메뉴 건너뛰기




Volumn 4, Issue 1, 2009, Pages 42-51

Do antiretrovirals reduce the risk of non-AIDS-defining malignancies?

Author keywords

Antiretroviral therapy; HIV; Immunodeficiency; Malignancy

Indexed keywords

ANTIRETROVIRUS AGENT; ATAZANAVIR; INDINAVIR; NELFINAVIR; PLACEBO; PROTEINASE INHIBITOR; RALTEGRAVIR; RITONAVIR; SAQUINAVIR; VICRIVIROC;

EID: 67849084535     PISSN: 1746630X     EISSN: 17466318     Source Type: Journal    
DOI: 10.1097/COH.0b013e32831a9875     Document Type: Review
Times cited : (18)

References (73)
  • 1
    • 34548410922 scopus 로고    scopus 로고
    • AIDS-defining and non-AIDS-defining malignancies: Cancer occurrence in the antiretroviral therapy era
    • DOI 10.1097/CCO.0b013e3282c8c90d, PII 0000162220070900000006
    • Silverberg MJ, Abrams DI. AIDS-defining and non-AIDS-defining malignancies: cancer occurrence in the antiretroviral therapy era. Curr Opin Oncol 2007; 19:446-451. (Pubitemid 47356600)
    • (2007) Current Opinion in Oncology , vol.19 , Issue.5 , pp. 446-451
    • Silverberg, M.J.1    Abrams, D.I.2
  • 4
    • 0034669127 scopus 로고    scopus 로고
    • Highly active antiretroviral therapy and incidence of cancer in human immunodeficiency virus-infected adults
    • International Collaboration on HIV and Cancer
    • International Collaboration on HIV and Cancer. Highly active antiretroviral therapy and incidence of cancer in human immunodeficiency virus-infected adults. J Natl Cancer Inst 2000; 92:1823-1830
    • (2000) J Natl Cancer Inst , vol.92 , pp. 1823-1830
  • 5
    • 7644227284 scopus 로고    scopus 로고
    • Trends in AIDS-defining and non-AIDS-defining malignancies among HIV-infected patients: 1989-2002
    • Bedimo R, Chen RY, Accortt NA, et al. Trends in AIDS-defining and non-AIDS-defining malignancies among HIV-infected patients: 1989-2002. Clin Infect Dis 2004; 39:1380-1384.
    • (2004) Clin Infect Dis , vol.39 , pp. 1380-1384
    • Bedimo, R.1    Chen, R.Y.2    Accortt, N.A.3
  • 6
    • 33746773667 scopus 로고    scopus 로고
    • Trends in cancer risk among people with AIDS in the United States 1980-2002
    • Engels EA, Pfeiffer RM, Goedert JJ, et al. Trends in cancer risk among people with AIDS in the United States 1980-2002. AIDS 2006; 20:1645-1654.
    • (2006) AIDS , vol.20 , pp. 1645-1654
    • Engels, E.A.1    Pfeiffer, R.M.2    Goedert, J.J.3
  • 7
    • 0037436198 scopus 로고    scopus 로고
    • HIV-related lung cancer in the era of highly active antiretroviral therapy
    • DOI 10.1097/00002030-200302140-00011
    • Bower M, Powles T, Nelson M, et al. HIV-related lung cancer in the era of highly active antiretroviral therapy. AIDS 2003; 17:371-375. (Pubitemid 36230918)
    • (2003) AIDS , vol.17 , Issue.3 , pp. 371-375
    • Bower, M.1    Powles, T.2    Nelson, M.3    Shah, P.4    Cox, S.5    Mandelia, S.6    Gazzard, B.7
  • 9
    • 17744393024 scopus 로고    scopus 로고
    • Increased incidence of squamous cell anal cancer among men with AIDS in the era of highly active antiretroviral therapy
    • DOI 10.1097/01.olq.0000162366.60245.02
    • Diamond C, Taylor TH, Aboumrad T, et al. Increased incidence of squamous cell anal cancer among men with AIDS in the era of highly active antiretroviral therapy. Sex Transm Dis 2005; 32:314-320. (Pubitemid 40578072)
    • (2005) Sexually Transmitted Diseases , vol.32 , Issue.5 , pp. 314-320
    • Diamond, C.1    Taylor, T.H.2    Aboumrad, T.3    Bringman, D.4    Anton-Culver, H.5
  • 10
    • 55849128874 scopus 로고    scopus 로고
    • Changing incidence of AIDS-related Kaposi sarcoma and non-Hodgkin lymphoma in Ontario, Canada
    • Epub ahead of print
    • Bahl S, Theis B, Nishri D, Marrett LD. Changing incidence of AIDS-related Kaposi sarcoma and non-Hodgkin lymphoma in Ontario, Canada. Cancer Causes Control 2008 [Epub ahead of print].
