메뉴 건너뛰기




Volumn 116, Issue 8, 2009, Pages 1017-1027

Short- and long-term consequences of prenatal exposure to the cannabinoid agonist WIN55,212-2 on rat glutamate transmission and cognitive functions

Author keywords

Basal and K+ evoked glutamate levels; LTP; MAP2 immunoreactivity; Maternal marijuana consumption; Passive avoidance and emotional reactivity

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABIS; GLUTAMIC ACID;

EID: 67651232563     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-009-0230-0     Document Type: Conference Paper
Times cited : (30)

References (70)
  • 1
    • 0032926695 scopus 로고    scopus 로고
    • The effects of cannabinoids on the brain
    • A Ameri 1999 The effects of cannabinoids on the brain Prog Neurobiol 58 315 348
    • (1999) Prog Neurobiol , vol.58 , pp. 315-348
    • Ameri, A.1
  • 2
    • 0038383775 scopus 로고    scopus 로고
    • Four-dimensional migratory coordinates of GABAergic interneurons in the developing mouse cortex
    • ESBC Ang TF Haydar V Gluncic P Rakic 2003 Four-dimensional migratory coordinates of GABAergic interneurons in the developing mouse cortex J Neurosci 23 5805 5815
    • (2003) J Neurosci , vol.23 , pp. 5805-5815
    • Esbc, A.1    Haydar, T.F.2    Gluncic, V.3    Rakic, P.4
  • 3
    • 10744225830 scopus 로고    scopus 로고
    • Long-term effects on cortical glutamate release induced by prenatal exposure to the cannabinoid receptor agonist (R)-(+)-[2, 3-dihydro-5-methyl-3- (4-morpholinyl-methyl)pyrrolo[1, 2, 3-de]-1, 4-benzoxazin-6-yl]-1- naphthalenylmethanone: An in vivo microdialysis study in the awake rat
    • T Antonelli S Tanganelli MC Tomasini S Finetti L Trabace L Steardo V Sabino MR Carratu V Cuomo L Ferraro 2004 Long-term effects on cortical glutamate release induced by prenatal exposure to the cannabinoid receptor agonist (R)-(+)-[2, 3-dihydro-5-methyl-3-(4-morpholinyl-methyl)pyrrolo[1, 2, 3-de]-1, 4-benzoxazin-6-yl]-1-naphthalenylmethanone: an in vivo microdialysis study in the awake rat Neuroscience 124 367 375
    • (2004) Neuroscience , vol.124 , pp. 367-375
    • Antonelli, T.1    Tanganelli, S.2    Tomasini, M.C.3    Finetti, S.4    Trabace, L.5    Steardo, L.6    Sabino, V.7    Carratu, M.R.8    Cuomo, V.9    Ferraro, L.10
  • 4
    • 27744470790 scopus 로고    scopus 로고
    • Prenatal exposure to the CB1 receptor agonist WIN 55, 212-2 causes learning disruption associated with impaired cortical NMDA receptor function and emotional reactivity changes in rat offspring
    • T Antonelli MC Tomasini M Tattoli T Cassano S Tanganelli S Finetti E Mazzoni L Trabace L Steardo V Cuomo L Ferraro 2005 Prenatal exposure to the CB1 receptor agonist WIN 55, 212-2 causes learning disruption associated with impaired cortical NMDA receptor function and emotional reactivity changes in rat offspring Cereb Cortex 15 2013 2020
    • (2005) Cereb Cortex , vol.15 , pp. 2013-2020
    • Antonelli, T.1    Tomasini, M.C.2    Tattoli, M.3    Cassano, T.4    Tanganelli, S.5    Finetti, S.6    Mazzoni, E.7    Trabace, L.8    Steardo, L.9    Cuomo, V.10    Ferraro, L.11
  • 9
    • 0033198288 scopus 로고    scopus 로고
    • Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period
    • F Berrendero N Sepe JA Ramos V Di Marzo JJ Fernández-Ruiz 1999 Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period Synapse 33 181 191
    • (1999) Synapse , vol.33 , pp. 181-191
    • Berrendero, F.1    Sepe, N.2    Ramos, J.A.3    Di Marzo, V.4    Fernández-Ruiz, J.J.5
  • 10
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • TV Bliss GL Collingridge 1993 A synaptic model of memory: long-term potentiation in the hippocampus Nature 361 31 39
