-
1
-
-
54849146500
-
Clinical practice. Autosomal dominant polycystic kidney disease
-
Grantham J.J. Clinical practice. Autosomal dominant polycystic kidney disease. N Engl J Med 359 (2008) 1477
-
(2008)
N Engl J Med
, vol.359
, pp. 1477
-
-
Grantham, J.J.1
-
3
-
-
36749046442
-
Molecular pathogenesis of ADPKD and development of targeted therapeutic options
-
Ibraghimov-Beskrovnaya O. Molecular pathogenesis of ADPKD and development of targeted therapeutic options. Nephrol Dial Transplant 22 (2007) 3367
-
(2007)
Nephrol Dial Transplant
, vol.22
, pp. 3367
-
-
Ibraghimov-Beskrovnaya, O.1
-
4
-
-
34047276812
-
Autosomal dominant polycystic kidney disease
-
Torres V.E., Harris P.C., and Pirson Y. Autosomal dominant polycystic kidney disease. Lancet 369 (2007) 1287
-
(2007)
Lancet
, vol.369
, pp. 1287
-
-
Torres, V.E.1
Harris, P.C.2
Pirson, Y.3
-
5
-
-
44349084391
-
Vasopressin antagonists in polycystic kidney disease
-
Torres V.E. Vasopressin antagonists in polycystic kidney disease. Semin Nephrol 28 (2008) 306
-
(2008)
Semin Nephrol
, vol.28
, pp. 306
-
-
Torres, V.E.1
-
6
-
-
33645762033
-
mTOR is out of control in polycystic kidney disease
-
Mostov K.E. mTOR is out of control in polycystic kidney disease. Proc Natl Acad Sci U S A 103 (2006) 5247
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 5247
-
-
Mostov, K.E.1
-
7
-
-
33645769011
-
The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease
-
Shillingford J.M., Murcia N.S., Larson C.H., et al. The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease. Proc Natl Acad Sci U S A 103 (2006) 5466
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 5466
-
-
Shillingford, J.M.1
Murcia, N.S.2
Larson, C.H.3
-
8
-
-
18744380752
-
Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease
-
Tao Y., Kim J., Schrier R.W., et al. Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease. J Am Soc Nephrol 16 (2005) 46
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 46
-
-
Tao, Y.1
Kim, J.2
Schrier, R.W.3
-
9
-
-
33644859253
-
Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD)
-
Wahl P.R., Serra A.L., Le Hir M., et al. Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD). Nephrol Dial Transplant 2 (2006) 598
-
(2006)
Nephrol Dial Transplant
, vol.2
, pp. 598
-
-
Wahl, P.R.1
Serra, A.L.2
Le Hir, M.3
-
10
-
-
34447514158
-
Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease
-
Wu M., Wahl P.R., Le Hir M., et al. Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease. Kidney Blood Press Res 30 (2007) 253
-
(2007)
Kidney Blood Press Res
, vol.30
, pp. 253
-
-
Wu, M.1
Wahl, P.R.2
Le Hir, M.3
-
11
-
-
33745621035
-
Therapeutic approaches in autosomal dominant polycystic kidney disease (ADPKD): is there light at the end of the tunnel?