    • (2008) Cancer Causes Control
    • Bahl, S.1    Theis, B.2    Nishri, D.3    Marrett, L.D.4
  • 12
    • 50249090040 scopus 로고    scopus 로고
    • Kaposi sarcoma incidence in the Swiss HIV Cohort Study before and after highly active antiretroviral therapy
    • Franceschi S, Maso LD, Rickenbach M, et al. Kaposi sarcoma incidence in the Swiss HIV Cohort Study before and after highly active antiretroviral therapy. Br J Cancer 2008; 99:800-804.
    • (2008) Br J Cancer , vol.99 , pp. 800-804
    • Franceschi, S.1    Maso, L.D.2    Rickenbach, M.3
  • 13
    • 2642570047 scopus 로고    scopus 로고
    • The changing pattern of Kaposi sarcoma in patients with HIV, 1994-2003: The EuroSIDA Study
    • Mocroft A, Kirk O, Clumeck N, et al. The changing pattern of Kaposi sarcoma in patients with HIV, 1994-2003: the EuroSIDA Study. Cancer 2004; 100:2644-2654.
    • (2004) Cancer , vol.100 , pp. 2644-2654
    • Mocroft, A.1    Kirk, O.2    Clumeck, N.3
  • 14
    • 37549064318 scopus 로고    scopus 로고
    • Non-Hodgkin lymphoma incidence in the Swiss HIV Cohort Study before and after highly active antiretroviral therapy
    • Polesel J, Clifford GM, Rickenbach M, et al. Non-Hodgkin lymphoma incidence in the Swiss HIV Cohort Study before and after highly active antiretroviral therapy. AIDS 2008; 22:301-306.
    • (2008) AIDS , vol.22 , pp. 301-306
    • Polesel, J.1    Clifford, G.M.2    Rickenbach, M.3
  • 15
    • 50649114254 scopus 로고    scopus 로고
    • Effect of HAART on incident cancer and noncancer AIDS events among male HIV seroconverters
    • Shiels MS, Cole SR, Wegner S, et al. Effect of HAART on incident cancer and noncancer AIDS events among male HIV seroconverters. J Acquir Immune Defic Syndr 2008; 48:485-490.
    • (2008) J Acquir Immune Defic Syndr , vol.48 , pp. 485-490
    • Shiels, M.S.1    Cole, S.R.2    Wegner, S.3
  • 16
    • 33845237838 scopus 로고    scopus 로고
    • Hodgkin lymphoma and immunodefi- Ciency in persons with HIV/AIDS
    • Biggar RJ, Jaffe ES, Goedert JJ, et al. Hodgkin lymphoma and immunodefi- ciency in persons with HIV/AIDS. Blood 2006; 108:3786-3791.
    • (2006) Blood , vol.108 , pp. 3786-3791
    • Biggar, R.J.1    Jaffe, E.S.2    Goedert, J.J.3
  • 18
    • 0035760292 scopus 로고    scopus 로고
    • Non-Hodgkin lymphoma in HIVinfected patients in the era of highly active antiretroviral therapy
    • Kirk O, Pedersen C, Cozzi-Lepri A, et al. Non-Hodgkin lymphoma in HIVinfected patients in the era of highly active antiretroviral therapy. Blood 2001; 98:3406-3412.
    • (2001) Blood , vol.98 , pp. 3406-3412
    • Kirk, O.1    Pedersen, C.2    Cozzi-Lepri, A.3
  • 20
    • 0003248215 scopus 로고    scopus 로고
    • AIDS across Europe, 1994-1998: The EuroSIDA study
    • Mocroft A, Katlama C, Johnson AM, et al. AIDS across Europe, 1994-1998: the EuroSIDA study. Lancet 2000; 356:291-296.
    • (2000) Lancet , vol.356 , pp. 291-296
    • Mocroft, A.1    Katlama, C.2    Johnson, A.M.3
  • 21
    • 40749090830 scopus 로고    scopus 로고
    • The shifting pattern of cause-specific mortality in a cohort of human immunodeficiency virus-infected and noninfected injecting drug users
    • The above article is unique in that cause-specific mortality rates were compared in HIV-infected and HIV-uninfected injection drug users
    • Ferreros I, Lumbreras B, Hurtado I, et al. The shifting pattern of cause-specific mortality in a cohort of human immunodeficiency virus-infected and noninfected injecting drug users. Addiction 2008; 103:651-659. The above article is unique in that cause-specific mortality rates were compared in HIV-infected and HIV-uninfected injection drug users.
