Enzymatic synthesis of C-terminal arylamides of amino acids and peptides

Journal of Organic Chemistry

Volumn 74, Issue 15, 2009, Pages 5145-5150

  Nuijens, Timo ^a,b   Cusan, Claudia ^a   Kruijtzer, John A W ^b   Rijkers, Dirk T S ^b   Liskamp, Rob M J ^b   Quaedflieg, Peter J L M ^a  

^a DSM Pharmaceutical Products   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALCALASE; ANHYDROUS CONDITIONS; ANILIDES; ARYL AMIDE; ARYL SUBSTITUENTS; CHEMICAL EQUATIONS; CHEMICAL METHOD; CHEMO-ENZYMATIC SYNTHESIS; COST-EFFICIENT; CYSTEINE PROTEASE; DIASTEREOMERIC PURITY; ELECTRON-WITHDRAWING SUBSTITUENTS; ENANTIO; ENZYMATIC METHODS; ENZYMATIC SYNTHESIS; HIGH YIELD; SERINE PROTEASE; SIDE-CHAIN FUNCTIONALITIES;

AMIDES; AMINATION; AMINO ACIDS; CARBOXYLIC ACIDS; ESTERS; ORGANIC ACIDS; PEPTIDES; SUBSTITUTION REACTIONS;

AMINES;

AMINO ACID DERIVATIVE; ANILINE; AROMATIC AMIDE; BENZYL DERIVATIVE; CARBOXYL GROUP; CARBOXYLIC ACID DERIVATIVE; CYSTEINE PROTEINASE; DIPEPTIDE; ESTER DERIVATIVE; GUANIDINE DERIVATIVE; PAPAIN; PEPTIDE DERIVATIVE; SERINE PROTEINASE; SUBTILISIN; TRIACYLGLYCEROL LIPASE;

ARTICLE; CATALYSIS; DIASTEREOISOMER; ENANTIOSELECTIVITY; ENZYME SYNTHESIS; PROTEIN STRUCTURE; RACEMIZATION;

AMIDES; AMINO ACIDS; ANILIDES; BACILLUS; LIPASE; MOLECULAR CONFORMATION; PAPAIN; PEPTIDES; STEREOISOMERISM; SUBTILISINS;

EID: 68049084768     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo900634g     Document Type: Article

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