Children's toxicology from bench to bed - Liver Injury (1): Drug-induced metabolic disturbance - Toxicity of 5-FU for pyrimidine metabolic disorders and pivalic acid for carnitine metabolism

Journal of Toxicological Sciences

Volumn 34, Issue 2 SPEC. ISS., 2009, Pages

  Ito, Tetsuya ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Carnitine; Dihydropyrimidinase; Dihydropyrimidine dehydrogenase; Pivalic acid

Indexed keywords

ACETYL COENZYME A; ANTIBIOTIC AGENT; CARNITINE; CEPHEM; DIHYDROPYRIMIDINASE; DIHYDROPYRIMIDINE DEHYDROGENASE; DRUG METABOLITE; FLUOROURACIL; KETONE BODY; LONG CHAIN FATTY ACID; PIVALIC ACID; PRODRUG; PYRIMIDINE; URACIL;

AUTISM; CHEMICAL STRUCTURE; CHILD HEALTH; CONFERENCE PAPER; CONVULSION; DIGESTIVE SYSTEM CANCER; DRUG ABSORPTION; DRUG DEGRADATION; DRUG EXCRETION; DRUG FORMULATION; DRUG INFORMATION; DRUG METABOLISM; DRUG PROTEIN BINDING; ENERGY YIELD; ENZYME DEFICIENCY; FATTY ACID OXIDATION; GLUCOSE BLOOD LEVEL; GROWTH RETARDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYPOCARNITINEMIA; HYPOGLYCEMIA; LIVER INJURY; LONG TERM CARE; METABOLIC DISORDER; MITOCHONDRION; NEUROBLASTOMA; NEWBORN SCREENING; OTITIS MEDIA; PROTEIN METABOLISM; PSYCHOMOTOR RETARDATION; UPPER RESPIRATORY TRACT INFECTION; URINARY EXCRETION;

EID: 67651171546     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.34.SP217     Document Type: Conference Paper

References (7)

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