    • (2008) Addiction , vol.103 , pp. 651-659
    • Ferreros, I.1    Lumbreras, B.2    Hurtado, I.3
  • 22
    • 44149123399 scopus 로고    scopus 로고
    • Incidence of types of cancer among HIV-infected persons compared with the general population in the United States, 1992-2003
    • The above is a large cohort study evaluating risk factors and trends in cancer among HIV-infected patients and is one of few studies to evaluate NADM risk with respect to both calendar year and individual ART use
    • Patel P, Hanson DL, Sullivan PS, et al. Incidence of types of cancer among HIV-infected persons compared with the general population in the United States, 1992-2003. Ann Intern Med 2008; 148:728-736. The above is a large cohort study evaluating risk factors and trends in cancer among HIV-infected patients and is one of few studies to evaluate NADM risk with respect to both calendar year and individual ART use.
    • (2008) Ann Intern Med , vol.148 , pp. 728-736
    • Patel, P.1    Hanson, D.L.2    Sullivan, P.S.3
  • 23
    • 43949097900 scopus 로고    scopus 로고
    • Cancer risk in people infected with human immunodeficiency virus in the United States
    • The above is one of few cancer registry match studies to include both reported HIV and AIDS cases. Also evaluated association of NADMs with AIDS diagnosis and CD4 T-cell counts
    • Engels EA, Biggar RJ, Hall HI, et al. Cancer risk in people infected with human immunodeficiency virus in the United States. Int J Cancer 2008; 123:187-194. The above is one of few cancer registry match studies to include both reported HIV and AIDS cases. Also evaluated association of NADMs with AIDS diagnosis and CD4 T-cell counts.
    • (2008) Int J Cancer , vol.123 , pp. 187-194
    • Engels, E.A.1    Biggar, R.J.2    Hall, H.I.3
  • 24
    • 34447114504 scopus 로고    scopus 로고
    • The impact of highly active antiretroviral therapy on non-AIDS-defining cancers among adults with AIDS
    • DOI 10.1093/aje/kwm017
    • Hessol NA, Pipkin S, Schwarcz S, et al. The impact of highly active antiretroviral therapy on non-AIDS-defining cancers among adults with AIDS. Am J Epidemiol 2007; 165:1143-1153. The above is one of few studies to evaluate NADM risk with respect to both calendar year and individual ART use. Also unique in that few other AIDS Cancer registry match studies include data on individual ART use. (Pubitemid 47233717)
    • (2007) American Journal of Epidemiology , vol.165 , Issue.10 , pp. 1143-1153
    • Hessol, N.A.1    Pipkin, S.2    Schwarcz, S.3    Cress, R.D.4    Bacchetti, P.5    Scheer, S.6
  • 25
    • 39849097509 scopus 로고    scopus 로고
    • Incidence and outcomes of malignancy in the HAART era in an urban cohort of HIV-infected individuals
    • The above provides interesting analysis of NADM trends, clinical characteristics, and survival compared with patients with ADM
    • Long JL, Engels EA, Moore RD, Gebo KA. Incidence and outcomes of malignancy in the HAART era in an urban cohort of HIV-infected individuals. AIDS 2008; 22:489-496. The above provides interesting analysis of NADM trends, clinical characteristics, and survival compared with patients with ADM.
    • (2008) AIDS , vol.22 , pp. 489-496
    • Long, J.L.1    Engels, E.A.2    Moore, R.D.3    Gebo, K.A.4
  • 26
    • 50949100526 scopus 로고    scopus 로고
    • Marked increase in the incidence of invasive anal cancer among HIV-infected patients despite treatment with combination antiretroviral therapy
    • The above is the largest recent study to focus exclusively on anal cancer
    • Piketty C, Selinger-Leneman H, Grabar S, et al. Marked increase in the incidence of invasive anal cancer among HIV-infected patients despite treatment with combination antiretroviral therapy. AIDS 2008; 22:1203-1211. The above is the largest recent study to focus exclusively on anal cancer.
