메뉴 건너뛰기




Volumn 7, Issue SUPPL. 1, 2009, Pages 103-106

Epidemiology and management of bleeding in patients using vitamin K antagonists

Author keywords

Coumadin; Hemorrhage; Vitamin K antagonists; Warfarin

Indexed keywords

ACENOCOUMAROL; ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; ANTIVITAMIN K; CLOPIDOGREL; CYTOCHROME P450 2C9; FRESH FROZEN PLASMA; NONSTEROID ANTIINFLAMMATORY AGENT; PHENPROCOUMON; PLACEBO; PROTHROMBIN COMPLEX; RECOMBINANT BLOOD CLOTTING FACTOR 7A; VITAMIN K GROUP; WARFARIN;

EID: 67849103780     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2009.03389.x     Document Type: Review
Times cited : (15)

References (42)
  • 1
    • 34249821653 scopus 로고    scopus 로고
    • Prevention and treatment of major blood loss
    • Mannucci PM, Levi M. Prevention and treatment of major blood loss. N Engl J Med 2007; 356: 2301-11.
    • (2007) N Engl J Med , vol.356 , pp. 2301-2311
    • Mannucci, P.M.1    Levi, M.2
  • 2
    • 45949098057 scopus 로고    scopus 로고
    • Hemorrhagic complications of anticoagulant and thrombolytic treatment: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
    • Schulman S, Beyth RJ, Kearon C, Levine MN. Hemorrhagic complications of anticoagulant and thrombolytic treatment: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2008; 133: 257S-98S.
    • (2008) Chest , vol.133
    • Schulman, S.1    Beyth, R.J.2    Kearon, C.3    Levine, M.N.4
  • 3
    • 33747599590 scopus 로고    scopus 로고
    • Adverse impact of bleeding on prognosis in patients with acute coronary syndromes
    • Eikelboom JW, Mehta SR, Anand SS, Xie C, Fox KA, Yusuf S. Adverse impact of bleeding on prognosis in patients with acute coronary syndromes. Circulation 2006; 114: 774-82.
    • (2006) Circulation , vol.114 , pp. 774-782
    • Eikelboom, J.W.1    Mehta, S.R.2    Anand, S.S.3    Xie, C.4    Fox, K.A.5    Yusuf, S.6
  • 4
    • 33846230041 scopus 로고    scopus 로고
    • Medium intensity oral anticoagulants versus aspirin after cerebral ischaemia of arterial origin (ESPRIT): A randomised controlled trial
    • Algra A. Medium intensity oral anticoagulants versus aspirin after cerebral ischaemia of arterial origin (ESPRIT): A randomised controlled trial. Lancet Neurol 2007; 6: 115-24.
    • (2007) Lancet Neurol , vol.6 , pp. 115-124
    • Algra, A.1
  • 5
    • 0025128956 scopus 로고
    • Trial of different intensities of anticoagulation in patients with prosthetic heart valves
    • Saour JN, Sieck JO, Mamo LA, Gallus AS. Trial of different intensities of anticoagulation in patients with prosthetic heart valves. N Engl J Med 1990; 322: 428-32.
    • (1990) N Engl J Med , vol.322 , pp. 428-432
    • Saour, J.N.1    Sieck, J.O.2    Mamo, L.A.3    Gallus, A.S.4
  • 6
    • 0348109325 scopus 로고    scopus 로고
    • The optimal intensity of vitamin K antagonists in patients with mechanical heart valves: A meta-analysis
    • Vink R, Kraaijenhagen RA, Hutten BA, Levi M. The optimal intensity of vitamin K antagonists in patients with mechanical heart valves: A meta-analysis. J.Am Coll Cardiol 2003; 42: 2042-8.
    • (2003) J. Am Coll Cardiol , vol.42 , pp. 2042-2048
    • Vink, R.1    Kraaijenhagen, R.A.2    Hutten, B.A.3    Levi, M.4
  • 7
    • 0028343127 scopus 로고
    • Risk factors for intracranial hemorrhage in outpatients taking warfarin
    • Hylek EM, Singer DE. Risk factors for intracranial hemorrhage in outpatients taking warfarin. Ann Intern Med 1994; 120: 897-902.