-
Walz G. Therapeutic approaches in autosomal dominant polycystic kidney disease (ADPKD): is there light at the end of the tunnel?. Nephrol Dial Transplant 21 (2006) 1752
-
(2006)
Nephrol Dial Transplant
, vol.21
, pp. 1752
-
-
Walz, G.1
-
12
-
-
0034959984
-
Angiogenesis in autosomal-dominant polycystic kidney disease
-
Bello-Reuss E., Holubec K., and Rajaraman S. Angiogenesis in autosomal-dominant polycystic kidney disease. Kidney Int 60 (2001) 37
-
(2001)
Kidney Int
, vol.60
, pp. 37
-
-
Bello-Reuss, E.1
Holubec, K.2
Rajaraman, S.3
-
13
-
-
33748943989
-
Evidence of angiogenesis and microvascular regression in autosomal-dominant polycystic kidney disease kidneys: a corrosion cast study
-
Wei W., Popov V., Walocha J.A., et al. Evidence of angiogenesis and microvascular regression in autosomal-dominant polycystic kidney disease kidneys: a corrosion cast study. Kidney Int 70 (2006) 1261
-
(2006)
Kidney Int
, vol.70
, pp. 1261
-
-
Wei, W.1
Popov, V.2
Walocha, J.A.3
-
14
-
-
34247864018
-
Involvement of hypoxia-inducible transcription factors in polycystic kidney disease
-
Bernhardt W.M., Wiesener M.S., Weidemann A., et al. Involvement of hypoxia-inducible transcription factors in polycystic kidney disease. Am J Pathol 170 (2007) 830
-
(2007)
Am J Pathol
, vol.170
, pp. 830
-
-
Bernhardt, W.M.1
Wiesener, M.S.2
Weidemann, A.3
-
15
-
-
42449089027
-
Sirolimus ameliorates the enhanced expression of metalloproteinases in a rat model of autosomal dominant polycystic kidney disease
-
Berthier C.C., Wahl P.R., Le Hir M., et al. Sirolimus ameliorates the enhanced expression of metalloproteinases in a rat model of autosomal dominant polycystic kidney disease. Nephrol Dial Transplant 23 (2008) 880
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 880
-
-
Berthier, C.C.1
Wahl, P.R.2
Le Hir, M.3
-
16
-
-
0036174289
-
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor
-
Guba M., von Breitenbuch P., Steinbauer M., et al. Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor. Nat Med 8 (2002) 128
-
(2002)
Nat Med
, vol.8
, pp. 128
-
-
Guba, M.1
von Breitenbuch, P.2
Steinbauer, M.3
-
17
-
-
35748948350
-
Clinical proof-of-concept trial to assess the therapeutic effect of sirolimus in patients with autosomal dominant polycystic kidney disease: SUISSE ADPKD study
-
Serra A.L., Kistler A.D., Poster D., et al. Clinical proof-of-concept trial to assess the therapeutic effect of sirolimus in patients with autosomal dominant polycystic kidney disease: SUISSE ADPKD study. BMC Nephrol 8 (2007) 13
-
(2007)
BMC Nephrol
, vol.8
, pp. 13
-
-
Serra, A.L.1
Kistler, A.D.2
Poster, D.3
-
18
-
-
0020569860
-
Rate of functional deterioration in polycystic kidney disease
-
Franz K.A., and Reubi F.C. Rate of functional deterioration in polycystic kidney disease. Kidney Int 23 (1983) 526
-
(1983)
Kidney Int
, vol.23
, pp. 526
-
-
Franz, K.A.1
Reubi, F.C.2
-
19
-
-
33646678189
-
Volume progression in polycystic kidney disease
-
CRISP Investigators
-
Grantham J.J., Torres V.E., Chapman A.B., et al., CRISP Investigators. Volume progression in polycystic kidney disease. N Engl J Med 354 (2006) 2122
-
(2006)
N Engl J Med
, vol.354
, pp. 2122
-
-
Grantham, J.J.1
Torres, V.E.2
Chapman, A.B.3
-
20
-
-
58149171924
-
Increases in kidney volume in autosomal dominant polycystic kidney disease can be detected within 6 months
-
Kistler A.D., Poster D., Krauer F., et al. Increases in kidney volume in autosomal dominant polycystic kidney disease can be detected within 6 months. Kidney Int 75 (2009) 235
-
(2009)
Kidney Int
, vol.75
, pp. 235
-
-
Kistler, A.D.1
Poster, D.2
Krauer, F.3
-
21
-
-
33646710257
-
Volume progression in autosomal dominant polycystic kidney disease: the major factor determining clinical outcomes
-
Grantham J.J., Chapman A.B., and Torres V.E. Volume progression in autosomal dominant polycystic kidney disease: the major factor determining clinical outcomes. Clin J Am Soc Nephrol 1 (2006) 148
-
(2006)
Clin J Am Soc Nephrol
, vol.1
, pp. 148
-
-
Grantham, J.J.1
Chapman, A.B.2
Torres, V.E.3
-
22
-
-
40449138290
-
Sirolimus reduces polycystic liver volume in ADPKD patients
-
Qian Q., Du H., King B.F., et al. Sirolimus reduces polycystic liver volume in ADPKD patients. J Am Soc Nephrol 19 (2008) 631
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 631
-
-
Qian, Q.1
Du, H.2
King, B.F.3
-
23
-
-
27644436740
-
Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies
-
Kauffman H.M., Cherikh W.S., Cheng Y., et al. Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies. Transplantation 80 (2005) 883
-
(2005)
Transplantation
, vol.80
, pp. 883
-
-
Kauffman, H.M.1
Cherikh, W.S.2
Cheng, Y.3
|