    • (2008) AIDS , vol.22 , pp. 1203-1211
    • Piketty, C.1    Selinger-Leneman, H.2    Grabar, S.3
  • 27
    • 33845961961 scopus 로고    scopus 로고
    • Elevated risk of lung cancer among people with AIDS
    • DOI 10.1097/QAD.0b013e3280118fca, PII 0000203020070111000011
    • Chaturvedi AK, Pfeiffer RM, Chang L, et al. Elevated risk of lung cancer among people with AIDS. AIDS 2007; 21:207-213. The above is a large and well designed US-based AIDS and cancer registry match study of lung cancer. Indirect adjustment used to control for smoking. (Pubitemid 46036929)
    • (2007) AIDS , vol.21 , Issue.2 , pp. 207-213
    • Chaturvedi, A.K.1    Pfeiffer, R.M.2    Chang, L.3    Goedert, J.J.4    Biggar, R.J.5    Engels, E.A.6
  • 28
    • 34250807781 scopus 로고    scopus 로고
    • HIV infection is associated with an increased risk for lung cancer, independent of smoking
    • DOI 10.1086/518606
    • Kirk GD, Merlo C, P OD, et al. HIV infection is associated with an increased risk for lung cancer, independent of smoking. Clin Infect Dis 2007; 45:103-110. Despite small numbers, provided comparison to HIV-uninfected injection drug users and had more complete adjustment for smoking compared with other studies. (Pubitemid 46984625)
    • (2007) Clinical Infectious Diseases , vol.45 , Issue.1 , pp. 103-110
    • Kirk, G.D.1    Merlo, C.2    O'Driscoll, P.3    Mehta, S.H.4    Galai, N.5    Vlahov, D.6    Samet, J.7    Engels, E.A.8
  • 29
    • 67849135353 scopus 로고    scopus 로고
    • Increasing incidence of prostate cancer in the Atlanta VA cohort study (HAVACS)
    • abstract. abstract 874. The above study evaluated both prostate cancer and prostate-specific antigen testing rates over time
    • Rimland D, Guest JL. Increasing incidence of prostate cancer in the Atlanta VA cohort study (HAVACS) [abstract]. In: 14th Conference on Retroviruses and Opportunistic Infections; 25-28 February 2007; Los Angeles, California; abstract 874. The above study evaluated both prostate cancer and prostate-specific antigen testing rates over time.
    • 14th Conference on Retroviruses and Opportunistic Infections; 25-28 February 2007; Los Angeles, California
    • Rimland, D.1    Guest, J.L.2
  • 32
    • 34548222243 scopus 로고    scopus 로고
    • Risk of cancers during interrupted antiretroviral therapy in the SMART study
    • DOI 10.1097/QAD.0b013e3282ed6338, PII 0000203020070912000015
    • Silverberg MJ, Neuhaus J, Bower M, et al. Risk of cancers during interrupted antiretroviral therapy in the SMART study. AIDS 2007; 21:1957-1963. This study has broad generalizability, given many countries involved, and is one of few randomized clinical trials to focus on incidence and risk factors for malignancies. (Pubitemid 47329772)
    • (2007) AIDS , vol.21 , Issue.14 , pp. 1957-1963
    • Silverberg, M.J.1    Neuhaus, J.2    Bower, M.3    Gey, D.4    Hatzakis, A.5    Henry, K.6    Hidalgo, J.7    Lourtau, L.8    Neaton, J.D.9    Tambussi, G.10    Abrams, D.I.11
  • 33
    • 67849089878 scopus 로고    scopus 로고
    • Immunodeficiency and risk of AIDS-defining and non-AIDS-defining cancers: ANRSCO3 Aquitaine Cohort, 1998 to 2006
    • abstract. abstract 15. A novel evaluation of duration exposed to low CD4+ T-cell counts
    • Bruyand M, Thiebaut R, Lawson-Ayayi S, et al. Immunodeficiency and risk of AIDS-defining and non-AIDS-defining cancers: ANRSCO3 Aquitaine Cohort, 1998 to 2006 [abstract]. In: 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston, Massachusetts: abstract 15. A novel evaluation of duration exposed to low CD4+ T-cell counts.
    • 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston, Massachusetts
    • Bruyand, M.1    Thiebaut, R.2    Lawson-Ayayi, S.3
  • 34
    • 67849118110 scopus 로고    scopus 로고
    • The impact of nelfinavir on cancer development among HIV-infected persons
    • abstract. abstract THPE0232. One of few studies to evaluate individual antiretrovirals on cancer risk
    • Crum-Cianflone N, Huppler Hullsiek K, Ganesan A, et al. The impact of nelfinavir on cancer development among HIV-infected persons [abstract]. In: 17th International AIDS Conference; 3-8 August 2008; Mexico City, Mexico: abstract THPE0232. One of few studies to evaluate individual antiretrovirals on cancer risk.
    • 17th International AIDS Conference; 3-8 August 2008; Mexico City, Mexico
    • Crum-Cianflone, N.1    Huppler Hullsiek, K.2    Ganesan, A.3
  • 36
    • 47949120697 scopus 로고    scopus 로고
    • Raltegravir with optimized background therapy for resistant HIV-1 infection
    • Steigbigel RT, Cooper DA, Kumar PN, et al. Raltegravir with optimized background therapy for resistant HIV-1 infection. N Engl J Med 2008; 359:339-354.
    • (2008) N Engl J Med , vol.359 , pp. 339-354
    • Steigbigel, R.T.1    Cooper, D.A.2    Kumar, P.N.3
  • 37
    • 50649085517 scopus 로고    scopus 로고
    • Incidence and epidemiology of anal cancer in the multicenter AIDS cohort study
    • Small numbers, but one of few studies to include HIV-uninfected controls for study of anal cancer and provided comprehensive evaluation of risk factors including sexual behaviors and smoking
    • D'Souza G, Wiley DJ, Li X, et al. Incidence and epidemiology of anal cancer in the multicenter AIDS cohort study. J Acquir Immune Defic Syndr 2008; 48:491-499. Small numbers, but one of few studies to include HIV-uninfected controls for study of anal cancer and provided comprehensive evaluation of risk factors including sexual behaviors and smoking.