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.1    Collingridge, G.L.2
  • 12
    • 34547688878 scopus 로고    scopus 로고
    • Prenatal exposure to the cannabinoid receptor agonist WIN 55, 212-2 increases glutamate uptake through overexpression of GLT1 and EAAC1 glutamate transporter subtypes in rat frontal cerebral cortex
    • P Castaldo S Magi S Gaetani T Cassano L Ferraro T Antonelli S Amoroso V Cuomo 2007 Prenatal exposure to the cannabinoid receptor agonist WIN 55, 212-2 increases glutamate uptake through overexpression of GLT1 and EAAC1 glutamate transporter subtypes in rat frontal cerebral cortex Neuropharmacology 53 369 378
    • (2007) Neuropharmacology , vol.53 , pp. 369-378
    • Castaldo, P.1    Magi, S.2    Gaetani, S.3    Cassano, T.4    Ferraro, L.5    Antonelli, T.6    Amoroso, S.7    Cuomo, V.8
  • 13
    • 0028836926 scopus 로고
    • A longitudinal study of prenatal marijuana use. Effects on sleep and arousal at age 3 years
    • RE Dahl MS Scher DE Williamson N Robles N Day 1995 A longitudinal study of prenatal marijuana use. Effects on sleep and arousal at age 3 years Arch Pediatr Adolesc Med 149 145 150
    • (1995) Arch Pediatr Adolesc Med , vol.149 , pp. 145-150
    • Dahl, R.E.1    Scher, M.S.2    Williamson, D.E.3    Robles, N.4    Day, N.5
  • 15
  • 16
    • 0033538483 scopus 로고    scopus 로고
    • Role of endocannabinoids in brain development
    • Fernández-Ruiz JJ, Berrendero F, Hernández ML, Romero J, Ramos JA (1999) Role of endocannabinoids in brain development. Life Sci 65(6-7):725-736
    • (1999) Life Sci , vol.65 , Issue.6-7 , pp. 725-736
    • Fernández-Ruiz, J.J.1
  • 18
    • 0030887785 scopus 로고    scopus 로고
    • Cannabinoids excite dopamine neurons in the ventral tegmentum and substantia nigra
    • ED French K Dillon X Wu 1997 Cannabinoids excite dopamine neurons in the ventral tegmentum and substantia nigra Neuroreport 8 649 652
    • (1997) Neuroreport , vol.8 , pp. 649-652
    • French, E.D.1    Dillon, K.2    Wu, X.3
  • 19
    • 42349111669 scopus 로고    scopus 로고
    • Multiple roles for the endocannabinoid system during the earliest stages of life: Pre- and postnatal development
    • E Fride 2008 Multiple roles for the endocannabinoid system during the earliest stages of life: pre- and postnatal development J Neuroendocrinol 20 Suppl 1 75 81
    • (2008) J Neuroendocrinol , vol.20 , Issue.SUPPL 1 , pp. 75-81
    • Fride, E.1
  • 20
    • 0029890308 scopus 로고    scopus 로고
    • Developmental aspects of anandamide: Ontogeny of response and prenatal exposure
    • E Fride R Mechoulam 1996 Developmental aspects of anandamide: ontogeny of response and prenatal exposure Psychoneuroendocrinology 21 2 157 172
    • (1996) Psychoneuroendocrinology , vol.21 , Issue.2 , pp. 157-172
    • Fride, E.1    Mechoulam, R.2
  • 21
    • 0019977058 scopus 로고
    • Marihuana use by pregnant women and effects on offspring: An update
    • PA Fried 1982 Marihuana use by pregnant women and effects on offspring: an update Neurobehav Toxicol Teratol 4 4 451 454
    • (1982) Neurobehav Toxicol Teratol , vol.4 , Issue.4 , pp. 451-454
    • Fried, P.A.1
  • 22
    • 0036838949 scopus 로고    scopus 로고
    • Adolescents prenatally exposed to marijuana: Examination of facets of complex behaviors and comparisons with the influence of in utero cigarettes
    • PA Fried 2002 Adolescents prenatally exposed to marijuana: examination of facets of complex behaviors and comparisons with the influence of in utero cigarettes J Clin Pharmacol 42 97S 102S