    • (1994) Ann Intern Med , vol.120 , pp. 897-902
    • Hylek, E.M.1    Singer, D.E.2
  • 10
    • 45949103309 scopus 로고    scopus 로고
    • Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
    • Ansell J, Hirsh J, Hylek E, Jacobson A, Crowther M, Palareti G. Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2008; 133: 160S-98S.
    • (2008) Chest , vol.133
    • Ansell, J.1    Hirsh, J.2    Hylek, E.3    Jacobson, A.4    Crowther, M.5    Palareti, G.6
  • 11
    • 0036846212 scopus 로고    scopus 로고
    • A randomised controlled trial of patient self management of oral anticoagulation treatment compared with primary care management
    • Fitzmaurice DA, Murray ET, Gee KM, Allan TF, Hobbs FD. A randomised controlled trial of patient self management of oral anticoagulation treatment compared with primary care management. J. Clin Pathol 2002; 55: 845-9.
    • (2002) J. Clin Pathol , vol.55 , pp. 845-849
    • Fitzmaurice, D.A.1    Murray, E.T.2    Gee, K.M.3    Allan, T.F.4    Hobbs, F.D.5
  • 12
    • 0032494736 scopus 로고    scopus 로고
    • Multicentre randomised study of computerised anticoagulant dosage. European Concerted Action on Anticoagulation
    • Poller L, Shiach CR, MacCallum PK. Multicentre randomised study of computerised anticoagulant dosage. European Concerted Action on Anticoagulation. Lancet 1998; 352: 1505-9.
    • (1998) Lancet , vol.352 , pp. 1505-1509
    • Poller, L.1    Shiach, C.R.2    MacCallum, P.K.3
  • 13
    • 0034046908 scopus 로고    scopus 로고
    • A computer generated induction system for hospitalized patients starting on oral anticoagulant therapy
    • Ageno W, Johnson J, Nowacki B, Turpie AG. A computer generated induction system for hospitalized patients starting on oral anticoagulant therapy. Thromb Haemost 2000; 83: 849-52.
    • (2000) Thromb Haemost , vol.83 , pp. 849-852
    • Ageno, W.1    Johnson, J.2    Nowacki, B.3    Turpie, A.G.4
  • 14
    • 52049094618 scopus 로고    scopus 로고
    • Self-management of anticoagulation
    • Levi M. Self-management of anticoagulation. Expert Rev Cardiovasc Ther 2008; 6: 979-85.
    • (2008) Expert Rev Cardiovasc Ther , vol.6 , pp. 979-985
    • Levi, M.1
  • 15
    • 0032964460 scopus 로고    scopus 로고
    • Safety of treatment with oral anticoagulants in the elderly. A systematic review
    • Hutten BA, Lensing AW, Kraaijenhagen RA, Prins MH. Safety of treatment with oral anticoagulants in the elderly. A systematic review. Drugs Aging 1999; 14: 303-12.
    • (1999) Drugs Aging , vol.14 , pp. 303-312
    • Hutten, B.A.1    Lensing, A.W.2    Kraaijenhagen, R.A.3    Prins, M.H.4
  • 16
    • 19644400842 scopus 로고    scopus 로고
    • Advanced age, anticoagulation intensity, and risk for intracranial hemorrhage among patients taking warfarin for atrial fibrillation
    • Fang MC, Chang Y, Hylek EM, et al. Advanced age, anticoagulation intensity, and risk for intracranial hemorrhage among patients taking warfarin for atrial fibrillation. Ann Intern Med 2004; 141: 745-52.
    • (2004) Ann Intern Med , vol.141 , pp. 745-752
    • Fang, M.C.1    Chang, Y.2    Hylek, E.M.3
  • 17
    • 0037012465 scopus 로고    scopus 로고
    • Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy
    • Higashi MK, Veenstra DL, Kondo LM, et al. Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy. JAMA 2002; 287: 1690-8.
