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Volumn 10, Issue , 2009, Pages

Bilobalide modulates serotonin-controlled behaviors in the nematode Caenorhabditis elegans

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; AMYLOID BETA PROTEIN; BILOBALIDE; DOPAMINE; MUTANT PROTEIN; PROTEIN MOD1; PROTEIN SER4; SEROTONIN; SEROTONIN RECEPTOR; TRYPTOPHAN HYDROXYLASE; UNCLASSIFIED DRUG; ALDICARB; CAENORHABDITIS ELEGANS PROTEIN; CHLORIDE CHANNEL; CHOLINESTERASE INHIBITOR; CYCLOPENTANE DERIVATIVE; FURAN DERIVATIVE; GINKGOLIDE; MOD 1 PROTEIN, C ELEGANS; MOD-1 PROTEIN, C ELEGANS; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE; SEROTONIN ANTAGONIST;

EID: 67949083609     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-10-62     Document Type: Article
Times cited : (15)

References (42)
  • 1
    • 4544328810 scopus 로고    scopus 로고
    • BDNF and 5-HT: A dynamic duo in age-related neuronal plasticity and neurodegenerative disorders
    • 15374669
    • Mattson MP Maudsley S Martin B BDNF and 5-HT: A dynamic duo in age-related neuronal plasticity and neurodegenerative disorders Trends Neurosci 2004, 27:589-94 10.1016/j.tins.2004.08.001 15374669
    • (2004) Trends Neurosci , vol.27 , pp. 589-594
    • Mattson, M.P.1    Maudsley, S.2    Martin, B.3
  • 2
    • 0034100397 scopus 로고    scopus 로고
    • Role of serotonin in memory impairment
    • 10.3109/07853890008998828 10821328
    • Buhot MC Martin S Segu L Role of serotonin in memory impairment Ann Med 2000, 32:210-21 10.3109/07853890008998828 10821328
    • (2000) Ann Med , vol.32 , pp. 210-221
    • Buhot, M.C.1    Martin, S.2    Segu, L.3
  • 3
    • 0026664554 scopus 로고
    • Animal and drug modelling for Alzheimer synaptic pathology
    • 10.1016/0301-0082(92)90005-Y 1529103
    • Francis PT Pangalos MN Bowen DM Animal and drug modelling for Alzheimer synaptic pathology Prog Neurobiol 1992, 39:517-45 10.1016/ 0301-0082(92)90005-Y 1529103
    • (1992) Prog Neurobiol , vol.39 , pp. 517-545
    • Francis, P.T.1    Pangalos, M.N.2    Bowen, D.M.3
  • 4
    • 0033625087 scopus 로고    scopus 로고
    • The 5-HT1A antagonist, WAY 100 635, alleviates cognitive impairments induced by dizocilpine (MK-801) in monkeys
    • 10.1016/S0028-3908(99)00179-3 10728875
    • Harder JA Ridley RM The 5-HT1A antagonist, WAY 100 635, alleviates cognitive impairments induced by dizocilpine (MK-801) in monkeys Neuropharmacology 2000, 39:547-52 10.1016/S0028-3908(99)00179-3 10728875
    • (2000) Neuropharmacology , vol.39 , pp. 547-552
    • Harder, J.A.1    Ridley, R.M.2
  • 5
    • 1642331289 scopus 로고    scopus 로고
    • Serotonin-induced increases in adult cell proliferation and neurogenesis are mediated through different and common 5-HT receptor subtypes in the dentate gyrus and the subventricular zone
    • 10.1038/sj.npp.1300320 14872203
    • Banasr M Hery M Printemps R Daszuta A Serotonin-induced increases in adult cell proliferation and neurogenesis are mediated through different and common 5-HT receptor subtypes in the dentate gyrus and the subventricular zone Neuropsychopharmacology 2004, 29:450-60 10.1038/ sj.npp.1300320 14872203
    • (2004) Neuropsychopharmacology , vol.29 , pp. 450-460
    • Banasr, M.1    Hery, M.2    Printemps, R.3    Daszuta, A.4
  • 6
    • 33845613251 scopus 로고    scopus 로고
    • Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans
