Metastatic lymph node ratio is an independent prognostic factor in gastric cancer

Hepato-Gastroenterology

Volumn 56, Issue 91-92, 2009, Pages 908-913

  Asoglu, Oktar ^a,c   Karanlik, Hasan ^b   Parlak, Mesut ^a   Kecer, Mustafa ^a   Muslumanoglu, Mahmut ^a   Igci, Abdullah ^a   Ozmen, Vahit ^a   Gulluoglu, Mine ^a   Kapran, Yersu ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

^c NONE   (Turkey)

Author keywords

Gastric cancer; Lymph node metastasis; Metastatic lymph node ratio; Prognosis

Indexed keywords

ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER RISK; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HIGH RISK POPULATION; HUMAN; HUMAN TISSUE; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROGNOSIS; STOMACH CANCER;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; COHORT STUDIES; FEMALE; GASTRECTOMY; HUMANS; KAPLAN-MEIERS ESTIMATE; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; RISK FACTORS; STOMACH NEOPLASMS; YOUNG ADULT;

EID: 67651208048     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Harrison JD, Fielding JW: Prognostic factors for gastric cancer influencing clinical practice. World J Surg 1995; 19:496-500.
2. Adachi Y, Shiraishi N, Suematsu T, et al: Most important lymph node information in gastric cancer: multivariate prognostic study. Ann Surg Oncol 2000; 7:503-507. (Pubitemid 30666489)
3. Okusa T, Nakane Y, Boku T, et al: Quantitative analysis of nodal involvement with respect to survival rate after curative gastrectomy for carcinoma. Surg Gynecol Obstet 1990; 170:488-494. (Pubitemid 20220148)
4. Makino M, Moriwaki S, Yonekawa M, et al: Prognostic significance of the number of metastatic lymph nodes in patients with gastric cancer. J Surg Oncol 1991; 47:12-16.
5. Yu W, Choi GS, Whang I, et al: Comparison of five systems for staging lymph node metastasis in gastric cancer. Br J Surg 1997; 84:1305-1309. (Pubitemid 27400290)
6. Karpeh MS, Leon L, Klimstra D, et al: Lymph node staging in gastric cancer: is location more important than Number? An analysis of 1,038 patients. Ann Surg 2000; 232:362-371. (Pubitemid 30677824)
7. Roviello F, Rossi S, Marrelli D, et al: Number of lymph node metastases and its prognostic significance in early gastric cancer: a multicenter Italian study. J Surg Oncol 2006; 94:275-280 (Pubitemid 44330849)
8. Japanese Gastric Cancer Association: Japanese Classification of Gastric Carcinoma - 2nd English Edition - Gastric Cancer 1998; 1:10-24.
9. Sobin LH, Wittekind C: TNM classification of malignant tumors. 6th Edition. New York: Wiley-Liss, 2002; pp. 65-68.
10. Roder JD, Bottcher K, Busch R, et al: Classification of regional lymph node metastasis from gastric carcinoma. German Gastric Cancer Study Group. Cancer 1998; 82:621-631. (Pubitemid 28090271)
11. Fujii K, Isozaki H, Okajima K, et al: Clinical evaluation of lymph node metastasis in gastric cancer defined by the fifth edition of the TNM classification in comparison with the Japanese system. Br J Surg 1999; 86:685-689. (Pubitemid 29248366)
12. Hayashi H, Ochiai T, Suzuki T, et al: Superiority of a new UICC-TNM staging system for gastric carcinoma. Surgery 2000; 127:129-135. (Pubitemid 30091256)
13. Bouvier AM, Haas O, Piard F, et al: How many nodes must be examined to accurately stage gastric carcinomas? Results from a population based study. Cancer 2002; 94:2862-2866. (Pubitemid 34547684)
