0165-0270(84)90007-4
18. Ravichandra V, Ahalyadevi, Adiga S. Evaluation of the effect of Glycyrrhiza glabra Linn root extract on spatial learning and passive avoidance response in rats. Indian Drugs 2007; 44: 214-19.
19. Schlumpf M, Lichtensteiger W, Langemann H, Waser PG, Hefti F. A fluorimetric micromethod for the simultaneous determination of serotonin, noradrenaline and dopamine in milligram amounts of brain tissue. Biochem Pharmacol. 1974: 23: 2337-46. http://dx.doi.org/ 10.1016/0006-2952(74)90235-4
20. Srinivasan V. Melatonin oxidative stress and neurodegenerative diseases. Indian J Exp Biol. 2002; 40: 668-79.
21. Tao F, Lu SD, Zhang LM, Huang YL. Role of excitatory amino acid transporter in neonatal rat neuronal damage induced by hypoxia. Neuroscience 2001; 102: 503-13. http://dx.doi.org/10.1016/ S0306-4522(00)00485-1
22. Titus ADJ, Harsha HN, Ramkumar K. Hypobaric hypoxia induced dendric atrophy of hippocampal neurons is associated with cognitive impairment in adult rats. Neuroscience 2007; 145: 265-78. http://dx.doi.org/ 10.1016/j.neuroscience.2006.11.037
23. Toshio F, Kazue S, Taro N. Preliminary evaluation of anti nephritis and radical scavenging activities of glabridin from Glycyrrhiza glabra Linn. Fitotherapia. 2003; 74: 624-29. http://dx.doi.org/10.1016/ S0367-326X(03)00164-3
24. Turner RA. Depressants of the central nervous system, In: Screening methods in pharmacology. Turner RA (ed). Vol 1. New York, Academic Press, 1965, pp 69-86.
25. Vaya J, Belinky PA, Aviram M. Structural aspects of the inhibitory effect of glabridin on LDL oxidation. Free Rad Biol Med. 1998; 24: 1419-29. http://dx.doi.org/10.1016/S0891-5849(98)00006-9
26. Zhan C, Yang J. Protective effects of isoliquiritigenin in transient middle cerebral artery occlusion induced focal cerebral ischemia in rats. Pharmacol Res. 2006; 53: 303-09. http://dx.doi.org/10.1016/ j.phrs.2005.12.008