    • (2008) J Acquir Immune Defic Syndr , vol.48 , pp. 491-499
    • D'Souza, G.1    Wiley, D.J.2    Li, X.3
  • 38
    • 0030731537 scopus 로고    scopus 로고
    • Complete remission of AIDS-related Kaposi's sarcoma associated with undetectable human herpesvirus-8 sequences during anti-HIV protease therapy [3]
    • Blum L, Pellet C, Agbalika F, et al. Complete remission of AIDS-related Kaposi's sarcoma associated with undetectable human herpesvirus-8 sequences during anti-HIV protease therapy. AIDS 1997; 11:1653-1655. (Pubitemid 27460259)
    • (1997) AIDS , vol.11 , Issue.13 , pp. 1653-1655
    • Blum, L.1    Pellet, C.2    Agbalika, F.3    Blanchard, G.4    Morel, P.5    Calvo, F.6    Lebbe, C.7
  • 39
    • 0032760627 scopus 로고    scopus 로고
    • Regression of AIDS-related Kaposi's sarcoma following antiretroviral therapy with protease inhibitors: Biological correlates of clinical outcome
    • Cattelan AM, Calabro ML, Aversa SM, et al. Regression of AIDS-related Kaposi's sarcoma following antiretroviral therapy with protease inhibitors: biological correlates of clinical outcome. Eur J Cancer 1999; 35:1809-1815.
    • (1999) Eur J Cancer , vol.35 , pp. 1809-1815
    • Cattelan, A.M.1    Calabro, M.L.2    Aversa, S.M.3
  • 40
    • 1842638271 scopus 로고    scopus 로고
    • Acquired immunodeficiency syndrome-related Kaposi's sarcoma regression after highly active antiretroviral therapy: Biologic correlates of clinical outcome
    • Cattelan AM, Calabro ML, Gasperini P, et al. Acquired immunodeficiency syndrome-related Kaposi's sarcoma regression after highly active antiretroviral therapy: biologic correlates of clinical outcome. J Natl Cancer Inst Monogr 2001; 28:44-49.
    • (2001) J Natl Cancer Inst Monogr , vol.28 , pp. 44-49
    • Cattelan, A.M.1    Calabro, M.L.2    Gasperini, P.3
  • 41
    • 0030753947 scopus 로고    scopus 로고
    • Reduction of Kaposi's sarcoma lesions following treatment of AIDS with ritonovir
    • Conant MA, Opp KM, Poretz D, Mills RG. Reduction of Kaposi's sarcoma lesions following treatment of AIDS with ritonovir. AIDS 1997; 11:1300-1301.
    • (1997) AIDS , vol.11 , pp. 1300-1301
    • Conant, M.A.1    Opp, K.M.2    Poretz, D.3    Mills, R.G.4
  • 42
    • 0032492955 scopus 로고    scopus 로고
    • Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma
    • DOI 10.1097/00002030-199807000-00002
    • Lebbe C, Blum L, Pellet C, et al. Clinical and biological impact of antiretroviral therapy with protease inhibitors on HIV-related Kaposi's sarcoma. AIDS 1998; 12:F45-F49. (Pubitemid 28190688)
    • (1998) AIDS , vol.12 , Issue.7
    • Lebbe, C.1    Blum, L.2    Pellet, C.3    Blanchard, G.4    Verola, O.5    Morel, P.6    Danne, O.7    Calvo, F.8
  • 43
    • 0031029007 scopus 로고    scopus 로고
    • Regression of AIDS-related Kaposi's sarcoma following treatment with an HIV-1 protease inhibitor [7]
    • Murphy M, Armstrong D, Sepkowitz KA, et al. Regression of AIDS-related Kaposi's sarcoma following treatment with an HIV-1 protease inhibitor. AIDS 1997; 11:261-262. (Pubitemid 27055419)
    • (1997) AIDS , vol.11 , Issue.2 , pp. 261-262
    • Murphy, M.1    Armstrong, D.2    Sepkowitz, K.A.3    Ahkami, R.N.4    Myskowski, P.L.5
  • 44
    • 0032750443 scopus 로고    scopus 로고
    • Highly active anti-retroviral therapy (HAART) prolongs time to treatment failure in Kaposi's sarcoma
    • DOI 10.1097/00002030-199910220-00014
    • Bower M, Fox P, Fife K, et al. Highly active antiretroviral therapy (HAART) prolongs time to treatment failure in Kaposi's sarcoma. AIDS 1999; 13:2105-2111. (Pubitemid 29509588)
