메뉴 건너뛰기




Volumn 51, Issue 1, 2009, Pages 47-53

The structure and outcomes of a hiv postexposure prophylaxis program in a high hiv prevalence setup in Western Kenya

Author keywords

Health care worker; HIV; Postexposure prophylaxis; Sexual assault

Indexed keywords

ANTIRETROVIRUS AGENT; DOXYCYCLINE; ETHINYLESTRADIOL PLUS LEVONORGESTREL; LAMIVUDINE; LEVONORGESTREL; LOPINAVIR; NORFLOXACIN; RECOMBINANT HEPATITIS B VACCINE; RITONAVIR; RNA POLYMERASE; SPECTINOMYCIN; STAVUDINE; VIRUS RNA; ZIDOVUDINE;

EID: 67651174772     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAI.0b013e318198a96a     Document Type: Article
Times cited : (29)

References (36)
  • 1
    • 25444448727 scopus 로고    scopus 로고
    • Updated U.S. Public Health Service guidelines for the management of occupational exposures to HIV and recommendations for postexposure prophylaxis
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HIV and recommendations for postexposure prophylaxis. MMWR Recomm Rep. 2005;54(RR-9):1-24.
    • (2005) MMWR Recomm Rep , vol.54 , Issue.RR-9 , pp. 1-24
  • 2
    • 0030831196 scopus 로고    scopus 로고
    • Occupational risk of human immunodeficiency virus infection in health-care workers: An overview
    • Bell DM. Occupational risk of human immunodeficiency virus infection in health-care workers: an overview. Am J Med. 1997;102:9-15.
    • (1997) Am J Med , vol.102 , pp. 9-15
    • Bell, D.M.1
  • 3
    • 13744249434 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention. Antiretroviral postexposure prophylaxis after sexual, injection-drug use, or other nonoccupational exposure to HIV in the United States: recommendations from the U.S. Department of Health and Human Services. MMWR Recomm Rep. 2005; 54(No. RR-2):1-28.
    • Centers for Disease Control and Prevention. Antiretroviral postexposure prophylaxis after sexual, injection-drug use, or other nonoccupational exposure to HIV in the United States: recommendations from the U.S. Department of Health and Human Services. MMWR Recomm Rep. 2005; 54(No. RR-2):1-28.
  • 4
    • 36549011407 scopus 로고    scopus 로고
    • December, Geneva: UNAIDS; Available at:, Accessed March 26, 2009
    • UNAIDS. AIDS Epidemic Update, December 2007. Geneva: UNAIDS; 2007 Available at: http://data.unaids.org/pub/EPISlides/2007/2007-epiupdate-en.pdf. Accessed March 26, 2009.
    • (2007) AIDS Epidemic Update
  • 5
    • 9844249666 scopus 로고    scopus 로고
    • Profound immunosuppression across the spectrum of opportunistic disease among hospitalized HIVinfected adults in Abidjan, Cô te d'Ivoire
    • Grant AD, Djomand G, Smets P, et al. Profound immunosuppression across the spectrum of opportunistic disease among hospitalized HIVinfected adults in Abidjan, Cô te d'Ivoire. AIDS. 1997;11:1357-1364.
    • (1997) AIDS , vol.11 , pp. 1357-1364
    • Grant, A.D.1    Djomand, G.2    Smets, P.3
  • 6
    • 0038660869 scopus 로고    scopus 로고
    • CD4+ and CD8+ lymphocytes and clinical features of HIV seropositive Nigerians on presentation
    • Onyemelukewe GC, Musa BO. CD4+ and CD8+ lymphocytes and clinical features of HIV seropositive Nigerians on presentation. Afr J Med Med Sci. 2002;31:229-233.
    • (2002) Afr J Med Med Sci , vol.31 , pp. 229-233
    • Onyemelukewe, G.C.1    Musa, B.O.2
  • 7
    • 0034732201 scopus 로고    scopus 로고
    • Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group
    • Quinn TC, Wawer MJ, Sewankambo N, et al. Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group. N Engl J Med. 2000;342:921-929.
    • (2000) N Engl J Med , vol.342 , pp. 921-929
    • Quinn, T.C.1    Wawer, M.J.2    Sewankambo, N.3
  • 8
    • 84888537092 scopus 로고    scopus 로고
    • Kiragu K. On the Frontlines: Kenyan Health Workers Confront HIVRelated Challenges at Work and Home. The Population Council Inc Horizons report: HIV/AIDS operations research; June 2006. Available at: http://www.popcouncil. org/horizons/newsletter/horizons(12)-4.html. Accessed March 25, 2009.
    • Kiragu K. On the Frontlines: Kenyan Health Workers Confront HIVRelated Challenges at Work and Home. The Population Council Inc Horizons report: HIV/AIDS operations research; June 2006. Available at: http://www.popcouncil. org/horizons/newsletter/horizons(12)-4.html. Accessed March 25, 2009.
