A chemical approach to immunoprotein engineering: Chemoselective functionalization of thioester proteins in their native state

ChemBioChem

Volumn 10, Issue 8, 2009, Pages 1340-1343

  Cole, Michael A ^a   Tully, Sarah E ^a,b   Dodds, Alister W ^a   Arnold, James N ^a,d   Boldt, Grant E ^a   Sim, Robert B ^a   Offer, John ^a,c   Wentworth Jr , Paul ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Activity based protein profiling; Hydrazides; Peptides; Proteins; Thioesters

Indexed keywords

ALPHA 2 MACROGLOBULIN; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; IMMUNOGLOBULIN; PROTEIN DERIVATIVE; THIOESTER; BIOTIN; COMPLEMENT COMPONENT C4B; FLUORESCENT DYE; PEPTIDE; THIOL DERIVATIVE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL MODIFICATION; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONFORMATION; HYDROLYSIS; KINETICS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN ENGINEERING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEOMICS; WESTERN BLOTTING; CHEMISTRY; IMMUNOLOGY;

ALPHA-MACROGLOBULINS; BIOTIN; COMPLEMENT C3; COMPLEMENT C4B; FLUORESCENT DYES; PEPTIDES; PROTEIN ENGINEERING; SULFHYDRYL COMPOUNDS;

EID: 67651176068     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200900168     Document Type: Article

References (17)

1. M. J. Walport, N. Engl. J. Med. 2001, 344, 1058.
2. M. C. Carroll, Nat. Immunol. 2004, 5, 981.
3. N. Doan, P. G. W. Gettins, Biochem. J. 2007, 407, 23.
4. B. F. Tack, R. A. Harrison, J. Janatova, M. L. Thomas, J. W. Prahl, Proc. Natl. Acad. Sci. USA 1980, 77, 5764.
5. S. K. A. Law, A. W. Dodds, Protein Sci. 1997, 6, 263.
6. B. J. C. Janssen, E. G. Huizinga, H. C. A. Raaijmakers, A. Roos, M. R. Daha, K. Nilsson-Ekdahl, B. Nilsson, P. Gros, Nature 2005, 437, 505.
7. P. Gros, F. J. Milder, B. J. C. Janssen, Nat. Rev. Immunol. 2008, 8, 48.
8. B. J. C. Janssen, A. Christodoulidou, A. McCarthy, J. D. Lambris, P. Gros, Nature 2006, 444, 213.
9. M. K. Pangburn, R. D. Schreiber, H. J. Müller-Eberhard, J. Exp. Med. 1981, 154, 856.
10. M. K. Pangburn, H. J. Müller-Eberhard, J. Exp. Med. 1980, 152, 1102.
11. J. P. Gorski, R. Silversmith, S. Fiebeger, T. Moilanen, J. Biol. Chem. 1982, 257, 10948.
12. R. B. Sim, E. Sim, Biochem. J. 1981, 193, 129.
13. R. P. Swenson, J. B. Howard, Proc. Natl. Acad. Sci. USA, 1979, 76, 4313.
14. D. E. Isenman, D. I. C. Kells, N. R. Cooper, H. J. Müller-Eberhard, M. K. Pangburn, Biochemistry 1981, 20, 4458.
15. D. T. Fearon, K. F. Austen, Proc. Natl. Acad. Sci. USA 1977, 74, 1683.
16. M. K. Pangburn, J. Immunol. 1989, 142, 2759.
17. A. E. Speers, B. F. Cravatt, ChemBioChem 2004, 5, 41.