A single course of rituximab does not abrogate anti-infliximab antibodies in patients with rheumatoid arthritis

Annals of the Rheumatic Diseases

Volumn 68, Issue 8, 2009, Pages 1368-1369

  Van Den Bemt, B J F ^a   Vos, K ^b,e   Den Broeder, A A ^c   Blom, M ^d   Thurlings, R M ^b   Bartelds, G M ^e   Stapel, S O ^f   Barrera, P ^d   Tak, P P ^b   Nurmohamed, M T ^e   Wolbink, G J ^f  

^a SINT MAARTENSKLINIEK   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c Sint Maartenskliniek ^*  (Netherlands)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^e JAN VAN BREEMEN INSTITUTE   (Netherlands)

^f SANQUIN RESEARCH   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; ANTIBODY; AZATHIOPRINE; CORTICOSTEROID; INFLIXIMAB; INFLIXIMAB ANTIBODY; LEFLUNOMIDE; METHOTREXATE; RITUXIMAB; UNCLASSIFIED DRUG;

ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; DRUG EFFECT; HUMAN; LETTER; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RHEUMATOID ARTHRITIS; SEROCONVERSION; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADULT; AGED; ANTIBODIES; ANTIBODIES, MONOCLONAL; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; FEMALE; HUMANS; MALE; MIDDLE AGED;

EID: 67651211164     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2008.095448     Document Type: Letter

References (3)

1. Maini RN, Breedveld FC, Kalden JR, Smolen JS, Davis D, Macfarlane JD, et al. Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum 1998;41:1552-63.
2. Bendtzen K, Geborek P, Svenson M, Larsson L, Kapetanovic MC, Saxne T. Individualized monitoring of drug bioavailability and immunogenicity in rheumatoid arthritis patients treated with the tumor necrosis factor alpha inhibitor infliximab. Arthritis Rheum 2006;54:3782-9.
3. Wolbink GJ, Vis M, Lems W, Voskuyl AE, de Groot E, Nurmohamed MT, et al. Development of antiinfliximab antibodies and relationship to clinical response in patients with rheumatoid arthritis. Arthritis Rheum 2006;54:711-15.