  • 9
    • 0034212338 scopus 로고    scopus 로고
    • Exposure to human immunodeficiency virus among healthcare workers in South Africa
    • Gounden YP, Moodley L. Exposure to human immunodeficiency virus among healthcare workers in South Africa. Int J Gynaecol Obstet. 2000; 69:265-270.
    • (2000) Int J Gynaecol Obstet , vol.69 , pp. 265-270
    • Gounden, Y.P.1    Moodley, L.2
  • 10
    • 20344366788 scopus 로고    scopus 로고
    • A descriptive, retrospective study of 567 accidental blood exposures in healthcare workers in three West African countries
    • Tarantola A, Koumare A, Rachline A, et al. A descriptive, retrospective study of 567 accidental blood exposures in healthcare workers in three West African countries. J Hosp Infect. 2005;60:276-282.
    • (2005) J Hosp Infect , vol.60 , pp. 276-282
    • Tarantola, A.1    Koumare, A.2    Rachline, A.3
  • 11
    • 33644695478 scopus 로고    scopus 로고
    • Genital injuries in women reporting sexual assault
    • Palmer CM, McNulty AM, D'Este C, et al. Genital injuries in women reporting sexual assault. Sex Health. 2004;1:55-159.
    • (2004) Sex Health , vol.1 , pp. 55-159
    • Palmer, C.M.1    McNulty, A.M.2    D'Este, C.3
  • 12
    • 1942457443 scopus 로고    scopus 로고
    • Prevalence of sexually transmitted infections and mental health needs of female child and adolescent survivors of rape and sexual assault attending a specialist clinic
    • Kawsar M, Anfield A, Walters E, et al. Prevalence of sexually transmitted infections and mental health needs of female child and adolescent survivors of rape and sexual assault attending a specialist clinic. Sex Transm Infect. 2004;80:138-141.
    • (2004) Sex Transm Infect , vol.80 , pp. 138-141
    • Kawsar, M.1    Anfield, A.2    Walters, E.3
  • 13
    • 38849110214 scopus 로고    scopus 로고
    • Association between sexual violence and psychiatric morbidity among HIV positive women in South Africa
    • Olley BO, Abrahams N, Stein DJ. Association between sexual violence and psychiatric morbidity among HIV positive women in South Africa. Afr J Med Med Sci. 2006;35(Suppl):143-147.
    • (2006) Afr J Med Med Sci , vol.35 , Issue.SUPPL. , pp. 143-147
    • Olley, B.O.1    Abrahams, N.2    Stein, D.J.3
  • 14
    • 33644913661 scopus 로고    scopus 로고
    • Posttraumatic stress disorder after occupational HIV exposure: Two cases and a literature review
    • Worthington MG, Ross JJ, Bergeron EK. Posttraumatic stress disorder after occupational HIV exposure: two cases and a literature review. Infect Control Hosp Epidemiol. 2006;27:215-217.
    • (2006) Infect Control Hosp Epidemiol , vol.27 , pp. 215-217
    • Worthington, M.G.1    Ross, J.J.2    Bergeron, E.K.3
  • 15
    • 0025974954 scopus 로고
    • Postexposure prophylaxis with zidovudine suppresses human immunodeficiency virus type 1 infection in SCID-hu mice in a time-dependent manner
    • Shih CC, Kaneshima H, Rabin L, et al. Postexposure prophylaxis with zidovudine suppresses human immunodeficiency virus type 1 infection in SCID-hu mice in a time-dependent manner. J Infect Dis. 1991;163: 625-627.
    • (1991) J Infect Dis , vol.163 , pp. 625-627
    • Shih, C.C.1    Kaneshima, H.2    Rabin, L.3
  • 16
    • 0030844266 scopus 로고    scopus 로고
    • Animal studies of prophylaxis
    • Black RJ. Animal studies of prophylaxis. Am J Med. 1997;102:39-44.
    • (1997) Am J Med , vol.102 , pp. 39-44
    • Black, R.J.1
  • 17
    • 0028003766 scopus 로고
    • Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group
    • Connor EM, Sperling RS, Gelber R, et al. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group. N Engl J Med. 1994;331:1173-1180.
    • (1994) N Engl J Med , vol.331 , pp. 1173-1180
    • Connor, E.M.1    Sperling, R.S.2    Gelber, R.3
  • 18
    • 79961039599 scopus 로고    scopus 로고
    • Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection
    • CD003510
    • Volmink J, Siegfried NL, van de Merwe L, et al. Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection. Cochrane Database Syst Rev. 2007;(1):CD003510.
    • Cochrane Database Syst Rev , vol.2007 , Issue.1
