Ontological and ethical implications of direct nuclear reprogramming: Response to magill and neaves

Kennedy Institute of Ethics Journal

Volumn 19, Issue 1, 2009, Pages 33-40

  Condic, Maureen L ^a   Lee, Patrick ^a   George, Robert P ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 67651204314     PISSN: 10546863     EISSN: None     Source Type: Journal    
DOI: 10.1353/ken.0.0275     Document Type: Article

References (10)

1. Eakin Guy S.; Hadjantonakis, Anna-Katerina; Papaioannou, Virginia E.; and Behringer, Richard R. 2005. Developmental Potential and Behavior of Tetraploid Cells in the Mouse Embryo. Developmental Biology 288 (1):150-59.
2. Goto, Yuji; Matsui, Junko; and Takagi, Nobuo. 2002. Developmental Potential of Mouse Tetraploid Cells in Diploid ↔ Tetraploid Chimeric Embryos. International Journal of Developmental Biology 46: 741-45.
3. Ishiguro, Naomi; Kano, Kiyoshi; Yamamoto, Yoshio; and Taniguchi, Kazuyuki. 2005. Tetraploid Cells of Enhanced Green Fluorescent Protein Transgenic Mice in Tetraploid/Diploid-Chimeric Embryos. Journal of Reproduction and Development 51: 567-72.
4. Li, Xiangyun; Yu, Yuansong; Wei, Wei; et al. 2005. Simple and Efficient Production of Mice Derived from Embryonic Stem Cells Aggregated with Tetraploid Embryos. Molecular Reproduction and Development 71: 154-58.
5. Mackay, Gillian E., and West, John D. 2005. Fate of Tetraploid Cells in 4n↔2n Chimeric Mouse Blastocysts. Mechanisms of Development 122: 1266-81.
6. Magill, Gerard, and Neaves, William B. 2009. Ontological and Ethical Implications of Direct Nuclear Reprogramming. Kennedy Institute of Ethics Journal 19: 23-32.
7. Nagy, A.; Gocza, E.; Diaz, E. M.; et al. 1990. Embryonic Stem Cells Alone Are Able to Support Fetal Development in the Mouse. Development 110: 815-21.
8. Poueymirou, William T.; Auerbach, Wojtek; Frendewey, David; et al. 2007. F0 Generation Mice Fully Derived from Gene-Targeted Embryonic Stem Cells Allowing Immediate Phenotypic Analyses. Nature Biotechnology 25 (1): 91-99.
9. Rossant, Janet. 2007. Stem Cells and Lineage Development in the Mammalian Blastocyst. Reproduction, Fertility, and Development 19 (1): 111-18.
10. Zhou, Qiao; Brown, Juliana; Kanarek, Andrew; et al. 2008. In Vivo Reprogramming of Adult Pancreatic Exocrine Cells to Beta-Cells. Nature 455: 627-32.