Prolonged treatment with valganciclovir in an infant with congenital cytomegalovirus infection;Tratamiento prolongado con valganciclovir en un lactante con infección congénita por citomegalovirus

Anales de Pediatria

Volumn 70, Issue 6, 2009, Pages 578-581

  Baquero Artigao, F ^a   Romero Gomez M P ^b  

^a HOSPITAL INFANTIL LA PAZ   (Spain)

^b HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

Author keywords

Congenital cytomegalovirus; Ganciclovir; Hearing loss; Symptomatic infection; Valganciclovir

Indexed keywords

GANCICLOVIR; VALGANCICLOVIR;

ARTICLE; CASE REPORT; CENTRAL NERVOUS SYSTEM INFECTION; CHILD; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; ELECTROENCEPHALOGRAM; FEMALE; HEARING IMPAIRMENT; HUMAN; INFANT; LONG TERM CARE; NEWBORN INFECTION; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL EXAMINATION; POLYMERASE CHAIN REACTION; TREATMENT DURATION; VIRUS LOAD;

ANTIVIRAL AGENTS; CYTOMEGALOVIRUS INFECTIONS; FEMALE; GANCICLOVIR; HUMANS; INFANT, NEWBORN; TIME FACTORS;

EID: 67849128565     PISSN: 16954033     EISSN: 16959531     Source Type: Journal    
DOI: 10.1016/j.anpedi.2009.01.010     Document Type: Article

References (16)

1. S.C. Dollard, S.D. Grosse, and D.S. Ross New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection Rev Med Virol 17 2007 353 363
2. Stagno S, Britt B. Cytomegalovirus. In: Remington JS, Klein JO, Wilson CB, Baker CJ, editores. Infectious diseases of the fetus and newborn infant. 6th ed. Philadelphia: Elsevier Saunders; 2006. p. 740-81.
3. K.B. Fowler, A.J. Dahle, S.B. Boppana, and R.F. Pass Newborn hearing screening: Will children with hearing loss caused by congenital cytomegalovirus infection be missed? J Pediatr 135 1999 60 64
4. D.W. Kimberlin, C.Y. Lin, P.J. Sánchez, G.J. Demmler, W. Dankner, and M. Shelton Effect of ganciclovir therapy on hearing in symptomatic congenital cytomegalovirus disease involving the central nervous system: A randomized, controlled trial J Pediatr 143 2003 16 25
5. E.P. Acosta, R.C. Brundage, J.R. King, P.J. Sánchez, S. Sood, and V. Agrawal Ganciclovir population pharmacokinetics in neonates following intravenous administration of ganciclovir and oral administration of a liquid valganciclovir formulation Clin Pharmacol Ther 81 2007 867 872
6. R.J. Whitley, G. Cloud, W. Gruber, G.A. Storch, G.J. Demmler, and R.F. Jacobs Ganciclovir treatment of symptomatic congenital cytomegalovirus infection: Results of a phase ii study. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group J Infect Dis 175 1997 1080 1086
7. D.E. Noyola, J. Demmler G, C.T. Nelson, C. Griesser, W.D. Williamson, and J.T. Atkins Early predictors of neurodevelopmental outcome in symptomatic congenital cytomegalovirus infection J Pediatr 138 2001 325 331
8. S.P. Adler, G. Nigro, and L. Pereira Recent advances in the prevention and treatment of congenital cytomegalovirus infections Semin Perinatol 31 2007 10 18
9. M.G. Michaels, D.P. Greenberg, D.L. Sabo, and E.R. Wald Treatment of children with congenital cytomegalovirus infection with ganciclovir Pediatr Infect Dis J 22 2003 504 509
10. P. Rojo, and J.T. Ramos Ganciclovir treatment of children with congenital cytomegalovirus infection Pediatr Infect Dis J 23 2004 88 89
11. ®. Ficha técnica o resumen de las características del producto. Disponible en: http://www.roche- trasplantes.com/web/pdf/fitxa-valcyte08.pdf.
12. L. Galli, A. Novelli, E. Chiappini, P. Gervaso, M.I. Casseta, and S. Fallani Valganciclovir for congenital CMV infection: A pilot study on plasma concentration in newborns and infants Pediatr Infect Dis J 26 2007 451 453
13. D.W. Kimberlin, E.P. Acosta, P.J. Sánchez, S. Sood, V. Agrawal, and J. Homans Pharmacokinetic and pharmacodynamic assesment of oral valganciclovir in the treatment of symptomatic congenital cytomegalovirus disease J Infect Dis 197 2008 836 845
14. C.F. Meine Jansen, M.C. Toet, C.M. Rademaker, T.F. Ververs, L.J. Gerards, and A.M. Van Loon Treatment of symptomatic congenital cytomegalovirus infection with valganciclovir J Perinat Med 33 2005 364 366
15. S. Schulzke, and C. Buhrer Valganciclovir for treatment of congenital cytomegalovirus infection Eur J Pediatr 165 2006 575 576
16. A. Müller, A.M. Eis-Hübinger, G. Brandhorst, A. Heep, P. Bartmann, and A.R. Franz Oral valganciclovir for symptomatic congenital cytomegalovirus infection in an extremely low birth weight infant J Perinatol 28 2008 74 76