Plasma fibrinolysis is related to the degree of organ dysfunction but not to the concentration of von Willebrand factor in critically ill patients

Thrombosis Journal

Volumn 7, Issue , 2009, Pages

  Boudjeltia, Karim Zouaoui ^a   Ollieuz, Sandra ^b   Piagnerelli, Michael ^c   Biston, Patrick ^b   Cauchie, Philippe ^a   Vincent, Jean Louis ^c   Brohee, Dany ^a   Vanhaeverbeek, Michel ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b Centre Hospitalier Universitaire de Charleroi   (Belgium)

^c ERASME HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; C REACTIVE PROTEIN; CREATININE; FIBRINOGEN; VON WILLEBRAND FACTOR;

ADULT; ARTICLE; BILIRUBIN BLOOD LEVEL; BLOOD CLOTTING TIME; BLOOD SAMPLING; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; CRITICALLY ILL PATIENT; DISEASE SEVERITY; ENDOCARDITIS; ENDOTHELIAL DYSFUNCTION; EUGLOBULIN LYSIS TEST; FIBRINOLYSIS; HEART FAILURE; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HUMAN; INTENSIVE CARE UNIT; LEUKOCYTE COUNT; MEDIASTINITIS; MORTALITY; MULTIPLE ORGAN FAILURE; PERITONITIS; PNEUMONIA; PROGNOSIS; PROTEIN BLOOD LEVEL; PROTHROMBIN TIME; SEPSIS; SKIN INFECTION; THROMBOCYTE COUNT; UREA BLOOD LEVEL; URINARY TRACT INFECTION;

EID: 67749142101     PISSN: None     EISSN: 14779560     Source Type: Journal    
DOI: 10.1186/1477-9560-7-10     Document Type: Article

References (32)

