Growth kinetics and transplantation of human retinal progenitor cells

Experimental Eye Research

Volumn 89, Issue 3, 2009, Pages 301-310

  Aftab, Unber ^a   Jiang, Caihui ^a   Tucker, Budd ^a   Kim, Ji Yeon ^a   Klassen, Henry ^b   Miljan, Erik ^c   Sinden, John ^c   Young, Michael ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c RENEURON LTD   (United Kingdom)

Author keywords

cell culture; growth kinetics; human retinal progenitor cells; population doubling level; transplantation

Indexed keywords

BIOLOGICAL MARKER; KI 67 ANTIGEN; NESTIN; RHODOPSIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR LHX2; TRANSCRIPTION FACTOR PAX6; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CELL EXPANSION; CELL GROWTH; CELL ISOLATION; CELL LINEAGE; CELL MATURATION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DONOR; EXPLANT; GESTATIONAL AGE; GROWTH RATE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOCYTOCHEMISTRY; LASER COAGULATION; MOUSE; NEWBORN; NONHUMAN; PHOTORECEPTOR; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA DEGENERATION; RETINA STEM CELL TRANSPLANTATION; STEM CELL TRANSPLANTATION;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; FETAL STEM CELLS; FETAL TISSUE TRANSPLANTATION; GESTATIONAL AGE; HUMANS; MICE; MICE, KNOCKOUT; PHOTORECEPTOR CELLS, VERTEBRATE; POLYMERASE CHAIN REACTION; RETINA; RHODOPSIN; STEM CELL TRANSPLANTATION;

EID: 67849115972     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2009.03.025     Document Type: Article

References (23)

1. Banin E., Obolensky A., Idelson M., Hemo I., Reinhardtz E., Pikarsky E., Ben-Hur T., and Reubinoff B. Retinal incorporation and differentiation of neural precursors derived from human embryonic stem cells. Stem Cells 24 (2006) 246-257
2. Bibb L.C., Holt J.K., Tarttelin E.E., Hodges M.D., Gregory-Evans K., Rutherford A., Lucas R.J., Sowden J.C., and Gregory-Evans C.Y. Temporal and spatial expression patterns of the CRX transcription factor and its downstream targets. Critical differences during human and mouse eye development. Hum. Mol. Genet. 10 (2001) 1571-1579
3. Carter D.A., Mayer E.J., and Dick A.D. The effect of postmortem time, donor age and sex on the generation of neurospheres from adult human retina. Br. J. Ophthalmol. 91 (2007) 1216-1218
4. Cepko C.L., Austin C.P., Yang X., Alexiades M., and Ezzeddine D. Cell fate determination in the vertebrate retina. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 589-595
5. Chacko D.M., Rogers J.A., Turner J.E., and Ahmad I. Survival and differentiation of cultured retinal progenitors transplanted in the subretinal space of the rat. Biochem. Biophys. Res. Commun. 268 (2000) 842-846
6. Chow A.Y., Chow V.Y., Packo K.H., Pollack J.S., Peyman G.A., and Schuchard R. The artificial silicon retina microchip for the treatment of vision loss from retinitis pigmentosa. Arch. Ophthalmol. 122 (2004) 460-469
7. Colodetti L., Weiland J.D., Colodetti S., Ray A., Seiler M.J., Hinton D.R., and Humayun M.S. Pathology of damaging electrical stimulation in the retina. Exp. Eye Res. 85 (2007) 23-33
8. Cosset F.L., Takeuchi Y., Battini J.L., Weiss R.A., and Collins M.K. High-titer packaging cells producing recombinant retroviruses resistant to human serum. J. Virol. 69 (1995) 7430-7436
9. Kelley M.W., Turner J.K., and Reh T.A. Regulation of proliferation and photoreceptor differentiation in fetal human retinal cell cultures. Invest. Ophthalmol. Vis. Sci. 36 (1995) 1280-1289
10. Klassen H.J., Ng T.F., Kurimoto Y., Kirov I., Shatos M., Coffey P., and Young M.J. Multipotent retinal progenitors express developmental markers, differentiate into retinal neurons, and preserve light-mediated behavior. Invest. Ophthalmol. Vis. Sci. 45 (2004) 4167-4173
11. Klassen H., Ziaeian B., Kirov II, Young M.J., and Schwartz P.H. Isolation of retinal progenitor cells from post-mortem human tissue and comparison with autologous brain progenitors. J. Neurosci. Res. 77 (2004) 334-343
12. Klassen H., Kiilgaard J.F., Zahir T., Ziaeian B., Kirov I., Scherfig E., Warfvinge K., and Young M. Progenitor cells from the porcine neural retina express photoreceptor markers after transplantation to the subretinal space of allorecipients. Stem Cells 25 (2007) 1222-1230
13. Kolb H., Zhang L., and Dekorver L. Differential staining of neurons in the human retina with antibodies to protein kinase C isozymes. Vis. Neurosci. 10 (1993) 341-351
14. Kucia M., Reca R., Campbell F.R., Zuba-Surma E., Majka M., Ratajczak J., and Ratajczak M.Z. A population of very small embryonic-like (VSEL) CXCR4(+)SSEA-1(+)Oct-4+ stem cells identified in adult bone marrow. Leukemia 20 (2006) 857-869
15. Lamba D.A., Karl M.O., Ware C.B., and Reh T.A. Efficient generation of retinal progenitor cells from human embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 12769-12774
16. Loewenstein J.I., Montezuma S.R., and Rizzo III J.F. Outer retinal degeneration: an electronic retinal prosthesis as a treatment strategy. Arch. Ophthalmol. 122 (2004) 587-596
17. MacLaren R.E., Pearson R.A., MacNeil A., Douglas R.H., Salt T.E., Akimoto M., Swaroop A., Sowden J.C., and Ali R.R. Retinal repair by transplantation of photoreceptor precursors. Nature 444 (2006) 203-207
18. Schanze T., Hesse L., Lau C., Greve N., Haberer W., Kammer S., Doerge T., Rentzos A., and Stieglitz T. An optically powered single-channel stimulation implant as test system for chronic biocompatibility and biostability of miniaturized retinal vision prostheses. IEEE Trans. Biomed. Eng. 54 (2007) 983-992
19. Yang J., Klassen H., Pries M., Wang W., and Nissen M.H. Aqueous humor enhances the proliferation of rat retinal precursor cells in culture, and this effect is partially reproduced by ascorbic acid. Stem Cells 24 (2006) 2766-2775
20. Yang P., Seiler M.J., Aramant R.B., and Whittemore S.R. Differential lineage restriction of rat retinal progenitor cells in vitro and in vivo. J. Neurosci. Res. 69 (2002) 466-476
21. Yang P., Seiler M.J., Aramant R.B., and Whittemore S.R. In vitro isolation and expansion of human retinal progenitor cells. Exp. Neurol. 177 (2002) 326-331
22. Young R.W. Cell differentiation in the retina of the mouse. Anat. Rec. 212 (1985) 199-205
23. Zhang Y., Klassen H., Tucker B., Perez M.R., and Young M.J. CNS progenitor cells promote a permissive environment for neurite outgrowth via a matrix metalloproteinase-2-dependent mechanism. J. Neurosci. 27 (2007) 4499-4506