    • (2002) JAMA , vol.287 , pp. 1690-1698
    • Higashi, M.K.1    Veenstra, D.L.2    Kondo, L.M.3
  • 19
    • 47149099551 scopus 로고    scopus 로고
    • Bleeding in patients receiving vitamin K antagonists who would have been excluded from trials on which the indication for anticoagulation was based
    • Levi M, Hovingh GK, Cannegieter SC, Vermeulen M, Buller HR, Rosendaal FR. Bleeding in patients receiving vitamin K antagonists who would have been excluded from trials on which the indication for anticoagulation was based. Blood 2008; 111: 4471-6.
    • (2008) Blood , vol.111 , pp. 4471-4476
    • Levi, M.1    Hovingh, G.K.2    Cannegieter, S.C.3    Vermeulen, M.4    Buller, H.R.5    Rosendaal, F.R.6
  • 20
    • 0032991899 scopus 로고    scopus 로고
    • Increased risk of intracranial hemorrhage when aspirin is combined with warfarin: A meta-analysis and hypothesis
    • Hart RG, Benavente O, Pearce LA. Increased risk of intracranial hemorrhage when aspirin is combined with warfarin: A meta-analysis and hypothesis. Cerebrovasc Dis 1999; 9: 215-7.
    • (1999) Cerebrovasc Dis , vol.9 , pp. 215-217
    • Hart, R.G.1    Benavente, O.2    Pearce, L.A.3
  • 21
    • 23644443663 scopus 로고    scopus 로고
    • Warfarin plus aspirin after myocardial infarction or the acute coronary syndrome
    • Rothberg MB, Celestin C, Fiore LD, Lawler E, Cook JR. Warfarin plus aspirin after myocardial infarction or the acute coronary syndrome. Ann Intern Med 2005; 143: 241-50.
    • (2005) Ann Intern Med , vol.143 , pp. 241-250
    • Rothberg, M.B.1    Celestin, C.2    Fiore, L.D.3    Lawler, E.4    Cook, J.R.5
  • 22
    • 33749681586 scopus 로고    scopus 로고
    • Use of single and combined antithrombotic therapy and risk of serious upper gastrointestinal bleeding: Population based case-control study
    • Hallas J, Dall M, Andries A, et al. Use of single and combined antithrombotic therapy and risk of serious upper gastrointestinal bleeding: Population based case-control study. BMJ 2006; 333: 726.
    • (2006) BMJ , vol.333 , pp. 726
    • Hallas, J.1    Dall, M.2    Andries, A.3
  • 23
    • 17444454171 scopus 로고    scopus 로고
    • Upper gastrointestinal bleeding among users of NSAIDs: A population-based cohort study in Denmark
    • Mellemkjaer L, Blot WJ, Sorensen HT, et al. Upper gastrointestinal bleeding among users of NSAIDs: A population-based cohort study in Denmark. Br J Clin Pharmacol 2002; 53: 173-81.
    • (2002) Br J Clin Pharmacol , vol.53 , pp. 173-181
    • Mellemkjaer, L.1    Blot, W.J.2    Sorensen, H.T.3
  • 24
    • 12444264226 scopus 로고    scopus 로고
    • Risk of upper gastrointestinal hemorrhage in warfarin users treated with nonselective NSAIDs or COX-2 inhibitors
    • Battistella M, Mamdami MM, Juurlink DN, Rabeneck L, Laupacis A. Risk of upper gastrointestinal hemorrhage in warfarin users treated with nonselective NSAIDs or COX-2 inhibitors. Arch Intern Med 2005; 165: 189-92.
    • (2005) Arch Intern Med , vol.165 , pp. 189-192
    • Battistella, M.1    Mamdami, M.M.2    Juurlink, D.N.3    Rabeneck, L.4    Laupacis, A.5
  • 25
    • 11444261579 scopus 로고    scopus 로고
    • External validity of randomised controlled trials: 'To whom do the results of this trial apply?'
    • Rothwell PM. External validity of randomised controlled trials: 'to whom do the results of this trial apply?'. Lancet 2005; 365: 82-93.
    • (2005) Lancet , vol.365 , pp. 82-93
    • Rothwell, P.M.1
  • 26
    • 57349109888 scopus 로고    scopus 로고
    • Bleeding complications in patients on anticoagulants who would have been disqualified for clinical trials
    • Levi M, Hovingh K. Bleeding complications in patients on anticoagulants who would have been disqualified for clinical trials. Thromb Haemost 2008; 100: 1047-51.