    • 10.1523/JNEUROSCI.3448-06.2006 17167099
    • Wu Y Wu Z Butko P Christen Y Lambert MP Klein WL Link CD Luo Y Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans J Neurosci 2006, 26:13102-13 10.1523/JNEUROSCI.3448-06.2006 17167099
    • (2006) J Neurosci , vol.26 , pp. 13102-13113
    • Wu, Y.1    Wu, Z.2    Butko, P.3    Christen, Y.4    Lambert, M.P.5    Klein, W.L.6    Link, C.D.7    Luo, Y.8
  • 7
    • 0033394501 scopus 로고    scopus 로고
    • Bilobalide, a constituent of Ginkgo biloba, inhibits NMDA-induced phospholipase A2 activation and phospholipid breakdown in rat hippocampus
    • 10.1007/s002109900131 10619176
    • Weichel O Hilgert M Chatterjee SS Lehr M Klein J Bilobalide, a constituent of Ginkgo biloba, inhibits NMDA-induced phospholipase A2 activation and phospholipid breakdown in rat hippocampus Naunyn Schmiedebergs Arch Pharmacol 1999, 360:609-15 10.1007/s002109900131 10619176
    • (1999) Naunyn Schmiedebergs Arch Pharmacol , vol.360 , pp. 609-615
    • Weichel, O.1    Hilgert, M.2    Chatterjee, S.S.3    Lehr, M.4    Klein, J.5
  • 8
    • 0035924368 scopus 로고    scopus 로고
    • Neuroprotective effects of bilobalide, a component of the Ginkgo biloba extract (EGb 761), in gerbil global brain ischemia
    • 10.1016/S0006-8993(01)03188-2 11743961
    • Chandrasekaran K Mehrabian Z Spinnewyn B Drieu K Fiskum G Neuroprotective effects of bilobalide, a component of the Ginkgo biloba extract (EGb 761), in gerbil global brain ischemia Brain Res 2001, 922:282-92 10.1016/S0006-8993(01)03188-2 11743961
    • (2001) Brain Res , vol.922 , pp. 282-292
    • Chandrasekaran, K.1    Mehrabian, Z.2    Spinnewyn, B.3    Drieu, K.4    Fiskum, G.5
  • 9
    • 0030907753 scopus 로고    scopus 로고
    • Phospholipid breakdown and choline release under hypoxic conditions: Inhibition by bilobalide, a constituent of Ginkgo biloba
    • 10.1016/S0006-8993(97)00239-4 9175905
    • Klein J Chatterjee SS Loffelholz K Phospholipid breakdown and choline release under hypoxic conditions: Inhibition by bilobalide, a constituent of Ginkgo biloba Brain Res 1997, 755:347-50 10.1016/ S0006-8993(97)00239-4 9175905
    • (1997) Brain Res , vol.755 , pp. 347-350
    • Klein, J.1    Chatterjee, S.S.2    Loffelholz, K.3
  • 10
    • 33846027443 scopus 로고    scopus 로고
    • Role of GABAergic antagonism in the neuroprotective effects of bilobalide
    • 1865101 17134681 10.1016/j.brainres.2006.10.042
    • Kiewert C Kumar V Hildmann O Rueda M Hartmann J Naik RS Klein J Role of GABAergic antagonism in the neuroprotective effects of bilobalide Brain Res 2007, 1128:70-8 1865101 17134681 10.1016/j.brainres.2006.10.042
    • (2007) Brain Res , vol.1128 , pp. 70-78
    • Kiewert, C.1    Kumar, V.2    Hildmann, O.3    Rueda, M.4    Hartmann, J.5    Naik, R.S.6    Klein, J.7
  • 11
    • 0036278294 scopus 로고    scopus 로고
    • Effects of bilobalide on amino acid release and electrophysiology of cortical slices
    • 10.1007/s007260200021 12107763
    • Jones FA Chatterjee SS Davies JA Effects of bilobalide on amino acid release and electrophysiology of cortical slices Amino Acids 2002, 22:369-79 10.1007/s007260200021 12107763
    • (2002) Amino Acids , vol.22 , pp. 369-379
    • Jones, F.A.1    Chatterjee, S.S.2    Davies, J.A.3
  • 12
    • 0033714116 scopus 로고    scopus 로고
    • C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway
