Can Protocol Biopsy Better Inform Our Choices in Renal Transplantation?

Transplantation Proceedings

Volumn 41, Issue 6 SUPPL., 2009, Pages

  Rush, D ^a  

^a HEALTH SCIENCES CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; TACROLIMUS;

ARTICLE; BIOPSY; CLINICAL PRACTICE; GENOMICS; GRAFT DYSFUNCTION; GRAFT FAILURE; GRAFT RECIPIENT; GRAFT REJECTION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY ALLOGRAFT; KIDNEY INJURY; KIDNEY TRANSPLANTATION; METABOLOMICS; MORBIDITY; PATIENT SAFETY; PREVALENCE; PRIORITY JOURNAL; PROTEOMICS; RISK REDUCTION; SAMPLING ERROR;

BIOPSY; CYCLOSPORINE; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFLAMMATION; KIDNEY; KIDNEY TRANSPLANTATION; URINE;

EID: 67949117038     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2009.06.092     Document Type: Article

References (22)

1. Vincenti F., Schena F.P., Paraskevas S., et al. A randomized, multicentre study of steroid avoidance, early steroid withdrawal or standard steroid therapy in kidney transplant recipients. Am J Transplant 8 (2008) 307
2. Ekberg H., Grinyó J., Nashan B., et al. Cyclosporine sparing with mycophenolate mofetil, daclizumab and corticosteroids in renal allograft recipients: the CAESAR Study. Am J Transplant 7 (2007) 560
3. Opelz G., and Döhler B. Effect on kidney graft survival of reducing or discontinuing maintenance immunosuppression after the first year posttransplant. Transplantation 86 (2008) 371
4. El-Zoghby Z.M., Stegall M.D., Lager D.J., et al. Identifying specific causes of kidney allograft loss. Am J Transplant 9 (2009) 527
5. Solez K., Axelsen R.A., Benediktsson H., et al. International standardization of criteria for the histologic diagnosis of renal allograft rejection: the Banff working classification of kidney transplant pathology. Kidney Int 44 (1993) 411
6. Rush D., Nickerson P., Gough J., et al. Beneficial effects of treatment of early subclinical rejection: a randomized study. J Am Soc Nephrol 9 (1998) 2129
7. Kurtkoti J, Sakhuja V, Sud K, et al: The utility of 1- and 3-month protocol biopsies on renal allograft function: a randomized controlled study.
8. Nankivell B.J., Borrows R.J., Fung C.L., et al. Natural history, risk factors and impact of subclinical rejection in kidney transplantation. Transplantation 78 (2004) 242
9. Rush D., Arlen D., Boucher A., et al. Lack of benefit of early protocol biopsies in renal transplant patients receiving TAC and MMF: a randomized study. Am J Transplant 7 (2007) 2538
10. Mengel M., Gwinner W., Schwarz A., et al. Infiltrates in protocol biopsies from renal allografts. Am J Transplant 7 (2007) 356
11. Moreso F., Ibernón M., Goma M., et al. Subclinical rejection associated with chronic allograft nephropathy in protocol biopsies as a risk factor for late graft loss. Am J Transplant 6 (2006) 747
12. Cosio F.G., Grande J.P., Wadei H., et al. Predicting subsequent decline in kidney allograft function from early surveillance biopsies. Am J Transplant 5 (2005) 2464
13. Hoffmann S.C., Hale D.A., Kleiner D.E., et al. Functionally significant renal allograft rejection is defined by transcriptional criteria. Am J Transplant 5 (2005) 573
14. Bestard O., Cruzado J.M., Rama I., et al. Presence of FoxP3+ regulatory T cells predicts outcome of subclinical rejection of renal allografts. J Am Soc Nephrol 19 (2008) 2020
15. Schaub S., Rush D., Wilkins J., et al. Proteomic-based detection of urine proteins associated with acute renal allograft rejection. J Am Soc Nephrol 15 (2004) 219
16. 2-microglobulin as a potential marker for acute tubular injury in renal allografts. Am J Transplant 5 (2005) 729
17. Schaub S., Mayr M., Hönger G., et al. Detection of subclinical tubular injury after renal transplantation: comparison of urine protein analysis with allograft histopathology. Transplantation 84 (2007) 104
18. Foxall P.J., Mellotte G.J., Bending M.R., et al. MR spectroscopy as a novel approach to the monitoring of renal transplant function. Kidney Int 28 (1993) 234
19. Le Moyec L., Pruna A., Eugene M., et al. Proton nuclear magnetic resonance spectroscopy of urine and plasma in renal transplantation. Nephron 65 (1993) 433
20. Rush D., Somorjai R., Deslauriers R., et al. Subclinical rejection-a potential surrogate marker for chronic rejection-may be diagnosed by protocol biopsy or urine spectroscopy. Ann Transplant 5 (2000) 44
21. Rush D., Somorjai R., Cecka M., et al. Urine magnetic resonance spectroscopy (UMRS): preliminary observations in the deterioration of kidney allograft function (DeKAF) study. Transplantation 86 (2008) 262
22. Schaub S, Nickerson P, Rush D, et al: Urinary CXCL9 and CXCL10 levels correlate with the extent of subclinical tubulitis. Am J Transplant (in press)