Ethanol selectively impairs clathrin-mediated internalization in polarized hepatic cells

Biochemical Pharmacology

Volumn 78, Issue 6, 2009, Pages 648-655

  Fernandez, David J ^a   McVicker, Benita L ^b   Tuma, Dean J ^b   Tuma, Pamela L ^a  

^a CATHOLIC UNIVERSITY OF AMERICA   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Clathrin; Dynamin 2; Endocytosis; Ethanol; Liver injury; WIF B cells

Indexed keywords

ALCOHOL; CLATHRIN HEAVY CHAIN; DYNAMIN II;

ARTICLE; CAVEOLA; CELL MEMBRANE; CONTROLLED STUDY; ENDOCYTOSIS; GENE OVEREXPRESSION; HEAVY CHAIN; INTERNALIZATION; LIVER CELL; POLARIZATION; PRIORITY JOURNAL; SIGNAL DETECTION; SIGNAL TRANSDUCTION;

CAVEOLAE; CELL LINE; CELL POLARITY; CELLS, CULTURED; CLATHRIN; CLATHRIN HEAVY CHAINS; DRUG INTERACTIONS; ENDOCYTOSIS; ETHANOL; HEPATOCYTES; HUMANS; LIVER; MEMBRANE MICRODOMAINS; PROTEIN TRANSPORT; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR;

EID: 67651163421     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.05.012     Document Type: Article

References (29)

1. Tuma D.J., Casey C.A., and Sorrell M.F. Effects of ethanol on hepatic protein trafficking: impairment of receptor-mediated endocytosis. Alcohol Alcohol 25 (1990) 117-125
2. Tuma D.J., Casey C.A., and Sorrell M.F. Effects of alcohol on hepatic protein metabolism and trafficking. Alcohol Alcohol Suppl 1 (1991) 297-303
3. Tuma D.J., and Sorrell M.F. Effects of ethanol on protein trafficking in the liver. Semin Liver Dis 8 (1988) 69-80
4. McVicker B.L., and Casey C.A. Effects of ethanol on receptor-mediated endocytosis in the liver. Alcohol 19 (1999) 255-260
5. Joseph R.A., Shepard B.D., Kannarkat G.T., Rutledge T.M., Tuma D.J., and Tuma P.L. Microtubule acetylation and stability may explain alcohol-induced alterations in hepatic protein trafficking. Hepatology 47 (2008) 1745-1753
6. Clemens D.L., Casey C.A., Sorrell M.F., and Tuma D.J. Ethanol oxidation mediates impaired hepatic receptor-mediated enocytosis. Alcohol Clin Exp Res 22 (1998) 778-779
7. Shanks M.R., Cassio D., Lecoq O., and Hubbard A.L. An improved polarized rat hepatoma hybrid cell line. Generation and comparison with its hepatoma relatives and hepatocytes in vivo. J Cell Sci 107 Pt 4 (1994) 813-825
8. Griffo G., Hamon-Benais C., Angrand P.O., Fox M., West L., Lecoq O., et al. HNF4 and HNF1 as well as a panel of hepatic functions are extinguished and reexpressed in parallel in chromosomally reduced rat hepatoma-human fibroblast hybrids. J Cell Biol 121 (1993) 887-898
9. Ihrke G., Neufeld E.B., Meads T., Shanks M.R., Cassio D., Laurent M., et al. WIF-B cells: an in vitro model for studies of hepatocyte polarity. J Cell Biol 123 (1993) 1761-1775
10. Schaffert C.S., Todero S.L., McVicker B.L., Tuma P.L., Sorrell M.F., and Tuma D.J. WIF-B cells as a model for alcohol-induced hepatocyte injury. Biochem Pharmacol 67 (2004) 2167-2174
11. Conner S.D., and Schmid S.L. Regulated portals of entry into the cell. Nature 422 (2003) 37-44
12. Tuma D.J., Casey C.A., and Sorrell M.F. Chronic ethanol-induced impairments in receptor-mediated endocytosis of insulin in rat hepatocytes. Alcohol Clin Exp Res 15 (1991) 808-813
13. Dalke D.D., Sorrell M.F., Casey C.A., and Tuma D.J. Chronic ethanol administration impairs receptor-mediated endocytosis of epidermal growth factor by rat hepatocytes. Hepatology 12 (1990) 1085-1091
14. Bastaki M., Braiterman L.T., Johns D.C., Chen Y.H., and Hubbard A.L. Absence of direct delivery for single transmembrane apical proteins or their "Secretory" forms in polarized hepatic cells. Mol Biol Cell 13 (2002) 225-237
15. Nyasae L.K., Hubbard A.L., and Tuma P.L. Transcytotic efflux from early endosomes is dependent on cholesterol and glycosphingolipids in polarized hepatic cells. Mol Biol Cell 14 (2003) 2689-2705
16. Ramnarayanan S.P., Cheng C.A., Bastaki M., and Tuma P.L. Exogenous MAL reroutes selected hepatic apical proteins into the direct pathway in WIF-B cells. Mol Biol Cell 18 (2007) 2707-2715
17. Geny B., and Popoff M.R. Bacterial protein toxins and lipids: pore formation or toxin entry into cells. Biol Cell 98 (2006) 667-678
18. Casey C.A., Camacho K.B., and Tuma D.J. The effects of chronic ethanol administration on the rates of internalization of various ligands during hepatic endocytosis. Biochim Biophys Acta 1134 (1992) 96-104
19. Tuma P.L., and Hubbard A.L. Transcytosis: crossing cellular barriers. Physiol Rev 83 (2003) 871-932
20. Liu Y.W., Surka M.C., Schroeter T., Lukiyanchuk V., and Schmid S.L. Isoform and splice-variant specific functions of dynamin-2 revealed by analysis of conditional knock-out cells. Mol Biol Cell 19 (2008) 5347-5359
21. Hoek J.B., and Pastorino J.G. Ethanol, oxidative stress, and cytokine-induced liver cell injury. Alcohol 27 (2002) 63-68
22. Hoek J.B., and Pastorino J.G. Cellular signaling mechanisms in alcohol-induced liver damage. Semin Liver Dis 24 (2004) 257-272
23. Potter B.J., Chapman R.W., Nunes R.M., Sorrentino D., and Sherlock S. Transferrin metabolism in alcoholic liver disease. Hepatology 5 (1985) 714-721
24. van de Wiel A., Delacroix D.L., van Hattum J., Schuurman H.J., and Kater L. Characteristics of serum IgA and liver IgA deposits in alcoholic liver disease. Hepatology 7 (1987) 95-99
25. Volentine G.D., Ogden K.A., Kortje D.K., Tuma D.J., and Sorrell M.F. Role of acetaldehyde in the ethanol-induced impairment of hepatic glycoprotein secretion in the rat in vivo. Hepatology 7 (1987) 490-495
26. Volentine G.D., Tuma D.J., and Sorrell M.F. Subcellular location of secretory proteins retained in the liver during the ethanol-induced inhibition of hepatic protein secretion in the rat. Gastroenterology 90 (1986) 158-165
27. Volentine G.D., Tuma D.J., and Sorrell M.F. Acute effects of ethanol on hepatic glycoprotein secretion in the rat in vivo. Gastroenterology 86 (1984) 225-229
28. Rodriguez-Boulan E., and Musch A. Protein sorting in the Golgi complex: shifting paradigms. Biochim Biophys Acta 1744 (2005) 455-464
29. Saucan L., and Palade G.E. Differential colchicine effects on the transport of membrane and secretory proteins in rat hepatocytes in vivo: bipolar secretion of albumin. Hepatology 15 (1992) 714-721