    • 10.1016/S0896-6273(00)81199-X 10896158
    • Sawin ER Ranganathan R Horvitz HR C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway Neuron 2000, 26:619-31 10.1016/ S0896-6273(00)81199-X 10896158
    • (2000) Neuron , vol.26 , pp. 619-631
    • Sawin, E.R.1    Ranganathan, R.2    Horvitz, H.R.3
  • 13
    • 43849106772 scopus 로고    scopus 로고
    • Manipulation of serotonin signal suppresses early phase of behavioral aging in Caenorhabditis elegans
    • 10.1016/j.neurobiolaging.2007.01.013 17336425
    • Murakami H Bessinger K Hellmann J Murakami S Manipulation of serotonin signal suppresses early phase of behavioral aging in Caenorhabditis elegans Neurobiol Aging 2007, 29(7):1093-100 10.1016/ j.neurobiolaging.2007.01.013 17336425
    • (2007) Neurobiol Aging , vol.29 , Issue.7 , pp. 1093-1100
    • Murakami, H.1    Bessinger, K.2    Hellmann, J.3    Murakami, S.4
  • 14
    • 0034707063 scopus 로고    scopus 로고
    • MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
    • 10.1038/35044083 11100728
    • Ranganathan R Cannon SC Horvitz HR MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans Nature 2000, 408:470-5 10.1038/35044083 11100728
    • (2000) Nature , vol.408 , pp. 470-475
    • Ranganathan, R.1    Cannon, S.C.2    Horvitz, H.R.3
  • 15
    • 0031068606 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of a serotonin receptor from Caenorhabditis elegans
    • 10.1007/BF02736863 9061615
    • Olde B McCombie WR Molecular cloning and functional expression of a serotonin receptor from Caenorhabditis elegans J Mol Neurosci 1997, 8:53-62 10.1007/BF02736863 9061615
    • (1997) J Mol Neurosci , vol.8 , pp. 53-62
    • Olde, B.1    McCombie, W.R.2
  • 16
    • 0033037612 scopus 로고    scopus 로고
    • Characterization of a novel serotonin receptor from Caenorhabditis elegans: Cloning and expression of two splice variants
    • 10.1046/j.1471-4159.1999.721372.x 10098838
    • Hamdan FF Ungrin MD Abramovitz M Ribeiro P Characterization of a novel serotonin receptor from Caenorhabditis elegans: Cloning and expression of two splice variants J Neurochem 1999, 72:1372-83 10.1046/ j.1471-4159.1999.721372.x 10098838
    • (1999) J Neurochem , vol.72 , pp. 1372-1383
    • Hamdan, F.F.1    Ungrin, M.D.2    Abramovitz, M.3    Ribeiro, P.4
  • 17
    • 0141643100 scopus 로고    scopus 로고
    • SER-7b, a constitutively active Galphas coupled 5-HT7-like receptor expressed in the Caenorhabditis elegans M4 pharyngeal motorneuron
    • 10.1046/j.1471-4159.2003.01967.x 12969249
    • Hobson RJ Geng J Gray AD Komuniecki RW SER-7b, a constitutively active Galphas coupled 5-HT7-like receptor expressed in the Caenorhabditis elegans M4 pharyngeal motorneuron J Neurochem 2003, 87:22-9 10.1046/ j.1471-4159.2003.01967.x 12969249
    • (2003) J Neurochem , vol.87 , pp. 22-29
    • Hobson, R.J.1    Geng, J.2    Gray, A.D.3    Komuniecki, R.W.4
  • 18
    • 0028835184 scopus 로고
    • Genetic and pharmacological analysis of neurotransmitters controlling egg laying in C. elegans
    • 7472454
    • Weinshenker D Garriga G Thomas JH Genetic and pharmacological analysis of neurotransmitters controlling egg laying in C. elegans J Neurosci 1995, 15:6975-85 7472454
    • (1995) J Neurosci , vol.15 , pp. 6975-6985
    • Weinshenker, D.1    Garriga, G.2    Thomas, J.H.3
  • 19
    • 17444408824 scopus 로고    scopus 로고
