Insertion/deletion polymorphism of the bradykinin type 2 receptor gene influence diastolic blood pressure

Journal of Human Hypertension

Volumn 23, Issue 8, 2009, Pages 553-555

  Freitas, S R ^a,b   Pereira, A C ^a   Floriano, M S ^a   Mill, J G ^c   Krieger, J E ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c FEDERAL UNIVERSITY OF ESPÍRITO SANTO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ B2 RECEPTOR; GENOMIC DNA;

ADULT; AGE; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; DIASTOLIC BLOOD PRESSURE; ETHNICITY; FEMALE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; OBESITY; PHENOTYPE; SEX DIFFERENCE;

ADULT; BLOOD PRESSURE; BRAZIL; CROSS-SECTIONAL STUDIES; DIASTOLE; FEMALE; HUMANS; HYPERTENSION; INDEL MUTATION; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PREDICTIVE VALUE OF TESTS; RECEPTOR, BRADYKININ B2; RISK FACTORS; URBAN POPULATION;

EID: 67849122298     PISSN: 09509240     EISSN: 14765527     Source Type: Journal    
DOI: 10.1038/jhh.2009.23     Document Type: Article

References (12)

1. Sharma JN. Does the Kinin System Mediate in Cardiovascular Abnormalities? An Overview. J Clin Pharmacol 2003; 43: 1187-1195.
2. Dhamrait SS, Payne JR, Li P, Jones A, Toor IS, Cooper JA et al. Variation in bradykinin receptor genes increases the cardiovascular risk associated with hypertension. Eur Heart J 2003; 24: 1672-1680.
3. Hallberg P, Lind L, Michaelsson K, Karlsson J, Kurland L, Kahan T et al. B2 bradykinin receptor (B2BKR) polymorphism and change in left ventricular mass in response to antihypertensive treatment: Results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial. J Hypertens 2003; 21: 621-624.
4. Braun A, Kemmerer S, Böhme E, Muller B, Roscher AA. Identification of polymorphic sites of the human bradykinin B2 receptor site. Biochem Biophys Res Commun 1995; 211(1): 234-240.
5. Braun A, Kemmerer S, Maier E, Böhme E, Roscher AA. Polymorphisms in the gene for the human B2-bradykinin receptor. New tools in assessing a genetic risk for bradykinin-associated diseases. Immunopharmacology 1996; 33: 32-35.
6. Lung CC, Chan EK, Zuraw BL. Analysis of an exon 1 polymorphism of the B2 bradykinin receptor gene and its transcript in normal subjects and patients with C1 inhibitor deficiency. J Allergy Clin Immunol 1997; 99: 134-146.
7. The World Health Organization MONICA Project (monitoring trends and determinants in cardiovascular disease): A major international collaboration. WHO MONICA Project Principal Investigators. J Clin Epidemiol 1988; 41: 105-114.
8. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988; 16: 1215.
9. Kemmerer S, Braun A, Arnold N, Roscher AA. The human bradykinin 2 receptor gene: Full length cDNA, genomic organization and identification of the regulatory region. Biochem Biophys Res Commun 1995; 221 226-233.
10. Pretorious MM, Gainer JV, Van Guilder GP, Coelho EB, Luther JM, Fong P, Rosenbaum DD et al. The bradykinin type 2 receptor BE1 polymorphism and ethnicity influence systolic blood pressure and vascular resistance. Clin Pharmacol Ther 2008; 83(1): 122-129.
11. Cui J, Melista E, Chazaro I, Zhang Y, Zhou X, Manolis AJ, Baldwin CT et al. Sequence variation of bradykinin receptors B1 and B2 and association with hypertension. J Hypertens 2005; 23: 55-62.
12. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo Jr JL et al. National Heart LaBIJNCoPDEaToHBP, National High Blood Pressure Education Program Coordinating C. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: The JNC 7 report. (see comment (erratum appears in JAMA, 2003 July 9; 290(2):197). JAMA 2003; 289 2560-2572.