Valproate-induced reversible pseudoatrophy of the brain and hyperammonemic encephalopathy in a bipolar patient

Australian and New Zealand Journal of Psychiatry

Volumn 43, Issue 5, 2009, Pages 484-485

  Abreu, Lena Nabuco ^a   Issler, Cilly ^a   Lafer, Beny ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

VALPROIC ACID;

ADULT; AMMONIA BLOOD LEVEL; AMNESIA; APATHY; ARTICLE; BIPOLAR DISORDER; BRAIN ATROPHY; CASE REPORT; CATATONIA; COMPUTER ASSISTED TOMOGRAPHY; CONFUSION; DISORIENTATION; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; DRUG WITHDRAWAL; ELECTROCONVULSIVE THERAPY; FEMALE; HUMAN; HYPERAMMONEMIA; LETHARGY; MENTAL PATIENT; PARKINSONISM; SIDE EFFECT; SPEECH DISORDER; ATROPHY; BRAIN; CHEMICALLY INDUCED DISORDER; LETTER; MIDDLE AGED; PATHOLOGY; TOXICITY AND INTOXICATION;

ATROPHY; BIPOLAR DISORDER; BRAIN; FEMALE; HUMANS; HYPERAMMONEMIA; MIDDLE AGED; NEUROTOXICITY SYNDROMES; VALPROIC ACID;

EID: 67651156198     PISSN: 00048674     EISSN: 14401614     Source Type: Journal    
DOI: 10.1080/00048670902821606     Document Type: Article

References (4)

1. Guerrine R, Belmonte A, Canapicchi R, Casalini C, Perucca E. Reversible pseudoatrophy of the brain and mental deterioration associated with valproate treatment. Epilepsia 1998; 39:27-32.
2. Armon C, Shin C, Miller P et al. Reversible parkinsonism and cognitive impairment with chronic valproate use. Neurology 1996; 47:626-635.
3. Segura-Bruna N, Rodriguez-Campello A, Puente V, Roquer J. Valproate-induced hyperammonemic encephalopathy. Acta Neurol Scand 2006; 114:1-7.
4. Carr RB, Shrewsburry K. Hyperammonemia due to valproic acid in the psychiatry setting. Am J Psychiatry 2007; 164: 1020-1027.