Polymorphism/loss of heterozygosity of APC gene in GERD-Barrett's metaplasia-dysplasia-adenocarcinoma sequence;Polimorfizm/utrata heterozygotyczności genu APC w sekwencji GERD-przełyk Barretta-dysplazja-rak gruczołowy przełyku

Polski Merkuriusz Lekarski

Volumn 26, Issue 155, 2009, Pages 385-389

  Mokrowiecka, Anna ^a   Wierzchniewska Ławska, Agnieszka ^a   Smolarz, Beata ^b,c   Romanowicz Makowska, Hanna ^b,c   Małecka Panas, Ewa ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b Pracownia Biologii Molekularnej   (Poland)

^c Institute of the Polish Mothers Memorial Hospital in ó d   (Poland)

Author keywords

APC gene; Barrett's esophagus; Loss of heterozygosity

Indexed keywords

TUMOR MARKER;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; BARRETT ESOPHAGUS; DISEASE COURSE; ESOPHAGUS; ESOPHAGUS TUMOR; FEMALE; GASTROESOPHAGEAL REFLUX; GENETIC POLYMORPHISM; GENETICS; HETEROZYGOSITY LOSS; HETEROZYGOTE; HUMAN; HYPERPLASIA; MALE; METAPLASIA; MIDDLE AGED; PATHOLOGY; PRECANCER; STOMACH MUCOSA; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; ADULT; AGED; BARRETT ESOPHAGUS; DISEASE PROGRESSION; ESOPHAGEAL NEOPLASMS; ESOPHAGUS; FEMALE; GASTRIC MUCOSA; GASTROESOPHAGEAL REFLUX; GENES, APC; HETEROZYGOTE; HUMANS; HYPERPLASIA; LOSS OF HETEROZYGOSITY; MALE; METAPLASIA; MIDDLE AGED; POLYMORPHISM, GENETIC; PRECANCEROUS CONDITIONS; TUMOR MARKERS, BIOLOGICAL;

EID: 67949092898     PISSN: 14269686     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Bektas N., Donner A., Wirtz C. i wsp.: Allelic loss involving the tumor suppressor genes APC and MCC and expression of the APC protein in the development of dysplasia and carcinoma in Barrett esophagus. Am. J. Clin. Pathol., 2000, 114, 890-895.
2. Bian Y.S., Osterheld M.C., Bosman FT. i wsp.: Nuclear Accumulation of beta-Catenin Is a Common and Early Event During Neoplastic Progression of Barrett Esophagus. Am. J. Clin. Pathol., 2000, 114, 583-90.
3. Boynton R.F., Blount P.I., Yin J. i wsp.: Loss of heterozygosity involving the APC and MCC genetic loci occurs in the majority of human esophageal cancers. Proc. Natl. Acad. Sci. USA., 1992, 89, 3385-3388.
4. Clement G., Braunschweig R., Pasquier N. i wsp.: Alterations of the Wnt signaling pathway during the neoplastic progression of Barrett's esophagus. Oncogene., 2006, 25, 3084-3092.
5. Cook M.B., Greenwood D.C., Hardie L.J.: A systematic review and metaanalysis of the risk of increasing adiposity on Barrett's esophagus. Am.J.Gastroenterol.,2008, 103, 292-300.
6. Dolan K., Garde J., Walker S.J. i wsp.: LOH at the sites of the DCC, APC, and TP53 tumor suppressor genes occurs in Barrett's mataplasia and dysplasia adjacent to adenocarcinoma of the esophagus. Hum. Pathol., 1999, 30, 1508-1514.
7. Gonzalez M.V., Artimez M.L., Rodrigo L. i wsp.: Mutation analysis of the p53, APC, and p 16 genes in the Barrett's oesophagus, dysplasia, and adenocarcinoma. J. Clin. Pathol., 1997, 50, 212-217.
8. Lamparska-Przybysz M., Wieczorek M., Majorek M. i wsp.: Rola szlaku Wnt/beta-katenina w molekularnym mechanizmie procesów nowotworowych. Współczesna Onkologia, 2006, 10, 497-501.
9. Lin J., Beer D.G.: Molecular biology of upper gastrointestinal malignancies. Seminars in Oncology, 2004, 31, 476-486.
10. Marsman W.A., Birjmohun R.S., van Rees B.P. i wsp.: Loss of Heterozygosity and Immunohistochemistry of Adenocarcinomas of the Esophagus and Gastric Cardia. Clinical Cancer Research,2004,10, 8479-8485.
11. Pasz-Walczak G., Jesionek-Kupnicka D., Kubiak R. i wsp.: Podstawowe mechanizmy kancerogenezy w jelicie grubym. Współczesna Onkologia, 2004, 8, 303-307.
12. Pecina-Slaus N., Nikuseva Martic T., Tomas D. i wsp.: Meningiomas exhibit loss of heterozygosity of the APC gene. J. Neurooncol., 2008, 87, 63-70.
13. Plawski A., Słomski R.: APC gene mutations causing familial adenomatous polyposis in Polish patients. J. Appl. Genet., 2008, 49, 407-414.
14. Raja S., Finkelstein S.D., Baksh F.K. i wsp.: Correlation between dysplasia and mutations of six tumor suppressor genes in Barrett's esophagus. Ann. Thorac. Surg., 2001, 72, 1130-1135.
15. Reid B.J., Prevo L.J., Galipeau P.C.: Predictors of progression in Barrett's esophagus II: Baseline 17 p (p53) loss of heterozygosity identifies a patient subset at increased risk for neoplastic progression. Am.J.Gastro-enterol., 2001, 96, 2839-2848.
16. Romagnoli S., Roncalli M., Graziani D. i wsp.: Molecular alterations of Barrett's esophagus on microdissected endoscopic biopsies. Laboratory Investigation, 2001, 81, 241-247.
17. Tandle A., Sanghavi V., Saranath D.: Infrequent loss of heterozygosity at adenomatous polyposis coli gene locus in India oral cancers. Cancer Lett., 2000, 157, 155-160.
18. Wijnhoven B.P.L., Tilanus H.W., Dinjens W.N.M.: Molecular biology of Barrett's adenocarcinoma. Annals of Surgery, 2001, 233, 322-337.
19. Wu T.T., Watanabe T., Heitmiller R. i wsp.: Genetic alterations in Barrett esophagus and adenocarcinomas of the esophagus and esophagogastric junction region. Am. J. Pathol., 1998, 153, 287-294.
20. Zhuang Z., Vortmeyer A.O., Mark E.J. i wsp.: Barrett's esophagus: metaplastic cells with loss of heterozygosity at the APC gene locus are clonal precursors to invasive adenocarcinoma. Cancer Research,1996, 56, 1961-1964.