    • (2002) J Clin Pharmacol , vol.42
    • Fried, P.A.1
  • 23
    • 0023601889 scopus 로고
    • Neonatal behavioural correlates of prenatal exposure to marihuana, cigarettes and alcohol in a low risk population
    • PA Fried JE Makin 1987 Neonatal behavioural correlates of prenatal exposure to marihuana, cigarettes and alcohol in a low risk population Neurotoxicol Teratol 9 1 7
    • (1987) Neurotoxicol Teratol , vol.9 , pp. 1-7
    • Fried, P.A.1    Makin, J.E.2
  • 24
    • 0035077403 scopus 로고    scopus 로고
    • A literature review of the consequences of prenatal marihuana exposure. An emerging theme of a deficiency in aspects of executive function
    • PA Fried AM Smith 2001 A literature review of the consequences of prenatal marihuana exposure. An emerging theme of a deficiency in aspects of executive function Neurotoxicol Teratol 23 1 11
    • (2001) Neurotoxicol Teratol , vol.23 , pp. 1-11
    • Fried, P.A.1    Smith, A.M.2
  • 25
    • 0024157498 scopus 로고
    • 12- and 24-month neurobehavioural follow-up of children prenatally exposed to marihuana, cigarettes and alcohol
    • PA Fried B Watkinson 1988 12- and 24-month neurobehavioural follow-up of children prenatally exposed to marihuana, cigarettes and alcohol Neurotoxicol Teratol 10 305 313
    • (1988) Neurotoxicol Teratol , vol.10 , pp. 305-313
    • Fried, P.A.1    Watkinson, B.2
  • 26
    • 0025047001 scopus 로고
    • 36- and 48-month neurobehavioral follow-up of children prenatally exposed to marijuana, cigarettes, and alcohol
    • PA Fried B Watkinson 1990 36- and 48-month neurobehavioral follow-up of children prenatally exposed to marijuana, cigarettes, and alcohol J Dev Behav Pediatr 11 49 58
    • (1990) J Dev Behav Pediatr , vol.11 , pp. 49-58
    • Fried, P.A.1    Watkinson, B.2
  • 27
    • 0033965160 scopus 로고    scopus 로고
    • Visuoperceptual functioning differs in 9- to 12-year olds prenatally exposed to cigarettes and marihuana
    • PA Fried B Watkinson 2000 Visuoperceptual functioning differs in 9- to 12-year olds prenatally exposed to cigarettes and marihuana Neurotoxicol Teratol 22 11 20
    • (2000) Neurotoxicol Teratol , vol.22 , pp. 11-20
    • Fried, P.A.1    Watkinson, B.2
  • 28
    • 0027029103 scopus 로고
    • 60- and 72-month follow-up of children prenatally exposed to marijuana, cigarettes, and alcohol: Cognitive and language assessment
    • PA Fried CM O'Connell B Watkinson 1992 60- and 72-month follow-up of children prenatally exposed to marijuana, cigarettes, and alcohol: cognitive and language assessment J Dev Behav Pediatr 13 383 391
    • (1992) J Dev Behav Pediatr , vol.13 , pp. 383-391
    • Fried, P.A.1    O'Connell, C.M.2    Watkinson, B.3
  • 29
    • 0033199818 scopus 로고    scopus 로고
    • Growth from birth to early adolescence in offspring prenatally exposed to cigarettes and marijuana
    • PA Fried B Watkinson R Gray 1999 Growth from birth to early adolescence in offspring prenatally exposed to cigarettes and marijuana Neurotoxicol Teratol 21 513 525
    • (1999) Neurotoxicol Teratol , vol.21 , pp. 513-525
    • Fried, P.A.1    Watkinson, B.2    Gray, R.3
  • 30
    • 0038120885 scopus 로고    scopus 로고
    • Differential effects on cognitive functioning in 13- to 16-year-olds prenatally exposed to cigarettes and marihuana
    • PA Fried B Watkinson R Gray 2003 Differential effects on cognitive functioning in 13- to 16-year-olds prenatally exposed to cigarettes and marihuana Neurotoxicol Teratol 25 427 436
    • (2003) Neurotoxicol Teratol , vol.25 , pp. 427-436
