A dianionic Phosphorane Intermediate and transition states in an associative AN+DN mechanism for the ribonucleaseA hydrolysis reaction

Journal of the American Chemical Society

Volumn 131, Issue 11, 2009, Pages 3869-3871

  Elsässer, Brigitta ^a   Valiev, Marat ^a   Weare, John H ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL REACTIONS; BOND ORDERS; CATALYTIC ACIDS; CATALYTIC SITES; CONSERVED RESIDUES; ENERGY ESTIMATES; HYDROLYSIS REACTION; INTERMEDIATE STATE; P-O BONDS; PENTACOORDINATED; PHOSPHODIESTER BONDS; PHOSPHORANE; PHOSPHORYL TRANSFER; REACTION MECHANISM; REACTION PATHS; RELATIVE POSITIONING; THEORETICAL APPROACH; TRANSITION STATE;

ENZYMES; HYDROLYSIS; NUCLEIC ACIDS; PROTONS; RNA; SUGAR (SUCROSE); SUGARS;

PROTON TRANSFER;

PHOSPHORANE DERIVATIVE; RIBONUCLEASE A; RNA; PANCREATIC RIBONUCLEASE;

AB INITIO CALCULATION; ALGORITHM; ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; ENERGY; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; HYDROLYSIS; QUANTUM CHEMISTRY; QUANTUM MECHANICS; REACTION ANALYSIS; CHEMISTRY; THERMODYNAMICS;

HYDROLYSIS; MODELS, MOLECULAR; PHOSPHORANES; RIBONUCLEASE, PANCREATIC; THERMODYNAMICS;

EID: 67849089048     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja807940y     Document Type: Article

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