Airway chemosensitive receptors in vagus nerve perform neuro-immune interaction for lung-brain communication

Advances in Experimental Medicine and Biology

Volumn 648, Issue , 2009, Pages 421-426

  Li, H F ^a   Yu, J ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Pro inflammatory cytokines; Reflex; Sensory neuron; Sensory receptors; TNF alpha; Visceral afferents

Indexed keywords

INTERLEUKIN 1BETA; NEUTRALIZING ANTIBODY; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; CYTOKINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; BIOSENSOR; C FIBER RECEPTOR; CHEMOSENSITIVITY; CONFERENCE PAPER; CONTROLLED STUDY; EVOKED RESPONSE; HIGH THRESHOLD A DELTA RECEPTOR; INNATE IMMUNITY; LUNG RECEPTOR; NERVE FUNCTION; NEUROIMMUNOLOGY; NOCICEPTIVE RECEPTOR; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RABBIT; RECEPTIVE FIELD; SENSORY NERVE CONDUCTION; VAGUS NERVE STIMULATION; VAGUS REFLEX; ANIMAL; ARTICLE; BRAIN; IMMUNOLOGY; IMMUNOMODULATION; INNERVATION; LUNG; METABOLISM; PHYSIOLOGY; REFLEX; VAGUS NERVE;

ORYCTOLAGUS CUNICULUS;

ANIMALS; BRAIN; CYTOKINES; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; LUNG; NEUROIMMUNOMODULATION; NOCICEPTORS; RABBITS; REFLEX; VAGUS NERVE;

EID: 67651236669     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-90-481-2259-2_48     Document Type: Conference Paper

References (20)

1. Belvisi, M. G. (2003) Sensory nerves and airway inflammation: role of A delta and C-fibres 1. Pulm Pharmacol Ther, 16, 1-7. (Pubitemid 36349076)
2. Coleridge, H. M. & Coleridge, J. C. G. (1994) Pulmonary reflexes: neural mechanisms of pulmonary defense. Annu Rev Physiol, 56, 69-91. (Pubitemid 24111854)
3. Coleridge, J. C. G. & Coleridge, H. M. (1984) Afferent vagal C fibre innervation of the lungs and airways and its functional significance. Rev Physiol Biochem Pharmacol, 99, 1-110.
4. Czeschik, J. C., Hagenacker, T., Schafers, M. & Busselberg, D. (2008) TNF-alpha differentially modulates ion channels of nociceptive neurons. Neurosci Lett, 434, 293-298.
5. Goehler, L. E., Gaykema, R. P., Hansen, M. K., Anderson, K., Maier, S. F. & Watkins, L. R. (2000) Vagal immune-to-brain communication: a visceral chemosensory pathway. Auton Neurosci, 85, 49-59.
6. Ishitsuka, Y., Moriuchi, H., Hatamoto, K., Yang, C., Takase, J., Golbidi, S., Irikura, M. & Irie, T. (2004) Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs. J Pharm Pharmacol, 56, 513-520. (Pubitemid 38455617)
7. Jin, X. & Gereau, R. W. (2006) Acute p38-mediated modulation of tetrodotoxin-resistant sodium channels in mouse sensory neurons by tumor necrosis factor-alpha. J Neurosci, 26, 246-255. (Pubitemid 43089538)
8. Lai, C. J., Ho, C. Y. & Kou, Y. R. (2002) Activation of lung vagal sensory receptors by circulatory endotoxin in rats. Life Sci, 70, 2125-2138. (Pubitemid 34219463)
9. Lee, L. Y. & Pisarri, T. E. (2001) Afferent properties and reflex functions of bronchopulmonary C-fibers. Respir Physiol, 125, 47-65. (Pubitemid 32185772)
10. Lin, S., Walker, J., Xu, L., Gozal, D. & Yu, J. (2007) Respiratory: Behaviours of pulmonary sensory receptors during development of acute lung injury in the rabbit. Exp Physiol, 92, 749-755. (Pubitemid 47024926)
11. Martin, T. R. (1999) Lung cytokines and ARDS: Roger S. Mitchell Lecture. Chest, 116, 2S-8S.
12. Morrison, D. C. & Ryan, J. L. (1987) Endotoxins and disease mechanisms. Annu Rev Med, 38, 417-432.
13. Otmishi, P., Gordon, J., El-Oshar, S., Li, H., Guardiola, J., Saad, M., Proctor, M. & Yu, J. (2008) Neuroimmune interaction in inflammatory diseases. Clin Med: Circ, Respir and Pulm Med, 2, 35-44.
14. Pavlov, V. A. & Tracey, K. J. (2006) Controlling inflammation: the cholinergic anti-inflammatory pathway. Biochem Soc Trans, 34, 1037-1040. (Pubitemid 46768984)
15. Pollock, J., McFarlane, S. M., Connell, M. C., Zehavi, U., Vandenabeele, P., MacEwan, D. J. & Scott, R. H. (2002) TNF-alpha receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurones. Neuropharmacology, 42, 93-106. (Pubitemid 34062825)
16. Tracey, K. J. (2002) The inflammatory reflex. Nature, 420, 853-859. (Pubitemid 36019638)
17. Undem, B. J. & Carr, M. J. (2001) Pharmacology of airway afferent nerve activity. Respir Res, 2, 234-244. (Pubitemid 34187931)
18. Yu, J. Airway receptors and their reflex function. Springer. 2008. Adv Exp Med Biol. This volume
19. Yu, J. (2005) Airway mechanosensors. Respir Physiol Neurobiol, 148, 217-243. (Pubitemid 41242802)
20. Yu, J., Lin, S., Zhang, J., Otmishi, P. & Guardiola, J. J. (2007) Airway nociceptors activated by pro-inflammatory cytokines. Respir Physiol Neurobiol, 156, 116-119.