    • (1999) AIDS , vol.13 , Issue.15 , pp. 2105-2111
    • Bower, M.1    Fox, P.2    Fife, K.3    Gill, J.4    Nelson, M.5    Gazzard, B.6
  • 46
    • 13244273520 scopus 로고    scopus 로고
    • Changing incidence and prognostic factors of survival in AIDS-related non-Hodgkin's lymphoma in the era of highly active antiretroviral therapy (HAART)
    • DOI 10.1080/10428190400015733
    • Wolf T, Brodt HR, Fichtlscherer S, et al. Changing incidence and prognostic factors of survival in AIDS-related non-Hodgkin's lymphoma in the era of highly active antiretroviral therapy (HAART). Leuk Lymphoma 2005; 46:207-215. (Pubitemid 40185950)
    • (2005) Leukemia and Lymphoma , vol.46 , Issue.2 , pp. 207-215
    • Wolf, T.1    Brodt, H.-R.2    Fichtlscherer, S.3    Mantzsch, K.4    Hoelzer, D.5    Helm, E.B.6    Mitrou, P.S.7    Chow, K.U.8
  • 47
    • 0037093067 scopus 로고    scopus 로고
    • Antitumorigenic effects of HIV protease inhibitor ritonavir: Inhibition of kaposi sarcoma
    • DOI 10.1182/blood.V99.10.3771
    • Pati S, Pelser CB, Dufraine J, et al. Antitumorigenic effects of HIV protease inhibitor ritonavir: inhibition of Kaposi sarcoma. Blood 2002; 99:3771-3779. (Pubitemid 34534550)
    • (2002) Blood , vol.99 , Issue.10 , pp. 3771-3779
    • Pati, S.1    Pelser, C.B.2    Dufraine, J.3    Bryant, J.L.4    Reitz Jr., M.S.5    Weichold, F.F.6
  • 49
    • 0141431026 scopus 로고    scopus 로고
    • Use of HIV protease inhibitors to block Kaposi's sarcoma and tumour growth
    • DOI 10.1016/S1470-2045(03)01192-6, PII S1470204503011926
    • Sgadari C, Monini P, Barillari G, Ensoli B. Use of HIV protease inhibitors to block Kaposi's sarcoma and tumour growth. Lancet Oncol 2003; 4:537-547. (Pubitemid 38351710)
    • (2003) Lancet Oncology , vol.4 , Issue.9 , pp. 537-547
    • Sgadari, C.1    Monini, P.2    Barillari, G.3    Ensoli, B.4
  • 50
    • 5644244886 scopus 로고    scopus 로고
    • HIV-1 protease inhibitor, ritonavir: A potent inhibitor of CYP3A4, enhanced the anticancer effects of docetaxel in androgen-independent prostate cancer cells in vitro and in vivo
    • DOI 10.1158/0008-5472.CAN-03-2677
    • Ikezoe T, Hisatake Y, Takeuchi T, et al. HIV-1 protease inhibitor, ritonavir: a potent inhibitor of CYP3A4, enhanced the anticancer effects of docetaxel in androgen-independent prostate cancer cells in vitro and in vivo. Cancer Res 2004; 64:7426-7431. (Pubitemid 39372084)
    • (2004) Cancer Research , vol.64 , Issue.20 , pp. 7426-7431
    • Ikezoe, T.1    Hisatake, Y.2    Takeuchi, T.3    Ohtsuki, Y.4    Yang, Y.5    Said, J.W.6    Taguchi, H.7    Koeffler, H.P.8
  • 51
    • 0037105651 scopus 로고    scopus 로고
    • The human immunodeficiency virus (HIV)-1 protease inhibitor saquinavir inhibits proteasome function and causes apoptosis and radiosensitization in non-HIV-associated human cancer cells
    • Pajonk F, Himmelsbach J, Riess K, et al. The human immunodeficiency virus (HIV)-1 protease inhibitor saquinavir inhibits proteasome function and causes apoptosis and radiosensitization in non-HIV-associated human cancer cells. Cancer Res 2002; 62:5230-5235. (Pubitemid 35024595)
    • (2002) Cancer Research , vol.62 , Issue.18 , pp. 5230-5235
    • Pajonk, F.1    Himmelsbach, J.2    Riess, K.3    Sommer, A.4    McBride, W.H.5
  • 53
    • 34247265390 scopus 로고    scopus 로고
    • The HIV protease inhibitor nelfinavir downregulates Akt phosphorylation by inhibiting proteasomal activity and inducing the unfolded protein response
    • DOI 10.1593/neo.07124