    • Fried, P.A.1    Watkinson, B.2    Gray, R.3
  • 31
    • 33745164608 scopus 로고    scopus 로고
    • Endocannabinoids: A new family of lipid mediators involved in the regulation of neural cell development
    • I Galve-Roperh T Aguado D Rueda G Velasco M Guzmán 2006 Endocannabinoids: a new family of lipid mediators involved in the regulation of neural cell development Curr Pharm Des 12 2319 2325
    • (2006) Curr Pharm des , vol.12 , pp. 2319-2325
    • Galve-Roperh, I.1    Aguado, T.2    Rueda, D.3    Velasco, G.4    Guzmán, M.5
  • 32
    • 0343554665 scopus 로고    scopus 로고
    • Perinatal delta(9)-tetrahydrocannabinol exposure alters the responsiveness of hypothalamic dopaminergic neurons to dopamine-acting drugs in adult rats
    • L García-Gil R de Miguel RM Muñoz M Cebeira MA Villanua JA Ramos JJ Fernández-Ruiz 1997 Perinatal delta(9)-tetrahydrocannabinol exposure alters the responsiveness of hypothalamic dopaminergic neurons to dopamine-acting drugs in adult rats Neurotoxicol Teratol 19 477 487
    • (1997) Neurotoxicol Teratol , vol.19 , pp. 477-487
    • García-Gil, L.1    De Miguel, R.2    Muñoz, R.M.3    Cebeira, M.4    Villanua, M.A.5    Ramos, J.A.6    Fernández-Ruiz, J.J.7
  • 33
    • 0031595207 scopus 로고    scopus 로고
    • Perinatal delta9-tetrahydrocannabinol exposure did not alter dopamine transporter and tyrosine hydroxylase mRNA levels in midbrain dopaminergic neurons of adult male and female rats
    • García-Gil L, Ramos JA, Rubino T, Parolaro D, Fernández- Ruiz JJ (1998) Perinatal delta9-tetrahydrocannabinol exposure did not alter dopamine transporter and tyrosine hydroxylase mRNA levels in midbrain dopaminergic neurons of adult male and female rats. Neurotoxicol Teratol 20(5):549-553
    • (1998) Neurotoxicol Teratol , vol.20 , Issue.5 , pp. 549-553
    • García-Gil, L.1
  • 34
    • 0032586991 scopus 로고    scopus 로고
    • Perinatal delta9-tetrahydrocannabinol exposure augmented the magnitude of motor inhibition caused by GABA(B), but not GABA(A), receptor agonists in adult rats
    • L Garcia-Gil R de Miguel J Romero A Perez JA Ramos JJ Fernández-Ruiz 1999 Perinatal delta9-tetrahydrocannabinol exposure augmented the magnitude of motor inhibition caused by GABA(B), but not GABA(A), receptor agonists in adult rats Neurotoxicol Teratol 21 277 283
    • (1999) Neurotoxicol Teratol , vol.21 , pp. 277-283
    • Garcia-Gil, L.1    De Miguel, R.2    Romero, J.3    Perez, A.4    Ramos, J.A.5    Fernández-Ruiz, J.J.6
  • 35
    • 0034611981 scopus 로고    scopus 로고
    • Effects of prenatal marijuana exposure on child behavior problems at age 10
    • L Goldschmidt NL Day GA Richardson 2000 Effects of prenatal marijuana exposure on child behavior problems at age 10 Neurotoxicol Teratol 22 325 336
    • (2000) Neurotoxicol Teratol , vol.22 , pp. 325-336
    • Goldschmidt, L.1    Day, N.L.2    Richardson, G.A.3
  • 39
    • 0034551774 scopus 로고    scopus 로고
    • Cannabinoids reveal the necessity of hippocampal neural encoding for short-term memory in rats
    • RE Hampson SA Deadwyler 2000 Cannabinoids reveal the necessity of hippocampal neural encoding for short-term memory in rats J Neurosci 20 8932 8942
    • (2000) J Neurosci , vol.20 , pp. 8932-8942
    • Hampson, R.E.1    Deadwyler, S.A.2
  • 42
    • 0026218146 scopus 로고
    • Five-year follow-up of rural Jamaican children whose mothers used marijuana during pregnancy
    • JS Hayes R Lampart MC Dreher L Morgan 1991 Five-year follow-up of rural Jamaican children whose mothers used marijuana during pregnancy West Indian Med J 40 120 123
