-
1
-
-
40949096102
-
-
(a) Bunce, R. A.; Rogers, D.; Nago, T.; Bryant, S. A. J Heterocyclic Chem 2008, 45, 547;
-
(2008)
J Heterocyclic Chem
, vol.45
, pp. 547
-
-
Bunce, R.A.1
Rogers, D.2
Nago, T.3
Bryant, S.A.4
-
2
-
-
40949127021
-
-
(b) Bunce, R. A.; Nago, T.; Sonobe, N.; Slaughter, L. M. J Heterocyclic Chem 2008, 45, 551;
-
(2008)
J Heterocyclic Chem
, vol.45
, pp. 551
-
-
Bunce, R.A.1
Nago, T.2
Sonobe, N.3
Slaughter, L.M.4
-
4
-
-
0001046633
-
-
See for example a
-
See for example (a) Johnson, W. S.; Woroch, E. L.; Buell, B. G. J Am Chem Soc 1949, 71, 1901;
-
(1949)
J Am Chem Soc
, vol.71
, pp. 1901
-
-
Johnson, W.S.1
Woroch, E.L.2
Buell, B.G.3
-
8
-
-
0037078244
-
-
Anderson, K. W.; Tepe, J. J. Tetrahedron 2002, 58, 8475.
-
(b) Anderson, K. W.; Tepe, J. J. Tetrahedron 2002, 58, 8475.
-
-
-
-
10
-
-
27544434859
-
-
Baraznenok, I. L.; Nenaidenko, V. G.; Balenkova, E. S. Chem Heterocyclic Compd 1997, 33, 429.
-
(1997)
Chem Heterocyclic Compd
, vol.33
, pp. 429
-
-
Baraznenok, I.L.1
Nenaidenko, V.G.2
Balenkova, E.S.3
-
11
-
-
67749090628
-
-
Bayburt, E. K.; Daanen, J. F.; Gomtsyan, A. R.; Latshaw, S. P.; Lee, C.-H.; Schmidt, R. G. U.S. Pat. 20080153871 (2008), 45;
-
(a) Bayburt, E. K.; Daanen, J. F.; Gomtsyan, A. R.; Latshaw, S. P.; Lee, C.-H.; Schmidt, R. G. U.S. Pat. 20080153871 (2008), 45;
-
-
-
-
12
-
-
67749109606
-
-
(b) Bayburt, E. K.; Daanen, J. F.; Gomtsyan, A. R.; Latshaw, S. P.; Lee, C.-H.; Schmidt, R. G. Chem Abstr 2008, 149, 104611;
-
(2008)
Chem Abstr
, vol.149
, pp. 104611
-
-
Bayburt, E.K.1
Daanen, J.F.2
Gomtsyan, A.R.3
Latshaw, S.P.4
Lee, C.-H.5
Schmidt, R.G.6
-
13
-
-
67749097318
-
-
Glamkowski, E. J.; Hamer, R. R. L. U.S. Pat. 4,786,644 (1988), 14;
-
(c) Glamkowski, E. J.; Hamer, R. R. L. U.S. Pat. 4,786,644 (1988), 14;
-
-
-
-
15
-
-
0018184031
-
-
Bagolini, C.; de Witt, P.; Pacifici, L.; Ramacci, M. T. J Med Chem 1978, 21, 476.
-
(1978)
J Med Chem
, vol.21
, pp. 476
-
-
Bagolini, C.1
de Witt, P.2
Pacifici, L.3
Ramacci, M.T.4
-
16
-
-
67749138756
-
-
Hom, R.; Tucker, J.; Varghese, J.; Shah, N. World Patent WO 2005095326 (2005), 365;
-
(a) Hom, R.; Tucker, J.; Varghese, J.; Shah, N. World Patent WO 2005095326 (2005), 365;
-
-
-
-
17
-
-
67749107773
-
-
(b) Hom, R.; Tucker, J.; Varghese, J.; Shah, N. Chem Abstr 2005, 143, 386930.
-
(2005)
Chem Abstr
, vol.143
, pp. 386930
-
-
Hom, R.1
Tucker, J.2
Varghese, J.3
Shah, N.4
-
18
-
-
67749107619
-
-
Varghese, J.; Maillard, M.; Fang, L; Tucker, J.; Brogley, L.; Aquino, J.; Bowers, S.; Probst, G.; Tung, J. World Patent WO 2005087714 (1995), 428;
-
(c) Varghese, J.; Maillard, M.; Fang, L; Tucker, J.; Brogley, L.; Aquino, J.; Bowers, S.; Probst, G.; Tung, J. World Patent WO 2005087714 (1995), 428;
-
-
-
-
19
-
-
67749103325
-
-
VargheseJ.; Maillard, M.; Fang, L; Tucker, J.; Brogley, L.; Aquino, J.; Bowers, S.; Probst, G.; Tung, J. Chem Abstr 2005, 143, 326226.