    • Serotonin (5HT), fluoxetine, imipramine and dopamine target distinct 5HT receptor signaling to modulate Caenorhabditis elegans egg-laying behavior
    • 1449529 15654117 10.1534/genetics.104.032540
    • Dempsey CM Mackenzie SM Gargus A Blanco G Sze JY Serotonin (5HT), fluoxetine, imipramine and dopamine target distinct 5HT receptor signaling to modulate Caenorhabditis elegans egg-laying behavior Genetics 2005, 169:1425-36 1449529 15654117 10.1534/genetics.104.032540
    • (2005) Genetics , vol.169 , pp. 1425-1436
    • Dempsey, C.M.1    Mackenzie, S.M.2    Gargus, A.3    Blanco, G.4    Sze, J.Y.5
  • 20
    • 0342680006 scopus 로고    scopus 로고
    • Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant
    • 10.1038/35000609 10676966
    • Sze JY Victor M Loer C Shi Y Ruvkun G Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant Nature 2000, 403:560-4 10.1038/35000609 10676966
    • (2000) Nature , vol.403 , pp. 560-564
    • Sze, J.Y.1    Victor, M.2    Loer, C.3    Shi, Y.4    Ruvkun, G.5
  • 21
    • 0035882491 scopus 로고    scopus 로고
    • Mutations in the Caenorhabditis elegans serotonin reuptake transporter MOD-5 reveal serotonin-dependent and -independent activities of fluoxetine
    • 11487610
    • Ranganathan R Sawin ER Trent C Horvitz HR Mutations in the Caenorhabditis elegans serotonin reuptake transporter MOD-5 reveal serotonin-dependent and -independent activities of fluoxetine J Neurosci 2001, 21:5871-84 11487610
    • (2001) J Neurosci , vol.21 , pp. 5871-5884
    • Ranganathan, R.1    Sawin, E.R.2    Trent, C.3    Horvitz, H.R.4
  • 22
    • 0033198830 scopus 로고    scopus 로고
    • Serotonin inhibition of synaptic transmission: Galpha(0) decreases the abundance of UNC-13 at release sites
    • 10.1016/S0896-6273(00)80835-1 10677040
    • Nurrish S Segalat L Kaplan JM Serotonin inhibition of synaptic transmission: Galpha(0) decreases the abundance of UNC-13 at release sites Neuron 1999, 24:231-42 10.1016/S0896-6273(00)80835-1 10677040
    • (1999) Neuron , vol.24 , pp. 231-242
    • Nurrish, S.1    Segalat, L.2    Kaplan, J.M.3
  • 23
    • 34447632659 scopus 로고    scopus 로고
    • Serotonin receptors antagonistically modulate Caenorhabditis elegans longevity
    • 10.1111/j.1474-9726.2007.00303.x 17559503
    • Murakami H Murakami S Serotonin receptors antagonistically modulate Caenorhabditis elegans longevity Aging Cell 2007, 6:483-8 10.1111/ j.1474-9726.2007.00303.x 17559503
    • (2007) Aging Cell , vol.6 , pp. 483-488
    • Murakami, H.1    Murakami, S.2
  • 25
    • 36549006956 scopus 로고    scopus 로고
    • An antidepressant that extends lifespan in adult Caenorhabditis elegans
    • 10.1038/nature05991 18033297
    • Petrascheck M Ye X Buck LB An antidepressant that extends lifespan in adult Caenorhabditis elegans Nature 2007, 450:553-6 10.1038/nature05991 18033297
    • (2007) Nature , vol.450 , pp. 553-556
    • Petrascheck, M.1    Ye, X.2    Buck, L.B.3
  • 27
    • 0020808726 scopus 로고
    • Egg-laying defective mutants of the nematode Caenorhabditis elegans
    • 1202130 11813735
    • Trent C Tsuing N Horvitz HR Egg-laying defective mutants of the nematode Caenorhabditis elegans Genetics 1983, 104:619-47 1202130 11813735
    • (1983) Genetics , vol.104 , pp. 619-647
    • Trent, C.1    Tsuing, N.2    Horvitz, H.R.3
  • 28
    • 1542677090 scopus 로고    scopus 로고
