Recombinant factor XIII diminishes multiple organ dysfunction in rats caused by gut ischemia-reperfusion injury

Shock

Volumn 31, Issue 6, 2009, Pages 621-626

  Zaets, Sergey B ^a   Xu, Da Zhong ^b   Lu, Qi ^b   Feketova, Eleonora ^b   Berezina, Tamara L ^b   Gruda, Maryann ^a   Malinina, Inga V ^a   Deitch, Edwin A ^b   Olsen, Eva H N ^a  

^a NOVO NORDISK INC   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Fibrin stabilizing factor; Lung injury; Microcirculatory disorders; Oxidative stress; Superior mesenteric artery occlusion

Indexed keywords

BLOOD CLOTTING FACTOR 13; FIBRIN; MYELOPEROXIDASE; PLACEBO; RECOMBINANT BLOOD CLOTTING FACTOR 13 A 2 SUBUNIT; RECOMBINANT PROTEIN; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING; BLOOD FLOW; CONTROLLED STUDY; DOSE RESPONSE; ENDOTHELIUM CELL; ENZYME ACTIVITY; EXPERIMENTAL MODEL; FIBRIN CLOT; HISTOPATHOLOGY; ILEUM MUCOSA; IN VITRO STUDY; INTESTINE ISCHEMIA; LIVER; LUNG; MALE; MULTIPLE ORGAN FAILURE; MUSCLE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PERMEABILITY; PLASMA FACTOR; RAT; REPERFUSION INJURY; RESPIRATORY BURST; SHAM PROCEDURE; SUPERIOR MESENTERIC ARTERY OBSTRUCTION; THERAPY EFFECT; TISSUE OXYGENATION; TREATMENT OUTCOME; TREATMENT RESPONSE; UMBILICAL VEIN;

ANIMALS; CELL MEMBRANE PERMEABILITY; ENZYME ACTIVATION; FACTOR XIII; GASTROINTESTINAL TRACT; HUMANS; LUNG; MALE; MESENTERIC ARTERY, SUPERIOR; MICROCIRCULATION; MULTIPLE ORGAN FAILURE; NEUTROPHILS; PEROXIDASE; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; REGIONAL BLOOD FLOW; REPERFUSION INJURY; RESPIRATORY BURST;

EID: 68049084830     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e31818bbe21     Document Type: Article

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