Two salonitenolide derivatives from the aerial parts of Centaurea gigantea inhibit the growth of colorectal cancer cells in vitro

Natural Product Communications

Volumn 2, Issue 2, 2007, Pages 121-125

  Shoeb, Mohammad ^a   Celik, Sezgin ^b   Nahar, Lutfun ^c   MacManus, Stephen M ^c   Kong Thu Lin, Paul ^c   Jaspars, Marcel ^d   Sarker, Satyajit D ^e  

^a UNIVERSITY OF DHAKA   (Bangladesh)

^b ÇANAKKALE ONSEKIZ MART UNIVERSITY   (Turkey)

^c ROBERT GORDON UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF ABERDEEN   (United Kingdom)

^e UNIVERSITY OF ULSTER   (United Kingdom)

Author keywords

8 O (3 hydroxy 2 methylpropanoyl) sa) onitenolide; 8 O (4 hydroxy 3 melhylbutanoy ) salonitenolide; Asteraceae; Brine shrimp lethality assay; Centaurea gigantea; Colon cancer; DPPH assay; MTT

Indexed keywords

EID: 68049085850     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: 10.1177/1934578x0700200202     Document Type: Article

References (17)

1. American Cancer Society. (2006) Cancer reference information. Available on-line at: http://www.cancer.org/docroot/home/index.asp?level=0
2. Cancer Research UK. (2005) Statistics: cancer facts and figures. Available on-line at http://www.cancerresearchuk.org/ aboutcancer/statistics/
3. Shoeb M, Celik S, Jaspars M, Kumarasamy Y, MacManus SM, Nahar L, Thoo-Lin PK, Sarker SD. (2005) Isolation, structure elucidation and bioactivity of schischkiniin, a unique indole alkaloid from the seeds of Centaurea schischkini. Tetrahedron, 61, 9001-9006.
4. Shoeb M, MacManus SM, Jaspars M, Trevidadu J, Nahar L, Kong-Thoo-Lin P, Sarker SD. (2006) Montamine, a unique dimeric indole alkaloid, from the seeds of Centaurea montana (Asteraceae), and its in vitro cytotoxic activity against the CaCo2 colon cancer cells. Tetrahedron (in press).
5. Kumarasamy Y, Nahar L, Kong-Thoo-Lin P, Jaspars M, Sarker SD. (2006) Hederacine A and hederacine B from Glechoma hederacea inhibit the growth of colorectal cancer cells in vitro. Natural Product Communications, 1, 33-35.
6. Mossman T. (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays, Journal of lmmunological Methods, 65, 55-63.
7. Takao T, Watanabe N, Yagi I, Sakata K. (1994) A simple screening method for antioxidants and isolation of several antioxidants produced by marine bacteria from fish and shellfish. Bioscience, Biotechnology and Biochemistry, 58, 1780-1783.
8. Meyer BN, Ferrigni RN, Putnam JE, Jacobsen LB, Nichols DE, Mclaughlin JL. (1982) Brine shrimp- A convenient general bioassay for active plants constituents. Planta Medica, 45, 31-34.
9. Wagentiz, G. (1975) In Flora of Turkey and the East Aegean Islands, Davis, PH, Ed, University Press, Edinburgh.
10. Sarker SD, Savchenko T, Whiting P, Sik V, Dinan LN. (1997) Moschamine, cis-moschamine, moschamine, moschamindole and moschamindolol: four novel indole alkaloids from Centaurea moschata. Natural Product Letters, 9, 189-199.
11. Medjroubi K, Benayache F, Benayache S, Akkal S, Khalfallah N, Aclinou P. (1997) Guaianolides from Centaurea musimomum. Phytochemistry, 45, 1449-1451.
12. Pavia DL. (2001) Introduction to spectroscopy, A guide for students of Organic Chemistry, Fort Worth, TX: Harcourt College.
13. Barrero AF, Sanchez JF, Rodriguez I. (1989) Germacranolides from Centaurea melitensis. Phytochemistry, 28, 1975-1976.
14. Lazari D, Garcia B, Skaltsa H, Pedro JR, Harvala C. (1998) Sesquiterpene lactones from Onopordon laconicum and O. sihthorpianum. Phytochemistry, 47, 415-422.
15. Kumarasamy Y, Fergusson M, Nahar L, Sarker SD. (2002) Biological activity of moschamindole from Centaurea moschata. Pharmaceutical Biology, 40, 307-310.
16. Uddin SJ, Shilpi JA, Delazar A, Nahar L, Sarker SD. (2004) Free radical scavenging activity of some Bangladeshi plant extracts. Oriental Pharmacy and Experimental Medicine, 4, 185-193.
17. Finney DJ. (1971) Probit Analysis, 3rd ed., Cambridge University Press, Cambridge.