    • Volmink, J.1    Siegfried, N.L.2    van de Merwe, L.3
  • 19
    • 34247872923 scopus 로고    scopus 로고
    • Systematic review of the efficacy of antiretroviral therapies for reducing the risk of mother-to-child transmission of HIV infection
    • Suksomboon N, Poolsup N, Ket-Aim S. Systematic review of the efficacy of antiretroviral therapies for reducing the risk of mother-to-child transmission of HIV infection. J Clin Pharm Ther. 2007;32:293-311.
    • (2007) J Clin Pharm Ther , vol.32 , pp. 293-311
    • Suksomboon, N.1    Poolsup, N.2    Ket-Aim, S.3
  • 20
    • 0035283026 scopus 로고    scopus 로고
    • Feasibility of postexposure prophylaxis (PEP) against human immunodeficiency virus infection after sexual or injection drug use exposure: The San Francisco PEP Study
    • Kahn JO, Martin JN, Roland ME, et al. Feasibility of postexposure prophylaxis (PEP) against human immunodeficiency virus infection after sexual or injection drug use exposure: the San Francisco PEP Study. J Infect Dis. 2001;183:707-714.
    • (2001) J Infect Dis , vol.183 , pp. 707-714
    • Kahn, J.O.1    Martin, J.N.2    Roland, M.E.3
  • 21
    • 0030692781 scopus 로고    scopus 로고
    • A case-control study of HIV seroconversion in health care workers after percutaneous exposure. Centers for Disease Control and Prevention Needlestick Surveillance Group
    • Cardo DM, Culver DH, Ciesielski CA, et al. A case-control study of HIV seroconversion in health care workers after percutaneous exposure. Centers for Disease Control and Prevention Needlestick Surveillance Group. N Engl J Med. 1997;337:1485-1490.
    • (1997) N Engl J Med , vol.337 , pp. 1485-1490
    • Cardo, D.M.1    Culver, D.H.2    Ciesielski, C.A.3
  • 22
    • 34249792153 scopus 로고    scopus 로고
    • Antiretroviral post-exposure prophylaxis (PEP) for occupational HIV exposure
    • CD002835
    • Young TN, Arens FJ, Kennedy GE, et al. Antiretroviral post-exposure prophylaxis (PEP) for occupational HIV exposure. Cochrane Database Syst Rev. 2007;24:CD002835.
    • (2007) Cochrane Database Syst Rev , vol.24
    • Young, T.N.1    Arens, F.J.2    Kennedy, G.E.3
  • 23
    • 33646487888 scopus 로고    scopus 로고
    • Occupational HIV infection among health care workers exposed to blood and body fluids in Brazil
    • Rapparini C. Occupational HIV infection among health care workers exposed to blood and body fluids in Brazil. Am J Infect Dis. 2006;34: 237-240.
    • (2006) Am J Infect Dis , vol.34 , pp. 237-240
    • Rapparini, C.1
  • 24
    • 34548440364 scopus 로고    scopus 로고
    • Responding to the HIV pandemic: The power of an academic medical partnership
    • Einterz RM, Kimaiyo S, Mengech HN, et al. Responding to the HIV pandemic: the power of an academic medical partnership. Acad Med. 2007;88:812-818.
    • (2007) Acad Med , vol.88 , pp. 812-818
    • Einterz, R.M.1    Kimaiyo, S.2    Mengech, H.N.3
  • 26
    • 3042814812 scopus 로고    scopus 로고
    • Maternal toxicity with continuous nevirapine in pregnancy: Results from PACTG 1022
    • Hitti J, Frenkel LM, Stek AM, et al. Maternal toxicity with continuous nevirapine in pregnancy: results from PACTG 1022. J Acquir Immune Defic Syndr. 2004;36:772-776.
    • (2004) J Acquir Immune Defic Syndr , vol.36 , pp. 772-776
    • Hitti, J.1    Frenkel, L.M.2    Stek, A.M.3
  • 27
    • 33645629170 scopus 로고    scopus 로고
    • and, Department of Health and Human Services. Available at:, Accessed March 25, 2009
    • US Food and Drug Administration. FDA public health advisory for nevirapine (viramune). Department of Health and Human Services. Available at: http://www.fda.gov/Cder/drug/advisory/nevirapine.htm. Accessed March 25, 2009.
    • FDA public health advisory for nevirapine (viramune)
    • Food, U.S.1
  • 28
    • 0036467059 scopus 로고    scopus 로고
    • Severe ototoxicity in a health care worker who received postexposure prophylaxis with stavudine, lamivudine, and nevirapine after occupational exposure to HIV
    • Rey D, L'Heritier A, Lang JM. Severe ototoxicity in a health care worker who received postexposure prophylaxis with stavudine, lamivudine, and nevirapine after occupational exposure to HIV. Clin Infect Dis. 2002;34: 418-419.
