Micronutrient prenatal supplementation prevents the development of hypertension and vascular endothelial damage induced by intrauterine malnutrition

Life Sciences

Volumn 85, Issue 7-8, 2009, Pages 327-333

  Franco, Maria do Carmo ^a   Ponzio, Beatriz Felice ^a   Gomes, Guiomar Nascimento ^b   Gil, Frida Zaladek ^b   Tostes, Rita ^a,c   Carvalho, Maria Helena Catelli ^a   Fortes, Zuleica Bruno ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Blood pressure; Diet; Endothelial function; Pregnancy; Prenatal supplementation

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; FOLIC ACID; MINERAL; NITRIC OXIDE; SELENIUM; SUPEROXIDE; TRACE ELEMENT; VITAMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; BLOOD VESSEL REACTIVITY; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DIETARY INTAKE; ENDOTHELIUM LESION; FEMALE; HYPERTENSION; KIDNEY DISEASE; KIDNEY FUNCTION; MALNUTRITION; MORPHOMETRICS; NONHUMAN; PREGNANCY; PRENATAL PERIOD; PROGENY; SUPPLEMENTATION; VASODILATATION;

ANIMALS; AORTA, THORACIC; BLOOD PRESSURE; DIETARY SUPPLEMENTS; ENDOTHELIUM, VASCULAR; FEMALE; FETAL NUTRITION DISORDERS; HYPERTENSION; KIDNEY; KIDNEY FUNCTION TESTS; MICRONUTRIENTS; NITRIC OXIDE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; SUPEROXIDES; VASODILATION;

RATTUS NORVEGICUS;

EID: 67651172755     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2009.06.013     Document Type: Article

References (37)