    • (1991) West Indian Med J , vol.40 , pp. 120-123
    • Hayes, J.S.1    Lampart, R.2    Dreher, M.C.3    Morgan, L.4
  • 43
    • 0025954862 scopus 로고
    • Characterization and localization of cannabinoid receptors in rat brain: A quantitative in vitro autoradiographic study
    • M Herkenham AB Lynn MR Johnson LS Melvin BR de Costa KC Rice 1991 Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study J Neurosci 11 563 583
    • (1991) J Neurosci , vol.11 , pp. 563-583
    • Herkenham, M.1    Lynn, A.B.2    Johnson, M.R.3    Melvin, L.S.4    De Costa, B.R.5    Rice, K.C.6
  • 44
  • 45
    • 28844445679 scopus 로고    scopus 로고
    • Maternal smoking, drinking or cannabis use during pregnancy and neurobehavioral and cognitive functioning in human offspring
    • AC Huizink EJ Mulder 2006 Maternal smoking, drinking or cannabis use during pregnancy and neurobehavioral and cognitive functioning in human offspring Neurosci Biobehav Rev 30 24 41
    • (2006) Neurosci Biobehav Rev , vol.30 , pp. 24-41
    • Huizink, A.C.1    Mulder, E.J.2
  • 46
    • 0022501316 scopus 로고
    • Rat pup ultrasonic isolation calls: Possible mediation by the benzodiazepine receptor complex
    • TR Insel JL Hill RB Mayor 1986 Rat pup ultrasonic isolation calls: possible mediation by the benzodiazepine receptor complex Pharmacol Biochem Behav 24 1263 1267
    • (1986) Pharmacol Biochem Behav , vol.24 , pp. 1263-1267
    • Insel, T.R.1    Hill, J.L.2    Mayor, R.B.3
  • 47
  • 48
    • 0035800473 scopus 로고    scopus 로고
    • Stereotyped position of local synaptic targets in neocortex
    • J Kozloski F Hamzei-Sichani R Yuste 2001 Stereotyped position of local synaptic targets in neocortex Science 293 868 872
    • (2001) Science , vol.293 , pp. 868-872
    • Kozloski, J.1    Hamzei-Sichani, F.2    Yuste, R.3
  • 50
    • 0037444550 scopus 로고    scopus 로고
    • Glutamate promotes proliferation of striatal neuronal progenitors by an NMDA receptor-mediated mechanism
    • KC Luk TE Kennady AF Sadikot 2003 Glutamate promotes proliferation of striatal neuronal progenitors by an NMDA receptor-mediated mechanism J Neurosci 23 2239 2255
    • (2003) J Neurosci , vol.23 , pp. 2239-2255
    • Luk, K.C.1    Kennady, T.E.2    Sadikot, A.F.3
  • 51
    • 33645774927 scopus 로고    scopus 로고
    • Distribution of cannabinoid receptors in the central and peripheral nervous system
    • K Mackie 2005 Distribution of cannabinoid receptors in the central and peripheral nervous system Handb Exp Pharmacol 168 299 325
    • (2005) Handb Exp Pharmacol , vol.168 , pp. 299-325
    • MacKie, K.1
  • 52
    • 0026679317 scopus 로고
    • Localization of cannabinoid receptor in the human developing and adult basal ganglia. Higher levels in the striatonigral neurons
    • P Mailleux JJ Vanderhaeghen 1992 Localization of cannabinoid receptor in the human developing and adult basal ganglia. Higher levels in the striatonigral neurons Neurosci Lett 148 173 176
    • (1992) Neurosci Lett , vol.148 , pp. 173-176
    • Mailleux, P.1    Vanderhaeghen, J.J.2
  • 53
    • 0038730716 scopus 로고    scopus 로고
    • Ontogenetic development of cannabinoid receptor expression and signal transduction functionality in the human brain
    • S Mato E Del Olmo A Pazos 2003 Ontogenetic development of cannabinoid receptor expression and signal transduction functionality in the human brain Eur J Neurosci 17 1747 1754
    • (2003) Eur J Neurosci , vol.17 , pp. 1747-1754
    • Mato, S.1    Del Olmo, E.2    Pazos, A.3
  • 55
    • 0028841944 scopus 로고
    • Behavioural consequences of maternal exposure to natural cannabinoids in rats