    • (2002) Clin Infect Dis , vol.34 , pp. 418-419
    • Rey, D.1    L'Heritier, A.2    Lang, J.M.3
  • 29
    • 0035968189 scopus 로고    scopus 로고
    • Updated U.S. Public Health Service guidelines for the management of occupational exposures to HBV, HCV, and HIV and recommendations for postexposure prophylaxis
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention. Updated U.S. Public Health Service guidelines for the management of occupational exposures to HBV, HCV, and HIV and recommendations for postexposure prophylaxis. MMWR Recomm Rep. 2001;50(RR-11):1-42.
    • (2001) MMWR Recomm Rep , vol.50 , Issue.RR-11 , pp. 1-42
  • 30
    • 0032566466 scopus 로고    scopus 로고
    • Management of possible sexual, injecting-drug-use, or other nonoccupational exposure exposure to HIV, including considerations related to antiretroviral therapy: Public Health Service statement
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention. Management of possible sexual, injecting-drug-use, or other nonoccupational exposure exposure to HIV, including considerations related to antiretroviral therapy: Public Health Service statement. MMWR Recomm Rep. 1998; 47(RR-17):1-19.
    • (1998) MMWR Recomm Rep , vol.47 , Issue.RR-17 , pp. 1-19
  • 31
    • 84888533890 scopus 로고    scopus 로고
    • Violence against women and children in the era of HIV and AIDS: a situational analysis and response analysis in Kenya. The global coalition on women and AIDS. Nairobi, Kenya: UNAIDS; 2006. Available at: http://data.unaids. org/pub/Report/2006/20060630-gcwa-re-violence-women-girls-kenya-en.pdf. Accessed March 25, 2009.
    • Violence against women and children in the era of HIV and AIDS: a situational analysis and response analysis in Kenya. The global coalition on women and AIDS. Nairobi, Kenya: UNAIDS; 2006. Available at: http://data.unaids. org/pub/Report/2006/20060630-gcwa-re-violence-women-girls-kenya-en.pdf. Accessed March 25, 2009.
  • 32
    • 33745714184 scopus 로고    scopus 로고
    • Use of human immunodeficiency virus postexposure prophylaxis in adolescent sexual assault victims
    • Olshen E, Hsu K, Woods ER, et al. Use of human immunodeficiency virus postexposure prophylaxis in adolescent sexual assault victims. Arch Pediatr Adolesc Med. 2006;160:754-755.
    • (2006) Arch Pediatr Adolesc Med , vol.160 , pp. 754-755
    • Olshen, E.1    Hsu, K.2    Woods, E.R.3
  • 33
    • 15744399834 scopus 로고    scopus 로고
    • Postexposure prophylaxis after sexual assaults: A prospective cohort study
    • Garcia MT, Figueiredo RN, Moretti ML, et al. Postexposure prophylaxis after sexual assaults: a prospective cohort study. Sex Transm Dis. 2005;32: 214-219.
    • (2005) Sex Transm Dis , vol.32 , pp. 214-219
    • Garcia, M.T.1    Figueiredo, R.N.2    Moretti, M.L.3
  • 34
    • 23944523674 scopus 로고    scopus 로고
    • Human immunodeficiency virus postexposure prophylaxis in child and adolescent victims of sexual assault
    • Schremmer RD, Swanson D, Kraly K. Human immunodeficiency virus postexposure prophylaxis in child and adolescent victims of sexual assault. Pediatr Emerg Care. 2005;21:502-506.
    • (2005) Pediatr Emerg Care , vol.21 , pp. 502-506
    • Schremmer, R.D.1    Swanson, D.2    Kraly, K.3
  • 35
    • 85127211129 scopus 로고    scopus 로고
    • Meel BL. HIV/AIDS post-exposure prophylaxis (PEP) for victims of sexual assault in South Africa. Med Sci Law. 2005;45:219-224.
    • Meel BL. HIV/AIDS post-exposure prophylaxis (PEP) for victims of sexual assault in South Africa. Med Sci Law. 2005;45:219-224.
  • 36
    • 20444480291 scopus 로고    scopus 로고
    • HIV postexposure prophylaxis in sexual assault: Current practice and patient adherence to treatment recommendations in a large urban teaching hospital
    • Linden JA, Oldeg P, Mehta SD, et al. HIV postexposure prophylaxis in sexual assault: current practice and patient adherence to treatment recommendations in a large urban teaching hospital. Acad Emerg Med. 2005;12:640-646.
    • (2005) Acad Emerg Med , vol.12 , pp. 640-646
    • Linden, J.A.1    Oldeg, P.2    Mehta, S.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.