1. Aird WC The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome Blood 2003, 101:3765-3777 10.1182/ blood-2002-06-1887 12543869
2. Idell S Coagulation, fibrinolysis, and fibrin deposition in acute lung injury Crit Care Med 2003, 31:S213-S220 10.1097/ 01.CCM.0000057846.21303.AB 12682443
3. Lobo SM Lobo FR Bota DP Lopes-Ferreira F Soliman HM Melot C Vincent JL C-reactive protein levels correlate with mortality and organ failure in critically ill patients Chest 2003, 123:2043-2049 10.1378/ chest.123.6.2043 12796187
4. Devaraj S Xu DY Jialal I C-reactive protein increases plasminogen activator inhibitor-1 expression and activity in human aortic endothelial cells: Implications for the metabolic syndrome and atherothrombosis Circulation 2003, 107:398-404 10.1161/ 01.CIR.0000052617.91920.FD 12551862
5. Bisoendial RJ Kasteleuin JJ Levels JHM Zwaginga JJ Bogaard Van den B Reitsma PH Meijers CM Hartman D Levi M Stroes ESG Activation of inflammation and Coagulation after infusion of C-reactive protein in humans Circ Res 2005, 96:714-716 10.1161/01.RES.0000163015.67711.AB 15774855
6. Zouaoui Boudjeltia K Piagnerelli M Brohee D Guillaume M Cauchie P Vincent JL Remacle C Boukaert Y Vanhaeverbeek M Relationship between CRP and hypofibrinolysis: Is this a possible mechanism to explain the association between CRP and outcome in critically ill patients? Thromb J 2004, 2:7 524363 15456513 10.1186/1477-9560-2-7
7. Blann AD Plasma von Willebrand factor, thrombosis and the endothelium:tHe first 30 years Thromb Haemost 2006, 95:49-55 16543961
8. Vincent JL Moreno R Takala J Willatts S De Mendonca A Bruining H Reinhart CK Suter PM Thijs LG The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine Intensive Care Med 1996, 22:707-10 10.1007/ BF01709751 8844239
9. Le Gall JR Lemeshow S Saulnier F A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study JAMA 1993, 270:2957-2963 10.1001/jama.270.24.2957 8254858
10. Levy MM Fink MP Marshall JC Abraham E Angus D Cook D Cohen J Opal SM Vincent JL Ramsay G SCCM/ESICM/ACCP/ATS/SIS international sepsis definitions conference Crit Care Med 2003, 31:1250-1256 10.1097/ 01.CCM.0000050454.01978.3B 12682500
11. Zouaoui Boudjeltia K Cauchie P Remacle C Guillaume M Brohee D Hubert JL Vanhaeverbeek M A new device for measurement of fibrin clot lysis: application to the euglobulin clot lysis time BMC Biotechnol 2002, 2:8 113256 11985782 10.1186/1472-6750-2-8
12. Okabayashi K Wada H Ohta S Shiku H Nobori T Maruyama K Hemostatic markers and the sepsis-related organ failure assessment score in patients with disseminated intravascular coagulation in an intensive care unit Am J Hematol 2004, 76:225-229 10.1002/ajh.20089 15224356
13. Kinasewitz GT Yan SB Basson B Comp P Russell JA Cariou A Um SL Utterback B Laterre PF Dhainaut JF PROWESS Sepsis Study Group Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569] Crit Care 2004, 8:R82-90 420030 15025782 10.1186/cc2459
14. Dhainaut JF Shorr AF Macias WL Kollef MJ Levi M Reinhart K Nelson DR Dynamic evolution of coagulopathy in the first day of severe sepsis: relationship with mortality and organ failure Crit Care Med 2005, 33:341-348 10.1097/01.CCM.0000153520.31562.48 15699837
15. Cheng B Xie G Yao S Wu X Guo Q Gu M Fang Q Xu Q Wang D Jin Y Yuan S Wang J Du Z Sun Y Fang X Epidemiology of severe sepsis in critically ill surgical patients in ten university hospitals in China Crit Care Med 2007, 35:2538-2546 10.1097/01.CCM.0000284492.30800.00 17828034
16. Rivera-Fernández R Nap R Vázquez-Mata G Reis Miranda D Analysis of physiologic alterations in intensive care unit patients and their relationship with mortality J Crit Care 2007, 22:120-128 10.1016/ j.jcrc.2006.09.005 17548023
17. Gross PL Aird WC The endothelium and thrombosis Semin Thromb Hemost 2000, 26:463-478 10.1055/s-2000-13202 11129402
18. Tomiyama H Kumura Y Mitsuhashi H Kinouchi T Yoshida H Kushiro T Doba N Relationship between endothelial function and fibrinolysis in early hypertension Hypertension 1998, 31:321-327 9453323
19. Poderos P Endothelial dysfunction in the pathogenesis of atherosclerosis Int Angiol 2002, 21:109-116 12110769
20. Cerinic MM Valentini G Sorano GG D'angelo S Cuomo G Fenu L Generini S Cinotti S Morfini M Pignono A Guiducci S Del Rosso A Kaflin R Das D Marongiu F Blood coagulation, fibrinolysis and markers of endothelial dysfunction in systemic sclerosis Semin Arthritis Rheum 2003, 32:285-295 10.1053/sarh.2002.50011 12701039
21. Schleef RR Bridwell CR Biochemical changes in endothelial cell monolayers induced by fibrin deposition in vitro Arteriosclerosis 1984, 4:14-20 6691841
22. Weimar B Delvos U The mechanism of fibrin-induced disorganization of cultured human endothelial cell monolayers Arteriosclerosis 1986, 6:139-145 3513750
23. Qi J Kerutzer DL Fibrin regulation of interleukin-8 gene expression in human vascular endothelial cells Blood 1997, 90:3595-3602 9345043
24. Mavrommatis AC Theodoridis T Economou M Kotanidou A El Ali M Christopoulou-Kokkinou V Zakynthinos SG Activation of the fibrinolytic system and utilization of the coagulation inhibitors in sepsis: comparison with severe sepsis and septic shock Intensive Care Med 2001, 27:1853-1859 10.1007/s00134-001-1139-8 11797019
25. van Genderen PJ Prins FJ Lucas IS van de Moesdijk D van Cliet H van Strik R Michiels JJ Decreased half-life time of plasma von Willebrand factor collagen binding activity in essential thrombocythaemia: normalization after cytoreduction of the increased platelet count Br J Haematol 1997, 99:832-836 10.1046/j.1365-2141.1997.4823285.x 9432029
26. Zouaoui Boudjeltia K Guillaume M Henuzet C Delree P Cauchie P Remacle C Ducobu J Vanhaeverbeek M Brohee D Fibrinolysis and cardiovascular risk factors: Association with fibrinogen lipids, and monocyte count Eur J Intern Med 2006, 17:102-108 10.1016/j.ejim.2005.11.002 16490686
27. Koj A Gauldie J Regoeczi E Sauder DN Sweeney GD The acute-phase response of cultured rat hepatocytes. System characterization and the effect of human cytokines Biochem J 1984, 224:505-514 1144459 6083778
28. Seki T Gelehrter TD Interleukin-1 induction of type-1 plasminogen activator inhibitor (PAI-1) gene expression in the mouse hepatocyte line, AML 12 J Cell Physiol 1996, 168:648-656 10.1002/ (SICI)1097-4652(199609)168:3<648::AID-JCP17>3.0.CO;2-V 8816919
29. Chong AY Blann AD Lip GYH Assessment of endothelial damage and dysfunction observations in relation to heart failure QJM. 2003, 96(4):253-267 10.1093/qjmed/hcg037 12651970
30. Reinhart K Bayer O Brunkhorst F Meisner M Markers of endothelial damage dysfunction and sepsi Crit Care Med 2002, 30:S302-S312 10.1097/ 00003246-200205001-00021 12004252
31. Ware LB Eisneir MD Thompson BT Parsons PE Matthay MA Significance of von Willebrand factor in septic and nonseptic patients with acute lung injury Am J Respir Crit Care Med 2004, 170:766-772 10.1164/ rccm.200310-1434OC 15201135
32. Kayal S Jaïs JP Aguini N Chaudiere J Labrousse J Elevated circulating E-selectin, intercellular adhesion molecule-1 and von willebrand factor in patients with severe infection Am J Respir Crit Care Med. 1998, 157(3 Pt 1):776-784 9517590