Production of andrographolide from adventitious root cultures of Andrographis paniculata

Current Science

Volumn 96, Issue 5, 2009, Pages 694-697

  Praveen, N ^a   Manohar, S H ^a   Naik, P M ^a   Nayeem, A ^a   Jeong, J H ^b   Murthy, H N ^a  

^a KARNATAK UNIVERSITY   (India)

^b Department of Medicinal Resources and Horticulture   (South Korea)

Author keywords

Adventitious roots; Andrographis paniculata; Andrographolide; Suspension cultures

Indexed keywords

ANDROGRAPHIS PANICULATA;

EID: 67849102562     PISSN: 00113891     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Sharma, A., Singh, R. T., Sehgal, V. and Handa, S. S., Antihepatotoxic activity of some plants used in herbal formulation. Fitoterapia, 1991, 62, 131-138.
2. Tang, W. and Eisenbrand, G., Chinese Drugs of Plant Origin, Springer-Verlag, Berlin, 1992, pp. 97-103.
3. Mishra, P., Pal, N. L., Guru, P. Y., Katiyar, J. C. and Srivastava Tandon, J. S., Antimalarial activity of Andrographis paniculata (Kalmegh) against Plasmodium berghei NK 65 in Mastomys natalensis. Int. J. Pharmacogn., 1992, 30, 263-274.
4. Saxena, S., Jain, D. C., Bhakuni, R. A. and Sharma, R. P., Chemistry and pharmacology of Andrographis species. Indian Drugs, 1998, 35, 458-467.
5. Kumar, R. A., Sridevi, K., Kumar, N. V., Nanduri, S. and Rajagopal, S., Anticancer and immunostimulatory compounds from Andrographis paniculata. J. Ethnopharmacol., 2004, 92, 291-295.
6. Verpoorte, R., van der Heijden, R., ten Hoopen, H. J. G. and Memelink, J., Metabolic engineering of plant secondary metabolite pathways for the production of fine chemicals. Biotechnol. Lett., 1999, 21, 467-479.
7. Dornenburg, H. and Knorr, D., Strategies for improvement of secondary metabolite production in plant cell cultures. Enzyme Microb. Technol., 1995, 17, 674-684.
8. Rao, S. R. and Ravishankar, K. A., Plant cell cultures: chemical factories of secondary metabolites. Biotechnol. Adv., 2002, 20, 101-153.
9. Butcher, D. N. and Connolly, J. D., An investigation of factors which influence the production of abnormal terpenoids by callus cultures of Andrographis paniculata Nees. J. Exp. Bot., 1971, 22, 315-322.
10. Murashige, T. and Skoog, F., A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiol. Plant., 1962, 15, 474-497.
11. Jain, D. C., Gupta, M. M. and Saxena, S. K., LC analysis of hepatoprotective diterpenoids from Andrographis paniculata. J. Pharm. Biomed. Anal., 2000, 22, 705-709.
12. Klerk, G. J. D., Arnholdt-Schmitt, B., Lieberei, R. and Neumnann, K. H., Regeneration of roots, shoots and embryos: physiological, biochemical and molecular aspects. Biol. Plant., 1997, 39, 53-66.
13. Gao, X., Zhu, C., Jia, W., Gao, W., Qiu, M., Zhang, Y. and Xiao, P., Induction and characterization of adventitious roots directly from leaf explants of Panax notoginseng. Biotechnol. Lett., 2005, 27, 1771-1775.
14. Wu, C. H., Murthy, H. N., Hahn, E. J. and Paek, K. Y., Largescale cultivation of adventitious roots of Echinacea purpurea in airlift bioreactors for the production of chichoric acid, chlorogenic acid and caftaric acid. Biotechnol. Lett., 2007, 29, 1179-1182.