Determination of total retronecine esters-type hepatotoxic pyrrolizidine alkaloids in plant materials by pre-column derivatization high-performance liquid chromatography

Biomedical Chromatography

Volumn 23, Issue 6, 2009, Pages 665-671

  Xiong, Ai Zhen ^a   Yang, Li ^a   Zhang, Fang ^a   Yang, Xue Jing ^b   Wang, Chang Hong ^a   Wang, Zheng Tao ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

HPLC; Pre column derivative; Pyrrolizidine alkaloids; Quantitation

Indexed keywords

ALKALOIDS; COLUMN CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLITES;

CHLORANIL; DIODE ARRAY DETECTION; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; HPLC; PLANT MATERIAL; PRE-COLUMN DERIVATISATION; PRE-COLUMN DERIVATIVE; PYRROLIZIDINE ALKALOID; QUANTITATION; RETRONECINE;

ESTERS;

CHLORANIL; FORMIC ACID; METHANOL; PYRROLIZIDINE ALKALOID; RETRONECINE; TRIETHYLAMINE; 2 CHLORANIL; 2-CHLORANIL; DRUG DERIVATIVE; PLANT EXTRACT; TOXIN;

ACCURACY; ARTICLE; CONTROLLED STUDY; ELECTROCHEMICAL DETECTION; HERB; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIGULARIA DUCIFORMIS; LIGULARIA HODGSONII; NONHUMAN; PROCESS OPTIMIZATION; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SENECIO SCANDENS; SENSITIVITY AND SPECIFICITY; CHEMISTRY; HEAT; HUMAN; INSTRUMENTATION; ISOLATION AND PURIFICATION; MEDICINAL PLANT; METHODOLOGY; OXIDATION REDUCTION REACTION; VALIDATION STUDY;

CHLORANIL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HOT TEMPERATURE; HUMANS; METHANOL; OXIDATION-REDUCTION; PLANT EXTRACTS; PLANTS, MEDICINAL; PYRROLIZIDINE ALKALOIDS; SENSITIVITY AND SPECIFICITY; TOXINS, BIOLOGICAL;

EID: 67651214389     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1172     Document Type: Article

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