-
(d) VargheseJ.; Maillard, M.; Fang, L; Tucker, J.; Brogley, L.; Aquino, J.; Bowers, S.; Probst, G.; Tung, J. Chem Abstr 2005, 143, 326226.
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-
-
-
20
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67749130437
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-
These compounds are also currently being evaluated for the treatment of: (a) Central nervous system disorders: Galley, G, Groebke Zbinden, K. G, Norcross, R, Stalder, H. World Patent WO 2007085558 2007, 85;
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These compounds are also currently being evaluated for the treatment of: (a) Central nervous system disorders: Galley, G.; Groebke Zbinden, K. G.; Norcross, R.; Stalder, H. World Patent WO 2007085558 (2007), 85;
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-
-
-
21
-
-
67749139275
-
-
(b) Galley, G.; Groebke Zbinden, K. G.; Norcross, R.; Stalder, H. Chem Abstr 2007, 147, 841292;
-
(2007)
Chem Abstr
, vol.147
, pp. 841292
-
-
Galley, G.1
Groebke Zbinden, K.G.2
Norcross, R.3
Stalder, H.4
-
22
-
-
67749085726
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Potassium channel blockers: Gerlach, U, Brendel, J, Lang, H. J, Weidmann, K. Eur. Pat. EP 857,724 1998, 23;
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(c) Potassium channel blockers: Gerlach, U.; Brendel, J.; Lang, H. J.; Weidmann, K. Eur. Pat. EP 857,724 (1998), 23;
-
-
-
-
23
-
-
67749128864
-
-
(d) Gerlach, U.; Brendel, J.; Lang, H. J.; Weidmann, K. Chem Abstr 1998, 129, 175447.
-
(1998)
Chem Abstr
, vol.129
, pp. 175447
-
-
Gerlach, U.1
Brendel, J.2
Lang, H.J.3
Weidmann, K.4
-
24
-
-
67749119474
-
-
Cancer: Vicker, N, Day, J. M, Bailey, H. V, Heaton, W, Gonzalez, A. M. R, Sharland, C. M, Reed, M. J, Purohit, A, Potter, B. V. L. World Patent 2007003934 2007, 266;
-
(e) Cancer: Vicker, N.; Day, J. M.; Bailey, H. V.; Heaton, W.; Gonzalez, A. M. R.; Sharland, C. M.; Reed, M. J.; Purohit, A.; Potter, B. V. L. World Patent 2007003934 (2007), 266;
-
-
-
-
25
-
-
67749138755
-
-
(f) Vicker, N.; Day, J. M.; Bailey, H. V.; Heaton, W.; Gonzalez, A. M. R.; Sharland, C. M.; Reed, M. J.; Purohit, A.; Potter, B. V. L. Chem Abstr 2007, 146, 142281.
-
(2007)
Chem Abstr
, vol.146
, pp. 142281
-
-
Vicker, N.1
Day, J.M.2
Bailey, H.V.3
Heaton, W.4
Gonzalez, A.M.R.5
Sharland, C.M.6
Reed, M.J.7
Purohit, A.8
Potter, B.V.L.9
-
27
-
-
0027394922
-
-
Shen, W.; Coburn, C. A.; Bornmann, W. G.; Danishefsky, S. J. J Org Chem 1993, 58, 611.
-
Shen, W.; Coburn, C. A.; Bornmann, W. G.; Danishefsky, S. J. J Org Chem 1993, 58, 611.
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-
-
-
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13C nmr spectra were obtained using ACD HNMR and CNMR software from Advanced Chemistry Development, Inc. Toronto, Canada, 2007.
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13C nmr spectra were obtained using ACD HNMR and CNMR software from Advanced Chemistry Development, Inc. Toronto, Canada, 2007.
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-
-
-
29
-
-
0002714675
-
-
Still, W. C.; Kahn, M.; Mitra, A. J Org Chem 1978, 43, 2923.
-
(1978)
J Org Chem
, vol.43
, pp. 2923
-
-
Still, W.C.1
Kahn, M.2
Mitra, A.3
-
30
-
-
0343462158
-
-
Wiley: New York, NY
-
Eisenbraun, E. J. Organic Syntheses; Wiley: New York, NY, 1973; Vol. V, pp 310-314.
-
(1973)
Organic Syntheses
, vol.5
, pp. 310-314
-
-
Eisenbraun, E.J.1
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31
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This is a known compound, but it is reported with only a boiling point 175-177°C, 0.2 mmHg, see Atwal, M. S, Bauer, L, Dixit, S. N, Gearien, J. E, Morris, R. W. J Med Chem 1965, 8, 566. Reference 8a also reports this compound without a melting point
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This is a known compound, but it is reported with only a boiling point (175-177°C, 0.2 mmHg), see Atwal, M. S.; Bauer, L.; Dixit, S. N.; Gearien, J. E.; Morris, R. W. J Med Chem 1965, 8, 566. Reference 8a also reports this compound without a melting point.
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