    • M Navarro P Rubio FR de Fonseca 1995 Behavioural consequences of maternal exposure to natural cannabinoids in rats Psychopharmacology 122 1 14
    • (1995) Psychopharmacology , vol.122 , pp. 1-14
    • Navarro, M.1    Rubio, P.2    De Fonseca, F.R.3
  • 56
    • 0029670237 scopus 로고    scopus 로고
    • Perinatal cannabinoid exposure modifies the sociosexual approach behavior and the mesolimbic dopaminergic activity of adult male rats
    • M Navarro R de Miguel F Rodríguez de Fonseca JA Ramos JJ Fernández-Ruiz 1996 Perinatal cannabinoid exposure modifies the sociosexual approach behavior and the mesolimbic dopaminergic activity of adult male rats Behav Brain Res 75 91 98
    • (1996) Behav Brain Res , vol.75 , pp. 91-98
    • Navarro, M.1    De Miguel, R.2    Rodríguez De Fonseca, F.3    Ramos, J.A.4    Fernández-Ruiz, J.J.5
  • 59
    • 0033921628 scopus 로고    scopus 로고
    • Cannabinoid receptor ligands: Clinical and neuropharmacological considerations, relevant to future drug discovery and development
    • RG Pertwee 2000 Cannabinoid receptor ligands: clinical and neuropharmacological considerations, relevant to future drug discovery and development Expert Opin Invest Drugs 9 1553 1571
    • (2000) Expert Opin Invest Drugs , vol.9 , pp. 1553-1571
    • Pertwee, R.G.1
  • 60
    • 33749314873 scopus 로고    scopus 로고
    • The acute effects of cannabinoids on memory in humans: A review
    • M Ranganathan DC D'Souza 2006 The acute effects of cannabinoids on memory in humans: a review Psychopharmacology (Berl) 188 425 444
    • (2006) Psychopharmacology (Berl) , vol.188 , pp. 425-444
    • Ranganathan, M.1    D'Souza, D.C.2
  • 61
    • 0029165715 scopus 로고
    • Prenatal alcohol, marijuana, and tobacco use: Infant mental and motor development
    • GA Richardson NL Day L Goldschmidt 1995 Prenatal alcohol, marijuana, and tobacco use: infant mental and motor development Neurotoxicol Teratol 17 479 487
    • (1995) Neurotoxicol Teratol , vol.17 , pp. 479-487
    • Richardson, G.A.1    Day, N.L.2    Goldschmidt, L.3
  • 62
  • 67
    • 0023897063 scopus 로고
    • The effects of prenatal alcohol and marijuana exposure: Disturbances in neonatal sleep cycling and arousal
    • MS Scher GA Richardson PA Coble NL Day DS Stoffer 1988 The effects of prenatal alcohol and marijuana exposure: disturbances in neonatal sleep cycling and arousal Pediatr Res 24 101 105
    • (1988) Pediatr Res , vol.24 , pp. 101-105
    • Scher, M.S.1    Richardson, G.A.2    Coble, P.A.3    Day, N.L.4    Stoffer, D.S.5
  • 68
    • 2942528872 scopus 로고    scopus 로고
    • Effects of prenatal marijuana on response inhibition: An fMRI study of young adults
    • AM Smith PA Fried MJ Hogan J Cameron 2004 Effects of prenatal marijuana on response inhibition: an fMRI study of young adults Neurotoxicol Teratol 26 533 542
    • (2004) Neurotoxicol Teratol , vol.26 , pp. 533-542
    • Smith, A.M.1    Fried, P.A.2    Hogan, M.J.3    Cameron, J.4
  • 69
    • 7544222031 scopus 로고    scopus 로고
    • Prenatal cannabinoid exposure down-regulates glutamate transporter expressions (GLAST and EAAC1) in the rat cerebellum
    • I Suárez G Bodega M Rubio JJ Fernández-Ruiz JA Ramos B Fernández 2004 Prenatal cannabinoid exposure down-regulates glutamate transporter expressions (GLAST and EAAC1) in the rat cerebellum Dev Neurosci 26 45 53
    • (2004) Dev Neurosci , vol.26 , pp. 45-53
    • Suárez, I.1    Bodega, G.2    Rubio, M.3    Fernández-Ruiz, J.J.4    Ramos, J.A.5    Fernández, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.