    • Terpene trilactones from Ginkgo biloba are antagonists of cortical glycine and GABA(A) receptors
    • 10.1074/jbc.M304034200 14504293
    • Ivic L Sands TT Fishkin N Nakanishi K Kriegstein AR Stromgaard K Terpene trilactones from Ginkgo biloba are antagonists of cortical glycine and GABA(A) receptors J Biol Chem 2003, 278:49279-85 10.1074/jbc.M304034200 14504293
    • (2003) J Biol Chem , vol.278 , pp. 49279-49285
    • Ivic, L.1    Sands, T.T.2    Fishkin, N.3    Nakanishi, K.4    Kriegstein, A.R.5    Stromgaard, K.6
  • 29
    • 0029670697 scopus 로고    scopus 로고
    • A critical role for D1 receptors in the 5-HT1A-mediated facilitation of in vivo acetylcholine release in rat frontal cortex
    • 10.1016/0006-8993(95)01369-5 8919313
    • Consolo S Ramponi S Ladinsky H Baldi G A critical role for D1 receptors in the 5-HT1A-mediated facilitation of in vivo acetylcholine release in rat frontal cortex Brain Res 1996, 707:320-3 10.1016/ 0006-8993(95)01369-5 8919313
    • (1996) Brain Res , vol.707 , pp. 320-323
    • Consolo, S.1    Ramponi, S.2    Ladinsky, H.3    Baldi, G.4
  • 30
    • 7444250275 scopus 로고    scopus 로고
    • Age-dependent effects of serotonin-1A receptor gene deletion in spatial learning abilities in mice
    • 10.1016/j.molbrainres.2004.07.012 15519675
    • Wolff M Costet P Gross C Hen R Segu L Buhot MC Age-dependent effects of serotonin-1A receptor gene deletion in spatial learning abilities in mice Brain Res Mol Brain Res 2004, 130:39-48 10.1016/ j.molbrainres.2004.07.012 15519675
    • (2004) Brain Res Mol Brain Res , vol.130 , pp. 39-48
    • Wolff, M.1    Costet, P.2    Gross, C.3    Hen, R.4    Segu, L.5    Buhot, M.C.6
  • 31
    • 0032758813 scopus 로고    scopus 로고
    • S 15535, a benzodioxopiperazine acting as presynaptic agonist and postsynaptic 5-HT1A receptor antagonist, prevents the impairment of spatial learning caused by intrahippocampal scopolamine
    • 1571756 10578133 10.1038/sj.bjp.0702915
    • Carli M Balducci C Millan MJ Bonalumi P Samanin R S 15535, a benzodioxopiperazine acting as presynaptic agonist and postsynaptic 5-HT1A receptor antagonist, prevents the impairment of spatial learning caused by intrahippocampal scopolamine Br J Pharmacol 1999, 128:1207-14 1571756 10578133 10.1038/sj.bjp.0702915
    • (1999) Br J Pharmacol , vol.128 , pp. 1207-1214
    • Carli, M.1    Balducci, C.2    Millan, M.J.3    Bonalumi, P.4    Samanin, R.5
  • 33
    • 43849106772 scopus 로고    scopus 로고
    • Manipulation of serotonin signal suppresses early phase of behavioral aging in Caenorhabditis elegans
    • 10.1016/j.neurobiolaging.2007.01.013 17336425
    • Murakami H Bessinger K Hellmann J Murakami S Manipulation of serotonin signal suppresses early phase of behavioral aging in Caenorhabditis elegans Neurobiol Aging 2008, 29:1093-100 10.1016/ j.neurobiolaging.2007.01.013 17336425
    • (2008) Neurobiol Aging , vol.29 , pp. 1093-1100
    • Murakami, H.1    Bessinger, K.2    Hellmann, J.3    Murakami, S.4
  • 34
    • 0037310558 scopus 로고    scopus 로고
    • Selective 5-HT1A antagonists WAY 100635 and NAD-299 attenuate the impairment of passive avoidance caused by scopolamine in the rat
    • 10.1038/sj.npp.1300024 12589378
    • Misane I Ogren SO Selective 5-HT1A antagonists WAY 100635 and NAD-299 attenuate the impairment of passive avoidance caused by scopolamine in the rat Neuropsychopharmacology 2003, 28:253-64 10.1038/sj.npp.1300024 12589378
