High aldolase with normal creatine kinase in serum predicts a myopathy with perimysial pathology

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 80, Issue 8, 2009, Pages 904-908

  Nozaki, K ^a   Pestronk, A ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID PHOSPHATASE; ANTINUCLEAR ANTIBODY; AZATHIOPRINE; CREATINE KINASE; FRUCTOSE BISPHOSPHATE ALDOLASE; JO 1 ANTIBODY; METHYLPREDNISOLONE; MYCOPHENOLIC ACID; PREDNISONE; TACROLIMUS; BIOLOGICAL MARKER;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADOLESCENT; ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY TITER; ARTHRALGIA; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL EVALUATION; CLINICAL FEATURE; CONNECTIVE TISSUE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DISEASE ASSOCIATION; DISEASE EXACERBATION; ELECTROMYOGRAPHY; ENZYME BLOOD LEVEL; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LOW DRUG DOSE; LUNG DISEASE; MALE; MEDICAL RECORD REVIEW; MUSCLE BIOPSY; MUSCLE WEAKNESS; MYOPATHY; MYOSITIS; NEUROMUSCULAR DISEASE; PERIMYSIUM; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; SKIN DISEASE; BIOPSY; BLOOD; ENZYMOLOGY; MIDDLE AGED; PATHOLOGY; SKELETAL MUSCLE;

ADOLESCENT; ADULT; BIOLOGICAL MARKERS; BIOPSY; CHILD, PRESCHOOL; CREATINE KINASE; ELECTROMYOGRAPHY; FEMALE; FRUCTOSE-BISPHOSPHATE ALDOLASE; HUMANS; MALE; MIDDLE AGED; MUSCLE, SKELETAL; NEUROMUSCULAR DISEASES;

EID: 67849116994     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp.2008.161448     Document Type: Article

References (15)

1. Lott JA, Landesman PW. The enzymology of skeletal muscle disorders. Crit Rev Clin Lab Sci 1984;20:153-90.
2. Engel AG, Franzini-Armstrong C. Myology: basic and clinical. New York: McGraw-Hill, 2004.
3. Fujimoto M, Sato S, Ihn H, et al. Serum aldolase level is a useful indicator of disease activity in eosinophilic fasciitis. J Rheumatol 1995;22:563-5.
4. Quintero-Del-Rio AI, Punaro M, Pascual V. Faces of eosinophilic fasciitis in childhood. J Clin Rheumatol 2002;8:99-103.
5. Carter JD, Kanik KS, Vasey FB, et al. Dermatomyositis with normal creatine kinase and elevated aldolase levels. J Rheumatol 2001;28:2366-7.
6. Sato S, Hirakata M, Kuwana M, et al. Autoantibodies to a 140-kd polypeptide, CADM-140, in Japanese patients with clinically amyopathic dermatomyositis. Arthritis Rheum 2005;52:1571-6
7. Miller T, Al Lozi MT, Lopate G, et al. Myopathy with antibodies to the signal recognition particle: clinical and pathological features. J Neurol Neurosurg Psychiatry 2002;73:420-8.
8. Mozaffar T, Pestronk A. Myopathy with anti-Jo-1 antibodies: pathology in perimysium and neighbouring muscle fibres. J Neurol Neurosurg Psychiatry 2000;68:472-8.
9. Schmidt WA, Wetzel W, Friedlander R, et al. Clinical and serological aspects of patients with anti-Jo-1 antibodies: an evolving spectrum of disease manifestations. Clin Rheumatol 2000;19:371-7.
10. Zivkovic SA, Lacomis D, Clemens PR. Chronic eosinophilic perimyositis with persistent myalgias. Muscle Nerve 2002;25:461-5.
11. Emslie-Smith AM, Engel AG. Microvascular changes in early and advanced dermatomyositis: a quantitative study. Ann Neurol 1990;27:343-56.
12. Kissel JT, Mendell JR, Rammohan KW. Microvascular deposition of complement membrane attack complex in dermatomyositis. N Engl J Med 1986;314:329-34.
13. Pestronk A. Creatine kinase. Neuromuscular Disease Center 2009 World Wide Web URL: http://neuromuscular.wustl.edu/lab/cknomyo.html#cklow (accessed 6 May 2009).
14. Rosalki SB. Low serum creatine kinase activity. Clin Chem 1998;44:905.
15. Lacomis D. The utility of muscle biopsy. Curr Neurol Neurosci Rep 2004;4:81-6.