    • (2008) Thromb Haemost , vol.100 , pp. 1047-1051
    • Levi, M.1    Hovingh, K.2
  • 27
    • 9744241689 scopus 로고    scopus 로고
    • Results of an open-label, prospective study of anticoagulant therapy for atrial fibrillation in an outpatient anticoagulation clinic
    • Abdelhafiz AH, Wheeldon NM. Results of an open-label, prospective study of anticoagulant therapy for atrial fibrillation in an outpatient anticoagulation clinic. Clin Ther 2004; 26: 1470-8.
    • (2004) Clin Ther , vol.26 , pp. 1470-1478
    • Abdelhafiz, A.H.1    Wheeldon, N.M.2
  • 28
    • 0035571203 scopus 로고    scopus 로고
    • Outcomes in the management of atrial fibrillation: Clinical trial results can apply in practice
    • Jackson SL, Peterson GM, Vial JH, Daud R, Ang SY. Outcomes in the management of atrial fibrillation: Clinical trial results can apply in practice. Intern Med J 2001; 31: 329-36.
    • (2001) Intern Med J , vol.31 , pp. 329-336
    • Jackson, S.L.1    Peterson, G.M.2    Vial, J.H.3    Daud, R.4    Ang, S.Y.5
  • 29
    • 63149114682 scopus 로고    scopus 로고
    • Emergency reversal of antithrombotic treatment
    • Levi M. Emergency reversal of antithrombotic treatment. Intern Emerg Med 2009; 4: 137-45.
    • (2009) Intern Emerg Med , vol.4 , pp. 137-145
    • Levi, M.1
  • 30
    • 33747198471 scopus 로고    scopus 로고
    • Treatment of coumarin-associated coagulopathy
    • Dentali F, Ageno W, Crowther M. Treatment of coumarin-associated coagulopathy. J. Thromb Haemost 2006; 4: 1853-63.
    • (2006) J. Thromb Haemost , vol.4 , pp. 1853-1863
    • Dentali, F.1    Ageno, W.2    Crowther, M.3
  • 31
    • 61449121171 scopus 로고    scopus 로고
    • Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin
    • Crowther MA, Ageno W, Garcia D, et al. Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin. Ann Intern Med 2009; 150: 293-300.
    • (2009) Ann Intern Med , vol.150 , pp. 293-300
    • Crowther, M.A.1    Ageno, W.2    Garcia, D.3
  • 32
    • 0037143569 scopus 로고    scopus 로고
    • Oral vitamin K lowers the international normalized ratio more rapidly than subcutaneous vitamin K in the treatment of warfarin-associated coagulopathy. A randomized, controlled trial
    • Crowther MA, Douketis JD, Schnurr T, et al. Oral vitamin K lowers the international normalized ratio more rapidly than subcutaneous vitamin K in the treatment of warfarin-associated coagulopathy. A randomized, controlled trial. Ann Intern Med 2002; 137: 251-4.
    • (2002) Ann Intern Med , vol.137 , pp. 251-254
    • Crowther, M.A.1    Douketis, J.D.2    Schnurr, T.3
  • 33
    • 0242592156 scopus 로고    scopus 로고
    • Comparison of oral vs intravenous phytonadione (vitamin K1) in patients with excessive anticoagulation: A prospective randomized controlled study
    • Lubetsky A, Yonath H, Olchovsky D, Loebstein R, Halkin H, Ezra D. Comparison of oral vs intravenous phytonadione (vitamin K1) in patients with excessive anticoagulation: A prospective randomized controlled study. Arch Intern Med 2003; 163: 2469-73.
    • (2003) Arch Intern Med , vol.163 , pp. 2469-2473
    • Lubetsky, A.1    Yonath, H.2    Olchovsky, D.3    Loebstein, R.4    Halkin, H.5    Ezra, D.6
  • 35
    • 3242793451 scopus 로고    scopus 로고
    • Management of coumarin-associated coagulopathy in the non-bleeding patient: A systematic review
    • Dentali F, Ageno W. Management of coumarin-associated coagulopathy in the non-bleeding patient: A systematic review. Haematologica 2004; 89: 857-62.