1. Achón M., Reyes L., Alonso-Aperte E., Ubeda N., and Varela-Moreiras G. High dietary folate supplementation affects gestational development and dietary protein utilization in rats. Journal of Nutrition 129 (1999) 1204-1208
2. Ahn Y.M., Kim Y.J., Park H., Park B., and Lee H. Prenatal vitamin C status is associated with placental apoptosis in normal-term human pregnancies. Placenta 28 (2007) 31-38
3. Ashworth C.J., and Antipatis C. Micronutrient programming of development throughout gestation. Reproduction 122 (2001) 527-535
4. Barker D.J.P. Fetal origins of coronary heart disease. British Medical Journal 311 (1995) 171-174
5. Brigelius-flohé R., Banning A., and Schnurr K. Selenium-dependent enzymes in endothelial cell function. Antioxidant Redox Signal 5 (2003) 205-215
6. Burrow C.R. Retinoids and renal development. Experimental Nephrology8 (2000) 219-225
7. Cambonie G., Comt B., Yzydorczyk C., Germain N., Pladys P., Gauthier C., Lahaie I., Abran D., Lavoie J.C., and Nuyt A.M. Antenatal antioxidant prevents adult hypertension, vascular dysfunction, and microvascular rarefaction associated with in utero exposure to a low-protein diet. The American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 292 (2007) R1236-R1245
8. Carr A.C., Zhu B.Z., and Frei B. Potential antiatherogenic mechanisms of ascorbate (vitamin C) and alpha-tocopherol (vitamin E). Circulation Research 87 (2000) 349-354
9. Ceravolo G.S., Franco M.C., Carneiro-Ramos M.S., Barreto-Chaves M.L., Tostes R.C., Nigro D., Fortes Z.B., and Carvalho M.H. Enalapril and losartan restored blood pressure and vascular reactivity in intrauterine undernourished rats. Life Sciences 80 (2007) 782-787
10. Dashman T., Horst D., Bautz G., and Kamm J.J. Ascorbic acid: effect of high doses on brain and heart catecholamine levels in guinea-pigs and rats. Experientia 29 (1973) 832-843
11. Dennery P.A. Effects of oxidative stress on embryonic development. Birth Defects Research Part C: Embryo Today 81 (2007) 155-162
12. Franco M.C., Arruda R.M., Dantas A.P., Kawamoto E.M., Fortes Z.B., Scavone C., Carvalho M.H., Tostes R.C., and Nigro D. Intrauterine undernutrition: expression and activity of the endothelial nitric oxide synthase in male and female adult offspring. Cardiovascular Research 56 (2002) 145-153
13. Franco M.C., Akamine E.H., Di Marco G.S., Casarini D.E., Fortes Z.B., Tostes R.C., Carvalho M.H., and Nigro D. NADPH oxidase and enhanced superoxide generation in intrauterine undernourished rats: involvement of the renin-angiotensin system. Cardiovascular Research 59 (2003) 767-775
14. Franco M.C., Fortes Z.B., Akamine E.H., Kawamoto E.M., de Britto L.R., Muscara M.N., Teixeira S.A., Tostes R.C., Carvalho M.H., and Nigro D. Tetrahydrobiopterin improves endothelial dysfunction and vascular oxidative stress in microvessels of intrauterine undernourished rats. Journal of Physiology (London) 558 (2004) 239-248
15. González-Correa J.A., Arrebola M.M., Guerrero A., Cañada M.J., Muñoz M.J., Sánchez De la Cuesta F., and De la Cruz J.P. Antioxidant and antiplatelet effects of the alpha-tocopherol-aspirin combination in type 1-like diabetic rats. Life Sciences 79 (2006) 1405-1412
16. Gupta P., Narang M., Banerjee B.D., and Basu S. Oxidative stress in term small for gestational age neonates born to undernourished mothers: a case control study. BMC Pediatric 20 (2004) 4-14
17. Jansson T., and Powell T.L. Role of the placenta in fetal programming: underlying mechanisms and potential interventional approaches. Clinical Science 113 (2007) 1-13
18. Jenkins C., Wilson R., Roberts J., Miller H., McKillop J.H., and Walker J.J. Antioxidants: their role in pregnancy and miscarriage. Antioxidant Redox Signal 2 (2000) 623-628
19. Lee B.E., Hong Y.C., Lee K.H., Kim Y.J., Kim W.K., Chang N.S., Park E.A., Park H.S., and Hann H.J. Influence of maternal serum levels of vitamins C and E during the second trimester on birth weight and length. European Journal of Clinical Nutrition 58 (2004) 1365-1371
20. Lillycrop K.A., Phillips E.S., Jackson A.A., Hanson M.A., and Burdge G.C. Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. Journal of Nutrition 135 (2005) 1382-1386
21. Lucas S.R., Costa Silva V.L., Miraglia S.M., and Zaladek Gil F. Functional and morphometric evaluation of offspring kidney after intrauterine undernutrition. Pediatric Nephrology 11 (1997) 719-723
22. Luo Z.C., Fraser W.D., Julien P., Deal C.L., Audibert F., Smith G.N., Xiong X., and Walker M. Tracing the origins of "fetal origins" of adult diseases: programming by oxidative stress?. Medical Hypotheses 66 (2006) 38-44
23. Makrakis J., Zimanyi M.A., and Black M.J. Retinoic acid enhances nephron endowment in rats exposed to maternal protein restriction. Pediatric Nephrology 22 (2007) 1861-1867
24. Miller F.J., Gutterman D.D., Rios C.D., Heistad D.D., and Davidson B.L. Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis. Circulation Research 82 (1998) 1298-1305
25. Moens A.L., Vrints C.J., Claeys M.J., Timmermans J.P., Champion H.C., and Kass D.A. Mechanisms and potential therapeutic targets for folic acid in cardiovascular disease. The American Journal of Physiology - Heart and Circulatory Physiology 294 (2008) H1971-H1977
26. Myatt L. Placental adaptive responses and fetal programming. Journal of Physiology (London) 572 (2006) 25-30
27. Peng Y., Kwok K.H., Yang P.H., Liu J., Wong O.G., He M.L., Kung H.F., Lin M.C., and Ascorbic acid inhibits R.O.S. production, NF-kappa B activation and prevents ethanol-induced growth retardation and microencephaly. Neuropharmacology 48 (2005) 426-434
28. Poston L., Briley A.L., Seed P.T., Kelly F.J., and Shennan A.H. Vitamins in Pre-eclampsia (VIP) Trial Consortium. Vitamin C and vitamin E in pregnant women at risk for pre-eclampsia (VIP trial): randomised placebo-controlled trial. Lancet 367 (2006) 1145-1154
29. Racasan S., Braam B., van der Giezen D.M., Goldschmeding R., Boer P., Koomans H.A., and Joles J.A. Perinatal l-arginine and antioxidant supplements reduce adult blood pressure in spontaneously hypertensive rats. Hypertension 44 (2004) 83-88
30. Racasan S., Braam B., Koomans H.A., and Joles J.A. Programming blood pressure in adult SHR by shifting perinatal balance of NO and reactive oxygen species toward NO: the inverted Barker phenomenon. The American Journal of Physiology - Renal Physiology 288 (2005) F626-F636
31. Rumbold A., Duley L., Crowther C.A., and Haslam R.R. Antioxidants for preventing pre-eclampsia. Cochrane Database System Review 23 (2008) CD004227
32. Saintonge J., and Rosso P. Placental blood flow and transfer of nutrient analogs in large, average, and small guinea pig littermates. Pediatric Research 15 (1981) 152-156
33. Smith C.H., Moe A.J., and Ganapathy V. Nutrient transport pathways across the epithelium of the placenta. Annual Review of Nutrition 12 (1992) 183-206
34. Torrens C., Brawley L., Anthony F.W., Dance C.S., Dunn R., Jackson A.A., Poston L., and Hanson M.A. Folate supplementation during pregnancy improves offspring cardiovascular dysfunction induced by protein restriction. Hypertension 47 (2006) 982-987
35. Vaziri N.D., Zhenmin N., Oveisi F., and Trnavsk-hobbs D.L. Effect of antioxidant therapy on blood pressure and NO synthase expression in hypertensive rats. Hypertension 36 (2000) 957-964
36. Welham S.J., Wade A., and Woolf A.S. Protein restriction in pregnancy is associated with increased apoptosis of mesenchymal cells at the start of rat metanephrogenesis. Kidney International 61 (2002) 1231-1242
37. Welham S.J., Riley P.R., Wade A., Hubank M., and Woolf A.S. Maternal diet programs embryonic kidney gene expression. Physiology Genomics 22 (2005) 48-56