Purification of drugs from biological fluids by counter-current chromatography

Journal of Chromatography A

Volumn 1216, Issue 34, 2009, Pages 6162-6169

  Hochlowski, Jill E ^a   Pan, Jeffrey Y ^a   Searle, Philip A ^a   Buck, Wayne R ^a   Spanton, Stephen G ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Bile; Counter current chromatography; Drugs; Metabolites; Pharmaceutical discovery; Serum

Indexed keywords

BILE; COUNTER-CURRENT CHROMATOGRAPHY; DRUGS; PHARMACEUTICAL DISCOVERY; SERUM;

BIOMOLECULES; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METABOLITES;

BODY FLUIDS;

CAMPTOTHECIN; COTININE; FEXOFENADINE; GENISTEIN; NICOTINE; TAUROCHOLIC ACID; TERFENADINE;

ARTICLE; BILE LEVEL; BODY FLUID; CONTROLLED STUDY; COUNTER CURRENT CHROMATOGRAPHY; DOG; DRUG DETERMINATION; DRUG ISOLATION; DRUG METABOLISM; DRUG RESEARCH; DRUG STRUCTURE; EX VIVO STUDY; HUMAN; ION MONITORING; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ANALYTIC SAMPLE PREPARATION METHODS; ANIMALS; BILE; BLOOD CHEMICAL ANALYSIS; BODY FLUIDS; COUNTERCURRENT DISTRIBUTION; DOGS; HUMANS; MASS SPECTROMETRY; PHARMACEUTICAL PREPARATIONS; SOLVENTS;

EID: 67651233815     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.06.068     Document Type: Article

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