Expression of tight junction protein claudin-4 in Basal-Like breast carcinomas

Pathology and Oncology Research

Volumn 15, Issue 1, 2009, Pages 59-64

  Kulka, Janina ^a   Szász, Attila Marcell ^a   Németh, Zsuzsanna ^a   Madaras, Lilla ^a   Schaff, Zsuzsa ^a   Molnár, István Arthur ^a   Tokés, Anna Mária ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Basal like; Breast carcinoma; Claudin 4; Immunohistochemistry; Tissue microarray

Indexed keywords

CLAUDIN 4; CYTOKERATIN 5; CYTOKERATIN 6; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; KI 67 ANTIGEN; PROGESTERONE RECEPTOR; PROTEIN P53;

ADULT; ARTICLE; BREAST CARCINOMA; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PROTEIN EXPRESSION;

BREAST NEOPLASMS; CARCINOMA, ADENOSQUAMOUS; CARCINOMA, BASAL CELL; CARCINOMA, LOBULAR; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU HYBRIDIZATION, FLUORESCENCE; MEMBRANE PROTEINS; MIDDLE AGED; PROGNOSIS; RECEPTOR, ERBB-2; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; TISSUE ARRAY ANALYSIS;

EID: 67749093433     PISSN: 12194956     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12253-008-9089-x     Document Type: Article

References (18)

1. CM Perou T Sorlie MB Eisen 2000 Molecular portraits of human breast tumours Nature 406 747 752
2. LG Fulford JS Reis-Filho K Ryder 2007 Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival Breast Cancer Res 9 R4
3. S Banerjee JS Reis-Filho S Ashley 2006 Basal-like breast carcinomas: clinical outcome and response to chemotherapy J Clin Pathol 59 729 735
4. Z Hu C Fan DS Oh 2006 The molecular portraits of breast tumors are conserved across microarray platforms BMC Genomics 7 96
5. T Sorlie 2007 Molecular classification of breast tumors: toward improved diagnostics and treatments Methods Mol Biol 360 91 114
6. L Da Silva C Clarke SR Lakhani 2007 Demystifying basal-like breast carcinomas J Clin Pathol 60 1328 1332
7. BB Bryan SJ Schnitt LC Collins 2006 Ductal carcinoma in situ with basal-like phenotype: a possible precursor to invasive basal-like breast cancer Mod Path 19 617 621
8. H Buerger F Otterbach R Simon 1999 Different genetic pathways in the evolution of invasive breast cancer are associated with distinct morphological subtypes J Path 189 521 526
9. M Kondoh 2006 Claudin as a novel target for drug delivery system Yakugaku Zasshi 126 711 721
10. AM Tokes J Kulka S Paku 2005 The expression of five different claudins in invasive breast carcinomas: comparison of pT1pN1 and pT1pN0 tumors Pathol Res Pract 201 537 544
11. AM Tokes J Kulka S Paku 2005 Claudin-1, -3 and -4 proteins and mRNA expression in benign and malignant breast lesions: a research study Breast Cancer Res 7 R296 R305
12. M Furuse K Fujita T Hiiragi 1998 Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin J Cell Biol 141 1539 1550
13. G Sobel C Paska I Szabo 2005 Increased expression of claudins in cervical squamous intraepithelial neoplasia and invasive carcinoma Human Pathol 36 162 169
14. G Sobel J Nemeth A Kiss 2006 Claudin 1 differentiates endometrioid and serous papillary endometrial adenocarcinoma Gynecol Oncol 103 591 598
15. P Michl C Barth M Buchholz 2003 Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer Cancer Res 63 6265 6271
16. P Michl M Buchholz M Rolke 2001 Claudin-4: a new target for pancreatic cancer treatment using Clostridium perfringens enterotoxin Gastroenterology 121 678 684
17. S Garcia JP Dales E Charafe-Jauffret 2007 Poor prognosis in breast carcinomas correlates with increased expression of targetable CD146 and c-Met and with proteomic basal-like phenotype Human Pathol 38 830 841
18. CA Livasy G Karaca R Nanda 2006 Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma Mod Path 19 264 271