14. Hartgrink HH, van de Velde CJ, Putter H, et al: Extended lymph node dissection for gastric cancer: who may benefit? Final results of the randomized Dutch gastric cancer group trial. J Clin Oncol 2004; 22:2069-2077. (Pubitemid 41095139)
15. Bando E, Yonemura Y, Taniguchi K, et al: Outcome of ratio of lymph node metastasis in gastric carcinoma. Ann Surg Oncol 2002; 9:775-784.
16. Inoue K, Nakane Y, Iiyama H, et al: The superiority of ratio-based lymph node staging in gastric carcinoma. Ann Surg Oncol 2002; 9:27-34. (Pubitemid 34262894)
17. Wu CW, Hsiung CA, Lo SS, et al: Stage migration influences on stage-specific survival comparison between D1 and D3 gastric cancer surgeries. Eur J Surg Oncol 2005; 31:153-157. (Pubitemid 40214750)
18. Siewert JR, Bottcher K, Stein HJ, et al: Relevant prognostic factors in gastric cancer: ten-year results of the German Gastric Cancer Study. Ann Surg 1998; 228:449-461. (Pubitemid 30194389)
19. Bostanci EB, Kayaalp C, Ozogul Y, et al: Comparison of complications after D2 and D3 dissection for gastric cancer. Eur J Surg Oncol 2004; 30:20-25. (Pubitemid 38180987)
20. Kodera Y, Yamamura Y, Shimizu Y, et al: Lymph node status assessment for gastric carcinoma: is the number of metastatic lymph nodes really practical as a parameter for N categories in the TNM Classification? Tumor Node Metastasis. J Surg Oncol 1998; 69:15-20. (Pubitemid 28452268)
21. Hyung WJ, Noh SH, Yoo CH, et al: Prognostic significance of metastatic lymph node ratio in T3 gastric cancer. World J Surg 2002; 26:323-329. (Pubitemid 36920410)
22. Katai H, Yoshimura K, Maruyama K, et al: Evaluation of the New International Union Against Cancer TNM staging for gastric carcinoma. Cancer 2000; 88:1796-1800 (Pubitemid 30212987)
23. Peeters KC, Hundahl SA, Kranenbarg EK, et al: Low Maruyama index surgery for gastric cancer: blinded reanalysis of the Dutch D1-D2 trial. World J Surg 2005; 29:1576-1584. (Pubitemid 41779858)
24. Nitti D, Marchet A, Olivieri M, et al: Ratio between metastatic and examined lymph nodes is an independent prognostic factor after D2 resection for gastric cancer: analysis of a large European monoinstitutional experience. Ann Surg Oncol 2003; 10:1077-1085. (Pubitemid 40486832)
25. Rodriguez Santiago JM, Munoz E, Marti M, et al: Metastatic lymph node ratio as a prognostic factor in gastric cancer. Eur J Surg Oncol 2005; 31:59-66. (Pubitemid 40103926)
26. Kodera Y, Yamamura Y, Shimizu Y, et al: Metastatic gastric lymph node rate is a significant prognostic factor for resectable stage IV stomach cancer. J Am Coll Surg 1997; 185:65-69. (Pubitemid 27276744)
27. Costa ML, de Cassia Braga Ribeiro K, Machado MA, et al: Prognostic score in gastric cancer: the importance of a conjoint analysis of clinical, pathologic, and therapeutic factors. Ann Surg Oncol 2006; 13:843-850. (Pubitemid 43727369)
28. Cheong JH, Hyung WJ, Shen JG, et al: The N ratio predicts recurrence and poor prognosis in patients with node- positive early gastric cancer. Ann Surg Oncol 2006; 13:377-385. (Pubitemid 43255922)
29. Bunt AM, Hogendoorn PC, van de Velde CJ, et al: Lymph node staging standards in gastric cancer. J Clin Oncol 1995; 13:2309-2316.
30. Noguchi Y, Imada T, Matsumoto A, et al: Radical surgery for gastric cancer. A review of the Japanese experience. Cancer 1989; 64:2053-2062.
31. Nitti D, Marchet A, Mammano E, et al: Extended lymphadenectomy (D2) in patients with early gastric cancer. Eur J Surg Oncol 2005; 31:875-881.