    • (2004) Haematologica , vol.89 , pp. 857-862
    • Dentali, F.1    Ageno, W.2
  • 36
    • 33845962889 scopus 로고    scopus 로고
    • Treatment of warfarin-associated intracerebral hemorrhage: Literature review and expert opinion
    • Aguilar MI, Hart RG, Kase CS, et al. Treatment of warfarin-associated intracerebral hemorrhage: Literature review and expert opinion. Mayo Clin Proc 2007; 82: 82-92.
    • (2007) Mayo Clin Proc , vol.82 , pp. 82-92
    • Aguilar, M.I.1    Hart, R.G.2    Kase, C.S.3
  • 37
    • 33746787177 scopus 로고    scopus 로고
    • Individualized dosing regimen for prothrombin complex concentrate more effective than standard treatment in the reversal of oral anticoagulant therapy
    • Van AL, Eijkhout HW, Kamphuis JS, et al. Individualized dosing regimen for prothrombin complex concentrate more effective than standard treatment in the reversal of oral anticoagulant therapy. Thromb Res 2006; 118: 313-20.
    • (2006) Thromb Res , vol.118 , pp. 313-320
    • Van, A.L.1    Eijkhout, H.W.2    Kamphuis, J.S.3
  • 38
    • 33645648065 scopus 로고    scopus 로고
    • Urgent reversal of warfarin with prothrombin complex concentrate: Where are the evidence-based data?
    • Kessler CM. Urgent reversal of warfarin with prothrombin complex concentrate: Where are the evidence-based data? J Thromb Haemost 2006; 4: 963-6.
    • (2006) J Thromb Haemost , vol.4 , pp. 963-966
    • Kessler, C.M.1
  • 39
    • 40949148098 scopus 로고    scopus 로고
    • Prothrombin complex concentrate (Beriplex P/N) for emergency anticoagulation reversal
    • Pabinger I, Brenner B, Kalina U, Knaub S, Nagy A, Ostermann H. Prothrombin complex concentrate (Beriplex P/N) for emergency anticoagulation reversal. J Thromb Haemost 2008; 6: 622-31.
    • (2008) J Thromb Haemost , vol.6 , pp. 622-631
    • Pabinger, I.1    Brenner, B.2    Kalina, U.3    Knaub, S.4    Nagy, A.5    Ostermann, H.6
  • 40
    • 34548214668 scopus 로고    scopus 로고
    • Disseminated intravascular coagulation
    • Levi M. Disseminated intravascular coagulation. Crit Care Med 2007; 35: 2191-5.
    • (2007) Crit Care Med , vol.35 , pp. 2191-2195
    • Levi, M.1
  • 41
    • 33746712273 scopus 로고    scopus 로고
    • Reversal of elevated international normalized ratios and bleeding with low-dose recombinant activated factor VII in patients receiving warfarin
    • Dager WE, King JH, Regalia RC, et al. Reversal of elevated international normalized ratios and bleeding with low-dose recombinant activated factor VII in patients receiving warfarin. Pharmacotherapy 2006; 26: 1091-8.
    • (2006) Pharmacotherapy , vol.26 , pp. 1091-1098
    • Dager, W.E.1    King, J.H.2    Regalia, R.C.3
  • 42
    • 0042125355 scopus 로고    scopus 로고
    • Reversal of the International Normalized Ratio with recombinant activated factor VII in central nervous system bleeding during warfarin thromboprophylaxis
    • Sorensen B, Johansen P, Nielsen GL, Sorensen JC, Ingerslev J. Reversal of the International Normalized Ratio with recombinant activated factor VII in central nervous system bleeding during warfarin thromboprophylaxis. Blood Coagul Fibrinolysis 2003; 14: 469-77.
    • (2003) Blood Coagul Fibrinolysis , vol.14 , pp. 469-477
    • Sorensen, B.1    Johansen, P.2    Nielsen, G.L.3    Sorensen, J.C.4    Ingerslev, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.