Conformational recovery and preservation of protein nature from heat-induced denaturation by water-soluble phospholipid polymer conjugation

Biomaterials

Volumn 30, Issue 28, 2009, Pages 4859-4867

  Seo, Ji Hun ^a   Matsuno, Ryosuke ^a   Lee, Yan ^a,b   Takai, Madoka ^a   Ishihara, Kazuhiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Bioconjugation; Conformation change; Enzyme; Phospholipid polymer; Protein

Indexed keywords

2-METHACRYLOYLOXYETHYL PHOSPHORYLCHOLINE; ATOM TRANSFER; BIOCONJUGATION; CIRCULAR DICHROISM; CONFORMATION CHANGE; CONFORMATIONAL CHANGE; EFFECT OF WATER; FLUORESCENCE STUDIES; PHOSPHOLIPID POLYMER; PHOSPHOLIPID POLYMERS; PROTEIN ACTIVITY; SECONDARY AND TERTIARY STRUCTURES; WATER-SOLUBLE PHOSPHOLIPID POLYMERS;

ATOM TRANSFER RADICAL POLYMERIZATION; DICHROISM; ENZYMES; FREE RADICAL REACTIONS; FUNCTIONAL POLYMERS; PHOSPHOLIPIDS; POLYMERS;

ORGANIC POLYMERS;

BOVINE SERUM ALBUMIN; POLY(2 METHACRYLOYLOXYETHYLPHOSPHORYLCHOLINE); POLYMER; UNCLASSIFIED DRUG;

ARTICLE; CIRCULAR DICHROISM; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONJUGATION; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; HEAT STRESS; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN FUNCTION; PROTEIN STRUCTURE;

ANIMALS; CATTLE; DISULFIDES; HOT TEMPERATURE; METHACRYLATES; MURAMIDASE; PHOSPHORYLCHOLINE; PROTEIN CONFORMATION; PROTEIN DENATURATION; PYRIDINES; SERUM ALBUMIN, BOVINE;

EID: 67849090379     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.05.080     Document Type: Article

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