Reducing the Risk of Xerostomia and Mandibular Osteoradionecrosis: The Potential Benefits of Intensity Modulated Radiotherapy in Advanced Oral Cavity Carcinoma

Medical Dosimetry

Volumn 34, Issue 3, 2009, Pages 217-224

  Ahmed, Merina ^a   Hansen, Vibeke N ^a   Harrington, Kevin J ^a,b   Nutting, Christopher M ^a  

^a ROYAL MARSDEN HOSPITAL   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Intensity modulated radiotherapy; Mandible; Oral cancer

Indexed keywords

ADVANCED CANCER; ARTICLE; BONE NECROSIS; BRAIN STEM; CANCER GRADING; CANCER RADIOTHERAPY; CANCER STAGING; CLINICAL ARTICLE; COMPUTER ASSISTED RADIOTHERAPY; EXTERNAL BEAM RADIOTHERAPY; HISTOGRAM; HUMAN; INCIDENCE; INTENSITY MODULATED RADIATION THERAPY; MANDIBLE; MANDIBLE RESECTION; MOUTH CARCINOMA; PAROTID GLAND; PRIORITY JOURNAL; RADIATION DOSE DISTRIBUTION; SALIVARY GLAND; SPINAL CORD; SQUAMOUS CELL CARCINOMA; XEROSTOMIA;

FEASIBILITY STUDIES; HUMANS; MANDIBULAR DISEASES; MOUTH NEOPLASMS; OSTEORADIONECROSIS; RADIATION INJURIES; RADIATION PROTECTION; RADIOMETRY; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, CONFORMAL; RISK FACTORS; XEROSTOMIA;

EID: 67651238724     PISSN: 09583947     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.meddos.2008.08.008     Document Type: Article

References (26)

1. Kademani D., Bell R.B., Bagheri S., et al. Progonostic factors in intraoral squamous cell carcinoma: The influence of histologic grade. J. Oral Maxillofac. Surg 63 (2005) 1599-1605
2. Woolgar J.A., and Scott J. Prediction of cervical lymph node metastasis in squamous cell carcinoma of the tongue/floor of mouth. Head Neck 17 (1995) 463-472
3. Saarilahti M., Kouri J., Collan T., et al. Intensity modulated radiotherapy for head and neck cancer: Evidence for preserved salivary gland function. Radiother. Oncol 74 (2005) 251-258
4. Chao K.S. Protection of salivary function by intensity-modulated radiation therapy in patients with head and neck cancer. Semin. Radiat. Oncol 12 Suppl 1 (2002) 20-25
5. Eisbruch A., Hyungjin M.K., and Terrel J.E. Xerostomia and its predictors following parotid-sparing irradiation for head and neck cancer. Int. J. Radiat. Oncol. Biol. Phys 50 (2001) 695-704
6. Lin A., Kim H.M., Terrell J.E., et al. Quality of life after parotid-sparing IMRT for head and neck cancer-a prospective longitudinal study. Int. J. Radiat. Oncol. Biol. Phys 57 (2003) 61-70
7. Store G., and Boysen M. Mandibular ostoeradionecrosis: Clinical behaviour and diagnostic aspects. Clin. Otolaryngol 25 (2000) 378-384
8. Reuther T., Schuster U., Mende A., et al. Osteoradionecrosis of the jaws as a side effect of radiotherapy of head and neck tumour patients-a report of a 30-year retrospective review. Int. J. Maxillofac. Surg 32 (2003) 289-295
9. ICRU 50. Prescribing, Recording and Reporting Photon Beam Therapy (1993), International Commission on Radiation Units and Measurement, Bethesda, MD
10. ICRU 62. Prescribing, Recording and Reporting Photon Beam Therapy (Supplement to ICRU 50) (1999), International Commission on Radiation Units and Measurement, Bethesda, MD
11. Gregoire V., Levendag P., Ang K.K., Bernier J., et al. CT-based delineation of lymph node levels and related CTVs in the node negative neck: DAHANCA, EORTC, GORTEC, NCIC, RTOG consensus guidelines. Radiother. Oncol 69 (2003) 227-236
12. Humphreys M., Guerro Urbano M.T., Mubata C., et al. Assessment of a customised immobilisation system for head and neck IMRT using electronic portal imaging. Radiother. Oncol 77 (2005) 39-44 Epub 2005 Sep 8, 2005
13. Claus F., Duthoy W., Boterberg T., et al. Intensity modulated radiation therapy for oropharyngeal and oral cavity tumors: Clinical use and experience. Oral Oncol 38 (2002) 597-604
14. Eisbruch A., Randall K.T.H., Hyungjin M.K., et al. Dose volume and function relationships in parotid salivary glands following conformal and intensity-modulated irradiation of head and neck cancer. Int. J. Radiat. Oncol. Biol. Phys 45 (1999) 577-587
15. Chao K.S., Ozygit G., Tran B.N., et al. Patterns of failure in patients receiving definitive and post-operative IMRT for head and neck cancer. Int. J. Radiat. Oncol. Biol. Phys 55 (2003) 312-321
16. Lapeyre M., Henrot P., Alfonsi M., et al. Propositions for the selction and the delineation of peri-tumoural microscopic diseases volumes in the oralcavity and oropharyngeal cancers (lymph nodes excluded). Cancer Radiotherapie 9 (2005) 261-270
17. Bras J., de Jonge H.K., and van Merkesteyn J.P. Osteoradionecrosis of the mandible: Pathogenesis. Am. J. Otolaryngol 11 (1990) 244-250
18. Vissink A., Jansma J., Spijkervet F.K.L., et al. Oral sequelae of head and neck radiotherapy. Crit. Rev. Oral. Biol. Med 14 (2003) 199-212
19. Studer G., Gratz K.W., and Glanzmann C. Osteoradionecrosis of the mandibula in patients treated with different fractionations. Strahlenther. Onkol 180 (2004) 233-240
20. Marx R.E., and Johnson R.P. Studies in the radiobiology of osteoradionecrosis and their clinical significance. Oral Surg. Oral Med. Oral Pathol 64 (1987) 379-390
21. Glanzmann C., and Gratz K.W. Radionecrosis of the mandible: A retrospective analysis of the incidence and risk factors. Radiother. Oncol 36 (1995) 94-100
22. Curi M.M., and Dib L.L. Osteoradionecrosis of the jaws: A retrospective study of the background factors and treatment in 104 cases. J. Oral Maxillofac. Surg 55 (1997) 540-544 discussion 545-6
23. Eisbruch A., Harris J., Garden A., et al. Phase II multi-institutional study of IMRT for oropharyngeal cancer (RTOG 00-22): Early results (abstr. 79). Int. J. Radiat. Oncol. Biol. Phys 66 Suppl (2006) 30
24. Ben-David M.A., Diamante M., Radawaski J.D., et al. Lack of osteoradionecrosis of the mandible after intensity-modulated radiotherapy for head-and neck cancer: Likely contributions of both dental care and improved dose distributions. Int. J. Radiat. Oncol. Biol. Phys 68 (2007) 396-402
25. Studer G., Studer S.P., Zwahlen R.A., et al. Osteoradionecrosis of the mandible minimized risk profile following intensity-modulated radiation therapy (IMRT). Strahlenther. Onkol 182 (2006) 283-288
26. Nutting C.M., Normile P.S., Bedford J., et al. A systematic study of techniques for elective cervical nodal irradiation with anterior or opposed beams. Radiother. Oncol 69 (2003) 43-51