    • (2003) Neuropsychopharmacology , vol.28 , pp. 253-264
    • Misane, I.1    Ogren, S.O.2
  • 35
    • 0019977293 scopus 로고
    • Serotonin and octopamine in the nematode Caenorhabditis elegans
    • 10.1126/science.6805073 6805073
    • Horvitz HR Chalfie M Trent C Sulston JE Evans PD Serotonin and octopamine in the nematode Caenorhabditis elegans Science 1982, 216:1012-4 10.1126/science.6805073 6805073
    • (1982) Science , vol.216 , pp. 1012-1014
    • Horvitz, H.R.1    Chalfie, M.2    Trent, C.3    Sulston, J.E.4    Evans, P.D.5
  • 36
    • 0032125818 scopus 로고    scopus 로고
    • Control of alternative behavioral states by serotonin in Caenorhabditis elegans
    • 10.1016/S0896-6273(00)80527-9 9697864
    • Waggoner LE Zhou GT Schafer RW Schafer WR Control of alternative behavioral states by serotonin in Caenorhabditis elegans Neuron 1998, 21:203-14 10.1016/S0896-6273(00)80527-9 9697864
    • (1998) Neuron , vol.21 , pp. 203-214
    • Waggoner, L.E.1    Zhou, G.T.2    Schafer, R.W.3    Schafer, W.R.4
  • 37
    • 27944439593 scopus 로고    scopus 로고
    • The G-protein-coupled serotonin receptor SER-1 regulates egg laying and male mating behaviors in Caenorhabditis elegans
    • 10.1523/JNEUROSCI.3399-05.2005 16291940
    • Carnell L Illi J Hong SW McIntire SL The G-protein-coupled serotonin receptor SER-1 regulates egg laying and male mating behaviors in Caenorhabditis elegans J Neurosci 2005, 25:10671-81 10.1523/ JNEUROSCI.3399-05.2005 16291940
    • (2005) J Neurosci , vol.25 , pp. 10671-10681
    • Carnell, L.1    Illi, J.2    Hong, S.W.3    McIntire, S.L.4
  • 38
    • 59649086786 scopus 로고    scopus 로고
    • Dual excitatory and inhibitory serotonergic inputs modulate egg laying in Caenorhabditis elegans
    • 2621164 19001289 10.1534/genetics.108.096891
    • Hapiak VM Hobson RJ Hughes L Smith K Harris G Condon C Komuniecki P Komuniecki RW Dual excitatory and inhibitory serotonergic inputs modulate egg laying in Caenorhabditis elegans Genetics 2009, 181:153-63 2621164 19001289 10.1534/genetics.108.096891
    • (2009) Genetics , vol.181 , pp. 153-163
    • Hapiak, V.M.1    Hobson, R.J.2    Hughes, L.3    Smith, K.4    Harris, G.5    Condon, C.6    Komuniecki, P.7    Komuniecki, R.W.8
  • 41
    • 0028981288 scopus 로고
    • Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans
    • 40986 7568134 10.1073/pnas.92.20.9368
    • Link CD Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans Proc Natl Acad Sci USA 1995, 92:9368-72 40986 7568134 10.1073/pnas.92.20.9368
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9368-9372
    • Link, C.D.1
  • 42
    • 33846206505 scopus 로고    scopus 로고
    • Beneficial effects of natural antioxidants EGCG and alpha-lipoic acid on life span and age-dependent behavioral declines in Caenorhabditis elegans
    • 10.1016/j.pbb.2006.10.017 17156833
    • Brown MK Evans JL Luo Y Beneficial effects of natural antioxidants EGCG and alpha-lipoic acid on life span and age-dependent behavioral declines in Caenorhabditis elegans Pharmacol Biochem Behav 2006, 85:620-8 10.1016/ j.pbb.2006.10.017 17156833
    • (2006) Pharmacol Biochem Behav , vol.85 , pp. 620-628
    • Brown, M.K.1    Evans, J.L.2    Luo, Y.3


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