    • Gupta AK, Li B, Cerniglia GJ, et al. The HIV protease inhibitor nelfinavir downregulates Akt phosphorylation by inhibiting proteasomal activity and inducing the unfolded protein response. Neoplasia 2007; 9:271-278. (Pubitemid 46608294)
    • (2007) Neoplasia , vol.9 , Issue.4 , pp. 271-278
    • Gupta, A.K.1    Li, B.2    Cerniglia, G.J.3    Ahmed, M.S.4    Hahn, S.M.5    Maity, A.6
  • 54
    • 36348961452 scopus 로고    scopus 로고
    • HIV-1 protease inhibitors nelfinavir and atazanavir induce malignant glioma death by triggering endoplasmic reticulum stress
    • DOI 10.1158/0008-5472.CAN-07-0796
    • Pyrko P, Kardosh A, Wang W, et al. HIV-1 protease inhibitors nelfinavir and atazanavir induce malignant glioma death by triggering endoplasmic reticulum stress. Cancer Res 2007; 67:10920-10928. (Pubitemid 350145921)
    • (2007) Cancer Research , vol.67 , Issue.22 , pp. 10920-10928
    • Pyrko, P.1    Kardosh, A.2    Wang, W.3    Xiong, W.4    Schonthal, A.H.5    Chen, T.C.6
  • 55
    • 67849096627 scopus 로고    scopus 로고
    • The HIV protease inhibitor Nelfinavir inhibits human SW872 liposarcoma clonogenicity by inducing apoptosis and is associated with an increase in levels of SREBP-1
    • abstract. abstract 535
    • Valdes F, Chow WA. The HIV protease inhibitor Nelfinavir inhibits human SW872 liposarcoma clonogenicity by inducing apoptosis and is associated with an increase in levels of SREBP-1 [abstract]. In: 95th Annual Meeting of the American Association for Cancer Research; 27-31 March 2004; Orlando, Florida: abstract 535.
    • 95th Annual Meeting of the American Association for Cancer Research; 27-31 March 2004; Orlando, Florida
    • Valdes, F.1    Chow, W.A.2
  • 56
    • 45749106028 scopus 로고    scopus 로고
    • Phase I trial of the human immunodeficiency virus protease inhibitor nelfinavir and chemoradiation for locally advanced pancreatic cancer
    • Brunner TB, Geiger M, Grabenbauer GG, et al. Phase I trial of the human immunodeficiency virus protease inhibitor nelfinavir and chemoradiation for locally advanced pancreatic cancer. J Clin Oncol 2008; 26:2699-2706.
    • (2008) J Clin Oncol , vol.26 , pp. 2699-2706
    • Brunner, T.B.1    Geiger, M.2    Grabenbauer, G.G.3
  • 59
    • 70349532901 scopus 로고    scopus 로고
    • A multicenter, randomized, double-blind, comparative trial of a novel CCR5 antagonist, maraviroc versus efavirenz, both in combination with combivir (zidovudine [ZDV]/lamivudine [3TC]), for the treatment of antiretroviral naive patients infected with R5 HIV 1: Week 48 results of the MERIT study
    • abstract. abstract WESS104
    • Saag M, Ive P, Heera J, et al. A multicenter, randomized, double-blind, comparative trial of a novel CCR5 antagonist, maraviroc versus efavirenz, both in combination with combivir (zidovudine [ZDV]/lamivudine [3TC]), for the treatment of antiretroviral naive patients infected with R5 HIV 1: week 48 results of the MERIT study [abstract]. In: 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention; 22-25 July 2007; Sydney, Australia: abstract WESS104.
    • 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention; 22-25 July 2007; Sydney, Australia
    • Saag, M.1    Ive, P.2    Heera, J.3
  • 61
    • 0032551162 scopus 로고    scopus 로고
    • Spectrum of AIDS-associated malignant disorders
    • Goedert JJ, Cote TR, Virgo P, et al. Spectrum of AIDS-associated malignant disorders. Lancet 1998; 351:1833-1839.
    • (1998) Lancet , vol.351 , pp. 1833-1839
    • Goedert, J.J.1    Cote, T.R.2    Virgo, P.3
  • 62
    • 0032927497 scopus 로고    scopus 로고
    • Risk of cancer in people with AIDS
    • Grulich AE, Wan X, Law MG, et al. Risk of cancer in people with AIDS. AIDS 1999; 13:839-843.
    • (1999) AIDS , vol.13 , pp. 839-843
    • Grulich, A.E.1    Wan, X.2    Law, M.G.3
  • 63
    • 0037165879 scopus 로고    scopus 로고
    • Rates of non-AIDS-defining cancers in people with HIV infection before and after AIDS diagnosis
    • DOI 10.1097/00002030-200205240-00009
    • Grulich AE, Li Y, McDonald A, et al. Rates of non-AIDS-defining cancers in people with HIV infection before and after AIDS diagnosis. AIDS 2002; 16:1155-1161. (Pubitemid 34533854)
    • (2002) AIDS , vol.16 , Issue.8 , pp. 1155-1161
    • Grulich, A.E.1    Li, Y.2    McDonald, A.3    Correll, P.K.L.4    Law, M.G.5    Kaldor, J.M.6
  • 68
    • 67849123628 scopus 로고    scopus 로고
    • Association between CD4 and HIV RNA with non AIDS-related causes of death in the era of combination antiretroviral therapy (cART)
    • abstract. abstract WEPEB019. Using data from Concerted Action on Seroconversion to AIDS and Death in Europe (CASCADE), this is the largest study to date on topic among patients with known duration of HIV infection
    • Marin B, Thiébaut R, Rondeau V, et al. Association between CD4 and HIV RNA with non AIDS-related causes of death in the era of combination antiretroviral therapy (cART) [abstract]. In: 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention; 22-25 July 2007; Sydney, Australia: abstract WEPEB019. Using data from Concerted Action on Seroconversion to AIDS and Death in Europe (CASCADE), this is the largest study to date on topic among patients with known duration of HIV infection.
    • 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention; 22-25 July 2007; Sydney, Australia
    • Marin, B.1    Thiébaut, R.2    Rondeau, V.3
  • 69
    • 42449086328 scopus 로고    scopus 로고
    • CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection
    • DOI 10.1097/QAD.0b013e3282f7cb76, PII 0000203020080423000006
    • Baker JV, Peng G, Rapkin J, et al. CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection. AIDS 2008; 22:841-848. One of few randomized clinical trials to focus on malignancies and provides a comprehensive overview of association between immunodeficiency and fatal malignancies and other fatal non-AIDS conditions. (Pubitemid 351563833)
    • (2008) AIDS , vol.22 , Issue.7 , pp. 841-848
    • Baker, J.V.1    Peng, G.2    Rapkin, J.3    Abrams, D.I.4    Silverberg, M.J.5    MacArthur, R.D.6    Cavert, W.P.7    Henry, W.K.8    Neaton, J.D.9
  • 70
    • 67849093615 scopus 로고    scopus 로고
    • HIV-induced immunodeficiency and risk of fatal AIDS-defining and non-AIDS-defining malignancies: Results fromthe D:A:D study
    • abstract. abstract 84. An excellent description of association of immunodeficiency and risk of fatal malignancies and risk factors for ADMs and NADMs
    • Monforte AD, Abrams D, Pradier C, et al. HIV-induced immunodeficiency and risk of fatal AIDS-defining and non-AIDS-defining malignancies: results fromthe D:A:D study [abstract]. In: 14th Conference on Retroviruses and Opportunistic Infections; 25-28 February 2007; Los Angeles, California: abstract 84. An excellent description of association of immunodeficiency and risk of fatal malignancies and risk factors for ADMs and NADMs.
    • 14th Conference on Retroviruses and Opportunistic Infections; 25-28 February 2007; Los Angeles, California
    • Monforte, A.D.1    Abrams, D.2    Pradier, C.3
  • 71
    • 67849126150 scopus 로고    scopus 로고
    • Trends in incidence of non- AIDS-defining malignancies in HIV-infected vs. noninfected veterans in the HAART era: Impact of immunosuppression
    • abstract. abstract MOPE0243. A large cohort study and one of few studies to include HIV-uninfected persons from same population (i.e., US Veterans)
    • Bedimo R, Dunlap M, McGinnis K, et al. Trends in incidence of non- AIDS-defining malignancies in HIV-infected vs. noninfected veterans in the HAART era: impact of immunosuppression [abstract]. In: 17th International AIDS Conference; 3-8 August 2008; Mexico City, Mexico: abstract MOPE0243. A large cohort study and one of few studies to include HIV-uninfected persons from same population (i.e., US Veterans).
    • 17th International AIDS Conference; 3-8 August 2008; Mexico City, Mexico
    • Bedimo, R.1    Dunlap, M.2    McGinnis, K.3
  • 73
    • 34347323902 scopus 로고    scopus 로고
    • Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: A meta-analysis
    • A large metaanalysis providing novel comparison of NADM risk in two immunosuppressed populations: patients with HIV or AIDS and transplant recipients
    • Grulich AE, van Leeuwen MT, Falster MO, Vajdic CM. Incidence of cancers in people with HIV/AIDS compared with immunosuppressed transplant recipients: a meta-analysis. Lancet 2007; 370:59-67. A large metaanalysis providing novel comparison of NADM risk in two immunosuppressed populations: patients with HIV or AIDS and transplant recipients.
    • (2007) Lancet , vol.370 , pp. 59-67
    • Grulich, A.E.1    Van Leeuwen, M.T.2    Falster, M.O.3    Vajdic, C.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.